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Results: 1-25 | 26-26
Results: 1-25/26
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia
Authors: Moroni, F Meli, E Peruginelli, F Chiarugi, A Cozzi, A Picca, R Romagnoli, P Pellicciari, R Pellegrini-Giampietro, DE
Citation: F. Moroni et al., Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia, CELL DEAT D, 8(9), 2001, pp. 921-932
Homology model of the closed, functionally active, form of the amino terminal domain of mGluR1
Authors: Costantino, C Macchiarulo, A Pellicciari, R
Citation: C. Costantino et al., Homology model of the closed, functionally active, form of the amino terminal domain of mGluR1, BIO MED CH, 9(4), 2001, pp. 847-852
Synthesis and biological evaluation of 2-(3 '-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist
Authors: Costantino, G Maltoni, K Marinozzi, M Camaioni, E Prezeau, L Pin, JP Pellicciari, R
Citation: G. Costantino et al., Synthesis and biological evaluation of 2-(3 '-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist, BIO MED CH, 9(2), 2001, pp. 221-227
Design, synthesis and preliminary evaluation of novel 3 '-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors
Authors: Pellicciari, R Costantino, G Marinozzi, M Macchiarulo, A Amori, L Flor, PJ Gasparini, F Kuhn, R Urwyler, S
Citation: R. Pellicciari et al., Design, synthesis and preliminary evaluation of novel 3 '-substituted carboxycyclopropylglycines as antagonists at group 2 metabotropic glutamate receptors, BIOORG MED, 11(24), 2001, pp. 3179-3182
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis
Authors: Costantino, G Macchiarulo, A Camaioni, E Pellicciari, R
Citation: G. Costantino et al., Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis, J MED CHEM, 44(23), 2001, pp. 3786-3794
QSAR and molecular modeling studies of baclofen analogues as GABA(B) agonists. Insights into the role of the aromatic moiety in GABA(B) binding and activation
Authors: Costantino, G Macchiarulo, A Guadix, AE Pellicciari, R
Citation: G. Costantino et al., QSAR and molecular modeling studies of baclofen analogues as GABA(B) agonists. Insights into the role of the aromatic moiety in GABA(B) binding and activation, J MED CHEM, 44(11), 2001, pp. 1827-1832
Use of RP-HPLC on a dynamically coated artificial membrane to predict intestinal absorption of bile acids
Authors: Natalini, B Camaioni, E Colagioia, S Pellicciari, R
Citation: B. Natalini et al., Use of RP-HPLC on a dynamically coated artificial membrane to predict intestinal absorption of bile acids, CHROMATOGR, 53, 2001, pp. S453-S455
Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III
Authors: Amori, L Costantino, G Marinozzi, M Pellicciari, R Gasparini, F Flor, PJ Kuhn, R Vranesic, I
Citation: L. Amori et al., Synthesis, molecular modeling and preliminary biological evaluation of 1-amino-3-phosphono-3-cyclopentene-1-carboxylic acid and 1-amino-3-phosphono-2-cyclopentene-1-carboxylic acid, two novel agonists of metabotropic glutamate receptors of group III, BIOORG MED, 10(13), 2000, pp. 1447-1450
Synthesis of methano[60]fullerenephosphonic- and methano[60]fullerene-diphosphonic acids
Authors: Pellicciari, R Natalini, B Amori, L Marinozzi, M Seraglia, R
Citation: R. Pellicciari et al., Synthesis of methano[60]fullerenephosphonic- and methano[60]fullerene-diphosphonic acids, SYNLETT, (12), 2000, pp. 1816-1818
Novel enantioselective synthesis of (2S,2 ' R,3 ' R)-2-(2 ',3 '-dicarboxycyclopropyl)glycine (DCG-IV)
Authors: Marinozzi, M Pellicciari, R
Citation: M. Marinozzi et R. Pellicciari, Novel enantioselective synthesis of (2S,2 ' R,3 ' R)-2-(2 ',3 '-dicarboxycyclopropyl)glycine (DCG-IV), TETRAHEDR L, 41(47), 2000, pp. 9125-9128
Evaluation of hydrophobic/hydrophilic balance of bile acids by comparativemolecular field analysis (CoMFA)
Authors: Costantino, G Wolf, C Natalini, B Pellicciari, R
Citation: G. Costantino et al., Evaluation of hydrophobic/hydrophilic balance of bile acids by comparativemolecular field analysis (CoMFA), STEROIDS, 65(9), 2000, pp. 483-489
Conservation of the ligand recognition site of metabotropic glutamate receptors during evolution
Authors: Parmentier, ML Galvez, T Acher, F Peyre, B Pellicciari, R Grau, Y Bockaert, J Pin, JP
Citation: Ml. Parmentier et al., Conservation of the ligand recognition site of metabotropic glutamate receptors during evolution, NEUROPHARM, 39(7), 2000, pp. 1119-1131
C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis
Authors: Bisaglia, M Natalini, B Pellicciari, R Straface, E Malorni, W Monti, D Franceschi, C Schettini, G
Citation: M. Bisaglia et al., C-3-fullero-tris-methanodicarboxylic acid protects cerebellar granule cells from apoptosis, J NEUROCHEM, 74(3), 2000, pp. 1197-1204
Carboxyfullerenes protect human keratinocytes from ultraviolet-B-induced apoptosis
Authors: Fumelli, C Marconi, A Salvioli, S Straface, E Malorni, W Offidani, AM Pellicciari, R Schettini, G Giannetti, A Monti, D Franceschi, C Pincelli, C
Citation: C. Fumelli et al., Carboxyfullerenes protect human keratinocytes from ultraviolet-B-induced apoptosis, J INVES DER, 115(5), 2000, pp. 835-841
C60 carboxyfullerene exerts a protective activity against oxidative stress-induced apoptosis in human peripheral blood mononuclear cells
Authors: Monti, D Moretti, L Salvioli, S Straface, E Malorni, W Pellicciari, R Schettini, G Bisaglia, M Pincelli, C Fumelli, C Bonafe, M Franceschi, C
Citation: D. Monti et al., C60 carboxyfullerene exerts a protective activity against oxidative stress-induced apoptosis in human peripheral blood mononuclear cells, BIOC BIOP R, 277(3), 2000, pp. 711-717
Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C-60 derivatives
Authors: Natalini, B Capodiferro, V Mattoli, L Marinozzi, M Costantino, G Pellicciari, R
Citation: B. Natalini et al., Chromatographic separation and evaluation of the lipophilicity by reversed-phase high-performance liquid chromatography of fullerene-C-60 derivatives, J CHROMAT A, 847(1-2), 1999, pp. 339-343
Metabotropic G-protein-coupled glutamate receptors as therapeutic targets
Authors: Pellicciari, R Costantino, G
Citation: R. Pellicciari et G. Costantino, Metabotropic G-protein-coupled glutamate receptors as therapeutic targets, CURR OP C B, 3(4), 1999, pp. 433-440
1-aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3 '-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia
Authors: Pellegrini-Giampietro, DE Cozzi, A Peruginelli, F Leonardi, P Meli, E Pellicciari, R Moroni, F
Citation: De. Pellegrini-giampietro et al., 1-aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3 '-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia, EUR J NEURO, 11(10), 1999, pp. 3637-3647
Biochemical and electrophysiological studies on (S)-(+)-2-(3 '-carboxybicyclo[1.1.1]pentyl)-glycine (CBPG), a novel mGlu(5) receptor agonist endowed with mGlu(1) receptor antagonist activity
Authors: Mannaioni, G Attucci, S Missanelli, A Pellicciari, R Corradetti, R Moroni, F
Citation: G. Mannaioni et al., Biochemical and electrophysiological studies on (S)-(+)-2-(3 '-carboxybicyclo[1.1.1]pentyl)-glycine (CBPG), a novel mGlu(5) receptor agonist endowed with mGlu(1) receptor antagonist activity, NEUROPHARM, 38(7), 1999, pp. 917-926
Protection with metabotropic glutamate 1 receptor antagonists in models ofischemic neuronal death: time-course and mechanisms
Authors: Pellegrini-Giampietro, DE Peruginelli, F Meli, E Cozzi, A Albani-Torregrossa, S Pellicciari, R Moroni, F
Citation: De. Pellegrini-giampietro et al., Protection with metabotropic glutamate 1 receptor antagonists in models ofischemic neuronal death: time-course and mechanisms, NEUROPHARM, 38(10), 1999, pp. 1607-1619
Antagonist pharmacology of metabotropic glutamate receptors coupled to phospholipase D activation in adult rat hippocampus: Focus on (2R,1 ' S,2 ' R,3 ' S)-2-(2 '-carboxy-3 '-phenylcyclopropyl)glycine versus 3,5-dihydroxyphenylglycine
Authors: Albani-Torregrossa, S Attucci, S Marinozzi, M Pellicciari, R Moroni, F Pellegrini-Giampietro, DE
Citation: S. Albani-torregrossa et al., Antagonist pharmacology of metabotropic glutamate receptors coupled to phospholipase D activation in adult rat hippocampus: Focus on (2R,1 ' S,2 ' R,3 ' S)-2-(2 '-carboxy-3 '-phenylcyclopropyl)glycine versus 3,5-dihydroxyphenylglycine, MOLEC PHARM, 55(4), 1999, pp. 699-707
Modeling of amino-terminal domains of group I metabotropic glutamate receptors: Structural motifs affecting ligand selectivity
Authors: Costantino, G Macchiarulo, A Pellicciari, R
Citation: G. Costantino et al., Modeling of amino-terminal domains of group I metabotropic glutamate receptors: Structural motifs affecting ligand selectivity, J MED CHEM, 42(26), 1999, pp. 5390-5401
Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parametersaffecting potency and selectivity
Authors: Costantino, G Macchiarulo, A Pellicciari, R
Citation: G. Costantino et al., Pharmacophore models of group I and group II metabotropic glutamate receptor agonists. Analysis of conformational, steric, and topological parametersaffecting potency and selectivity, J MED CHEM, 42(15), 1999, pp. 2816-2827
(2R,1 ' S,2 ' R,3 ' S)-2-(2 '-carboxy-3 '-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipaseD-coupled metabotropic glutamate receptors: Asymmetric synthesis and preliminary biological properties
Authors: Pellicciari, R Marinozzi, M Costantino, G Natalini, B Moroni, F Pellegrini-Giampietro, D
Citation: R. Pellicciari et al., (2R,1 ' S,2 ' R,3 ' S)-2-(2 '-carboxy-3 '-phenylcyclopropyl)glycine (PCCG-13), the first potent and selective competitive antagonist of phospholipaseD-coupled metabotropic glutamate receptors: Asymmetric synthesis and preliminary biological properties, J MED CHEM, 42(14), 1999, pp. 2716-2720
A new synthesis of carboxyterfenadine (fexofenadine) and its bioisosteric tetrazole analogs
Authors: Di Giacomo, B Coletta, D Natalini, B Ni, MH Pellicciari, R
Citation: B. Di Giacomo et al., A new synthesis of carboxyterfenadine (fexofenadine) and its bioisosteric tetrazole analogs, FARMACO, 54(9), 1999, pp. 600-610
Risultati: 1-25 | 26-26