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Results: 1-14 |
Results: 14
Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors
Authors: Janusz, MJ Hookfin, EB Heitmeyer, SA Woessner, JF Freemont, AJ Hoyland, JA Brown, KK Hsieh, LC Almstead, NG De, B Natchus, MG Pikul, S Taiwo, YO
Citation: Mj. Janusz et al., Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors, OSTEO CART, 9(8), 2001, pp. 751-760
Heterocycle-based MMP inhibitors with P2 ' substituents
Authors: Pikul, S Dunham, KM Almstead, NG De, B Natchus, MG Taiwo, YO Williams, LE Hynd, BA Hsieh, LC Janusz, MJ Gu, F Mieling, GE
Citation: S. Pikul et al., Heterocycle-based MMP inhibitors with P2 ' substituents, BIOORG MED, 11(8), 2001, pp. 1009-1013
The development of new carboxylic acid-based MMP inhibitors derived from acyclohexylglycine scaffold
Authors: Tullis, JS Laufersweiler, MJ VanRens, JC Natchus, MG Bookland, RG Almstead, NG Pikul, S De, B Hsieh, LC Janusz, MJ Branch, TM Peng, SX Jin, YY Hudlicky, T Oppong, K
Citation: Js. Tullis et al., The development of new carboxylic acid-based MMP inhibitors derived from acyclohexylglycine scaffold, BIOORG MED, 11(15), 2001, pp. 1975-1979
Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines
Authors: Natchus, MG Bookland, RG Laufersweiler, MJ Pikul, S Almstead, NG De, B Janusz, MJ Hsieh, LC Gu, F Pokross, ME Patel, VS Garver, SM Peng, SX Branch, TM King, SL Baker, TR Foltz, DJ Mieling, GE
Citation: Mg. Natchus et al., Development of new carboxylic acid-based MMP inhibitors derived from functionalized propargylglycines, J MED CHEM, 44(7), 2001, pp. 1060-1071
Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases
Authors: Pikul, S Ohler, NE Ciszewski, G Laufersweiler, MC Almstead, NG De, B Natchus, MG Hsieh, LC Janusz, MJ Peng, SX Branch, TM King, SL Taiwo, YO Mieling, GE
Citation: S. Pikul et al., Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases, J MED CHEM, 44(16), 2001, pp. 2499-2502
Design and synthesis of piperazine-based matrix metalloproteinase inhibitors
Authors: Cheng, MY De, B Pikul, S Almstead, NG Natchus, MG Anastasio, MV McPhail, SJ Snider, CE Taiwo, YO Chen, LY Dunaway, CM Gu, F Dowty, ME Mieling, GE Janusz, MJ Wang-Weigand, S
Citation: My. Cheng et al., Design and synthesis of piperazine-based matrix metalloproteinase inhibitors, J MED CHEM, 43(3), 2000, pp. 369-380
Development of new hydroxamate matrix metalloproteinase inhibitors derivedfrom functionalized 4-aminoprolines
Authors: Natchus, MG Bookland, RG De, B Almstead, NG Pikul, S Janusz, MJ Heitmeyer, SA Hookfin, EB Hsieh, LC Dowty, ME Dietsch, CR Patel, VS Garver, SM Gu, F Pokross, ME Mieling, GE Baker, TR Foltz, DJ Peng, SX Bornes, DM Strojnowski, MJ Taiwo, YO
Citation: Mg. Natchus et al., Development of new hydroxamate matrix metalloproteinase inhibitors derivedfrom functionalized 4-aminoprolines, J MED CHEM, 43(26), 2000, pp. 4948-4963
Gas chromatographic mass spectrometric analysis of hydroxylamine for monitoring the metabolic hydrolysis of metalloprotease inhibitors in rat and human liver microsomes
Authors: Peng, SX Strojnowski, MJ Hu, JK Smith, BJ Eichhold, TH Wehmeyer, KR Pikul, S Almstead, NG
Citation: Sx. Peng et al., Gas chromatographic mass spectrometric analysis of hydroxylamine for monitoring the metabolic hydrolysis of metalloprotease inhibitors in rat and human liver microsomes, J CHROMAT B, 724(1), 1999, pp. 181-187
Application of LC-NMR and LC-MS to the identification of degradation products of a protease inhibitor in dosage formulations
Authors: Peng, SX Borah, B Dobson, RLM Liu, YD Pikul, S
Citation: Sx. Peng et al., Application of LC-NMR and LC-MS to the identification of degradation products of a protease inhibitor in dosage formulations, J PHARM B, 20(1-2), 1999, pp. 75-89
Oxazolidinone to succinamide: a novel rearrangement reaction
Authors: Cheng, MY De, B Wahl, CT Almstead, NG Natchus, MG Pikul, S
Citation: My. Cheng et al., Oxazolidinone to succinamide: a novel rearrangement reaction, TETRAHEDR L, 40(33), 1999, pp. 5975-5977
Crystal structure of the stromelysin catalytic domain at 2.0 angstrom resolution: Inhibitor-induced conformational changes
Authors: Chen, LY Rydel, TJ Gu, F Dunaway, CM Pikul, S Dunham, KM Barnett, BL
Citation: Ly. Chen et al., Crystal structure of the stromelysin catalytic domain at 2.0 angstrom resolution: Inhibitor-induced conformational changes, J MOL BIOL, 293(3), 1999, pp. 545-557
Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold
Authors: Cheng, MY De, B Almstead, NG Pikul, S Dowty, ME Dietsch, CR Dunaway, CM Gu, F Hsieh, LC Janusz, MJ Taiwo, YO Natchus, MG Hudlicky, T Mandel, M
Citation: My. Cheng et al., Design, synthesis, and biological evaluation of matrix metalloproteinase inhibitors derived from a modified proline scaffold, J MED CHEM, 42(26), 1999, pp. 5426-5436
Design, synthesis, and biological evaluation of potent thiazine- and thiazepine-based matrix metalloproteinase inhibitors
Authors: Almstead, NG Bradley, RS Pikul, S De, B Natchus, MG Taiwo, YO Gu, F Williams, LE Hynd, BA Janusz, MJ Dunaway, CM Mieling, GE
Citation: Ng. Almstead et al., Design, synthesis, and biological evaluation of potent thiazine- and thiazepine-based matrix metalloproteinase inhibitors, J MED CHEM, 42(22), 1999, pp. 4547-4562
Design and synthesis of phosphinamide-based hydroxamic acids as inhibitorsof matrix metalloproteinases
Authors: Pikul, S Dunham, KLM Almstead, NG De, B Natchus, MG Anastasio, MV McPhail, SJ Snider, CE Taiwo, YO Chen, LY Dunaway, CM Gu, F Mieling, GE
Citation: S. Pikul et al., Design and synthesis of phosphinamide-based hydroxamic acids as inhibitorsof matrix metalloproteinases, J MED CHEM, 42(1), 1999, pp. 87-94
Risultati: 1-14 |