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Results: 1-19 |
Results: 19
Identification of differentially expressed genes in experimental models ofthe tumor microenvironment using differential display
Authors: Knowles, HJ Phillips, RM
Citation: Hj. Knowles et Rm. Phillips, Identification of differentially expressed genes in experimental models ofthe tumor microenvironment using differential display, ANTICANC R, 21(4A), 2001, pp. 2305-2311
Influence of extracellular pH on the cytotoxicity and DNA damage of a series of indolequinone compounds
Authors: Phillips, RM Ward, TH
Citation: Rm. Phillips et Th. Ward, Influence of extracellular pH on the cytotoxicity and DNA damage of a series of indolequinone compounds, ANTICANC R, 21(3B), 2001, pp. 1795-1801
Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions
Authors: Wolska, BM Vijayan, K Arteaga, GM Konhilas, JP Phillips, RM Kim, R Naya, T Leiden, JM Martin, AF de Tombe, PP Solaro, RJ
Citation: Bm. Wolska et al., Expression of slow skeletal troponin I in adult transgenic mouse heart muscle reduces the force decline observed during acidic conditions, J PHYSL LON, 536(3), 2001, pp. 863-870
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents
Authors: Wright, CW Addae-Kyereme, J Breen, AG Brown, JE Cox, MF Croft, SL Gokcek, Y Kendrick, H Phillips, RM Pollet, PL
Citation: Cw. Wright et al., Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents, J MED CHEM, 44(19), 2001, pp. 3187-3194
A novel strategy for NQO1 (NAD(P)H : quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9
Authors: Choudry, GA Stewart, PAH Double, JA Krul, MRL Naylor, B Flannigan, GM Shah, TK Brown, JE Phillips, RM
Citation: Ga. Choudry et al., A novel strategy for NQO1 (NAD(P)H : quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9, BR J CANC, 85(8), 2001, pp. 1137-1146
Genotyping of NAD(P)H : quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo
Authors: Phillips, RM Burger, AM Fiebig, HH Double, JA
Citation: Rm. Phillips et al., Genotyping of NAD(P)H : quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo, BIOCH PHARM, 62(10), 2001, pp. 1371-1377
Hollow fiber assay for tumor angiogenesis
Authors: Phillips, RM Bibby, MC
Citation: Rm. Phillips et Mc. Bibby, Hollow fiber assay for tumor angiogenesis, METH MOL M, 46, 2001, pp. 87-93
Molecular modelling of human DT-Diaphorase for enzyme-directed bioreductive drug design
Authors: Doughty, SW Phillips, RM
Citation: Sw. Doughty et Rm. Phillips, Molecular modelling of human DT-Diaphorase for enzyme-directed bioreductive drug design, MOL SIMULAT, 24(4-6), 2000, pp. 209
Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy
Authors: Evans, CC Pena, JR Phillips, RM Muthuchamy, M Wieczorek, DF Solaro, RJ Wolska, BM
Citation: Cc. Evans et al., Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy, AM J P-HEAR, 279(5), 2000, pp. H2414-H2423
Computer palms
Authors: Lewis, AT Hsu, S Phillips, RM Lee, JA
Citation: At. Lewis et al., Computer palms, J AM ACAD D, 42(6), 2000, pp. 1073-1075
Flow past a cylinder using a semi-Lagrangian spectral element method
Authors: Phillips, RM Phillips, TN
Citation: Rm. Phillips et Tn. Phillips, Flow past a cylinder using a semi-Lagrangian spectral element method, APPL NUM M, 33(1-4), 2000, pp. 251-257
Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: Implications for enzyme-directed bioreductive drug development
Authors: Phillips, RM Burger, AM Loadman, PM Jarrett, CM Swaine, DJ Fiebig, HH
Citation: Rm. Phillips et al., Predicting tumor responses to mitomycin C on the basis of DT-diaphorase activity or drug metabolism by tumor homogenates: Implications for enzyme-directed bioreductive drug development, CANCER RES, 60(22), 2000, pp. 6384-6390
The relative importance of NADPH: Cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positions
Authors: Saunders, MP Jaffar, M Patterson, AV Nolan, J Naylor, MA Phillips, RM Harris, AL Stratford, IJ
Citation: Mp. Saunders et al., The relative importance of NADPH: Cytochrome c (P450) reductase for determining the sensitivity of human tumour cells to the indolequinone EO9 and related analogues lacking functionality at the C-2 and C-3 positions, BIOCH PHARM, 59(8), 2000, pp. 993-996
Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice
Authors: Loadman, PM Phillips, RM Lim, LE Bibby, MC
Citation: Pm. Loadman et al., Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice, BIOCH PHARM, 59(7), 2000, pp. 831-837
Bioreductive activation of a series of indolequinones by human DT-diaphorase: Structure-activity relationships
Authors: Phillips, RM Naylor, MA Jaffar, M Doughty, SW Everett, SA Breen, AG Choudry, GA Stratford, IJ
Citation: Rm. Phillips et al., Bioreductive activation of a series of indolequinones by human DT-diaphorase: Structure-activity relationships, J MED CHEM, 42(20), 1999, pp. 4071-4080
High-power klystrons for the Next Linear Collider
Authors: Phillips, RM Sprehn, DW
Citation: Rm. Phillips et Dw. Sprehn, High-power klystrons for the Next Linear Collider, P IEEE, 87(5), 1999, pp. 738-751
Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin
Authors: Wolska, BM Keller, RS Evans, CC Palmiter, KA Phillips, RM Muthuchamy, M Oehlenschlager, J Wieczorek, DF de Tombe, PP Solaro, RJ
Citation: Bm. Wolska et al., Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin, CIRCUL RES, 84(7), 1999, pp. 745-751
Inhibition of DT-diaphorase (NAD(P)H : quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid(FAA): Implications for bioreductive drug development
Authors: Phillips, RM
Citation: Rm. Phillips, Inhibition of DT-diaphorase (NAD(P)H : quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid(FAA): Implications for bioreductive drug development, BIOCH PHARM, 58(2), 1999, pp. 303-310
Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells: Implications for anticancer drug screening programs
Authors: Phillips, RM Pearce, J Loadman, PM Bibby, MC Cooper, PA Swaine, DJ Double, JA
Citation: Rm. Phillips et al., Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells: Implications for anticancer drug screening programs, CANCER RES, 58(23), 1998, pp. 5263-5266
Risultati: 1-19 |