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Results: 1-25 | 26-34
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SCHIZOPHRENIA AND L-745,870, A NOVEL DOPAMINE D4 RECEPTOR ANTAGONIST
Authors: BRISTOW LJ KRAMER MS KULAGOWSKI J PATEL S RAGAN CI SEABROOK GR
Citation: Lj. Bristow et al., SCHIZOPHRENIA AND L-745,870, A NOVEL DOPAMINE D4 RECEPTOR ANTAGONIST, Trends in pharmacological sciences, 18(6), 1997, pp. 186-188
L-745,870, A SUBTYPE-SELECTIVE DOPAMINE-D4 RECEPTOR ANTAGONIST, DOES NOT EXHIBIT A NEUROLEPTIC-LIKE PROFILE IN RODENT BEHAVIORAL-TESTS
Authors: BRISTOW LJ COLLINSON N COOK GP CURTIS N FREEDMAN SB KULAGOWSKI JJ LEESON PD PATEL S RAGAN CI RIDGILL M SAYWELL KL TRICKLEBANK MD
Citation: Lj. Bristow et al., L-745,870, A SUBTYPE-SELECTIVE DOPAMINE-D4 RECEPTOR ANTAGONIST, DOES NOT EXHIBIT A NEUROLEPTIC-LIKE PROFILE IN RODENT BEHAVIORAL-TESTS, The Journal of pharmacology and experimental therapeutics, 283(3), 1997, pp. 1256-1263
BIOLOGICAL PROFILE OF L-745,870, A SELECTIVE ANTAGONIST WITH HIGH-AFFINITY FOR THE DOPAMINE-D4 RECEPTOR
Authors: PATEL S FREEDMAN S CHAPMAN KL EMMS F FLETCHER AE KNOWLES M MARWOOD R MCALLISTER G MYERS J PATEL S CURTIS N KULAGOWSKI JJ LEESON PD RIDGILL M GRAHAM M MATHESON S RATHBONE D WATT AP BRISTOW LJ RUPNIAK NMJ BASKIN E LYNCH JJ RAGAN CI
Citation: S. Patel et al., BIOLOGICAL PROFILE OF L-745,870, A SELECTIVE ANTAGONIST WITH HIGH-AFFINITY FOR THE DOPAMINE-D4 RECEPTOR, The Journal of pharmacology and experimental therapeutics, 283(2), 1997, pp. 636-647
4-HETEROCYCLYLPIPERIDINES AS SELECTIVE HIGH-AFFINITY LIGANDS AT THE HUMAN DOPAMINE D4 RECEPTOR
Authors: ROWLEY M COLLINS I BROUGHTON HB DAVEY WB BAKER R EMMS F MARWOOD R PATEL S PATEL S RAGAN CI FREEDMAN SB BALL R LEESON PD
Citation: M. Rowley et al., 4-HETEROCYCLYLPIPERIDINES AS SELECTIVE HIGH-AFFINITY LIGANDS AT THE HUMAN DOPAMINE D4 RECEPTOR, Journal of medicinal chemistry, 40(15), 1997, pp. 2374-2385
[H-3] L-655,708, A NOVEL LIGAND SELECTIVE FOR THE BENZODIAZEPINE SITEOF GABA(A) RECEPTORS WHICH CONTAIN THE ALPHA-5 SUBUNIT
Authors: QUIRK K BLURTON P FLETCHER S LEESON P TANG F MELLILO D RAGAN CI MCKERNAN RM
Citation: K. Quirk et al., [H-3] L-655,708, A NOVEL LIGAND SELECTIVE FOR THE BENZODIAZEPINE SITEOF GABA(A) RECEPTORS WHICH CONTAIN THE ALPHA-5 SUBUNIT, Neuropharmacology, 35(9-10), 1996, pp. 1331-1335
GENERATION AND CHARACTERIZATION OF STABLE CELL-LINES EXPRESSING RECOMBINANT HUMAN N-METHYL-D-ASPARTATE RECEPTOR SUBTYPES
Authors: GRIMWOOD S LEBOURDELLES B ATACK JR BARTON C COCKETT W COOK SM GILBERT E HUTSON PH MCKERNAN RM MYERS J RAGAN CI WINGROVE PB WHITING PJ
Citation: S. Grimwood et al., GENERATION AND CHARACTERIZATION OF STABLE CELL-LINES EXPRESSING RECOMBINANT HUMAN N-METHYL-D-ASPARTATE RECEPTOR SUBTYPES, Journal of neurochemistry, 66(6), 1996, pp. 2239-2247
MODULATION OF CA-45(2+) INFLUX INTO CELLS STABLY EXPRESSING RECOMBINANT HUMAN NMDA RECEPTORS BY LIGANDS ACTING AT DISTINCT RECOGNITION SITES
Authors: GRIMWOOD S GILBERT E RAGAN CI HUTSON PH
Citation: S. Grimwood et al., MODULATION OF CA-45(2+) INFLUX INTO CELLS STABLY EXPRESSING RECOMBINANT HUMAN NMDA RECEPTORS BY LIGANDS ACTING AT DISTINCT RECOGNITION SITES, Journal of neurochemistry, 66(6), 1996, pp. 2589-2595
L)PIPERAZIN-1-YL]METHYL]-1H-PYRROLO[2,3-B]PYRIDINE - AN ANTAGONIST WITH HIGH-AFFINITY AND SELECTIVITY FOR THE HUMAN DOPAMINE D-4 RECEPTOR
Authors: KULAGOWSKI JJ BROUGHTON HB CURTIS NR MAWER IM RIDGILL MP BAKER R EMMS F FREEDMAN SB MARWOOD R PATEL S PATEL S RAGAN CI LEESON PD
Citation: Jj. Kulagowski et al., L)PIPERAZIN-1-YL]METHYL]-1H-PYRROLO[2,3-B]PYRIDINE - AN ANTAGONIST WITH HIGH-AFFINITY AND SELECTIVITY FOR THE HUMAN DOPAMINE D-4 RECEPTOR, Journal of medicinal chemistry, 39(10), 1996, pp. 1941-1942
ETHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE - A POTENT, SELECTIVE ANTAGONIST AT HUMAN CLONED DOPAMINE D4 RECEPTORS
Authors: ROWLEY M BROUGHTON HB COLLINS I BAKER R EMMS F MARWOOD R PATEL S PATEL S RAGAN CI FREEDMAN SB LEESON PD
Citation: M. Rowley et al., ETHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE - A POTENT, SELECTIVE ANTAGONIST AT HUMAN CLONED DOPAMINE D4 RECEPTORS, Journal of medicinal chemistry, 39(10), 1996, pp. 1943-1945
L-745,870 )PIPERAZIN-1-YL]METHYL)-1H-PYRROLO[2,3-B]PYRIDINE) - A HIGH-AFFINITY AND SELECTIVE DOPAMINE D4 RECEPTOR ANTAGONIST
Authors: PATEL S PATEL S MARWOOD R FLETCHER AE KULAGOWSKI J RAGAN CI LEESON PD FREEDMAN SB
Citation: S. Patel et al., L-745,870 )PIPERAZIN-1-YL]METHYL)-1H-PYRROLO[2,3-B]PYRIDINE) - A HIGH-AFFINITY AND SELECTIVE DOPAMINE D4 RECEPTOR ANTAGONIST, British Journal of Pharmacology, 119, 1996, pp. 30-30
LACK OF EFFECT OF THE DOPAMINE D-4 RECEPTOR ANTAGONIST, L-745,870 ON AMPHETAMINE-INDUCED BEHAVIORS IN RODENTS
Authors: BRISTOW LJ SAYWELL KL COOK GP KULAGOWSKI JJ LEESON PD RAGAN CI TRICKLEBANK MD
Citation: Lj. Bristow et al., LACK OF EFFECT OF THE DOPAMINE D-4 RECEPTOR ANTAGONIST, L-745,870 ON AMPHETAMINE-INDUCED BEHAVIORS IN RODENTS, British Journal of Pharmacology, 119, 1996, pp. 210-210
FUNCTIONAL RELEVANCE OF DOPAMINE-RECEPTORS
Authors: SEABROOK GR PATEL S HUTSON PH RAGAN CI BRISTOW LJ
Citation: Gr. Seabrook et al., FUNCTIONAL RELEVANCE OF DOPAMINE-RECEPTORS, Trends in pharmacological sciences, 16(12), 1995, pp. 406-407
THE PHARMACOLOGY OF THE BENZODIAZEPINE SITE OF THE GABA-A RECEPTOR ISDEPENDENT ON THE TYPE OF GAMMA-SUBUNIT PRESENT
Authors: MCKERNAN RM WAFFORD K QUIRK K HADINGHAM KL HARLEY EA RAGAN CI WHITING PJ
Citation: Rm. Mckernan et al., THE PHARMACOLOGY OF THE BENZODIAZEPINE SITE OF THE GABA-A RECEPTOR ISDEPENDENT ON THE TYPE OF GAMMA-SUBUNIT PRESENT, Journal of receptor and signal transduction research, 15(1-4), 1995, pp. 173-183
SULFATED COMPOUNDS ATTENUATE BETA-AMYLOID TOXICITY BY INHIBITING ITS ASSOCIATION WITH CELLS
Authors: SADLER IIJ SMITH DW SHEARMAN MS RAGAN CI TAILOR VJ POLLACK SJ
Citation: Iij. Sadler et al., SULFATED COMPOUNDS ATTENUATE BETA-AMYLOID TOXICITY BY INHIBITING ITS ASSOCIATION WITH CELLS, NeuroReport, 7(1), 1995, pp. 49-53
CHARACTERIZATION OF DELTA-SUBUNIT CONTAINING GABA(A) RECEPTORS FROM RAT-BRAIN
Authors: QUIRK K WHITING PJ RAGAN CI MCKERNAN RM
Citation: K. Quirk et al., CHARACTERIZATION OF DELTA-SUBUNIT CONTAINING GABA(A) RECEPTORS FROM RAT-BRAIN, European journal of pharmacology. Molecular pharmacology section, 290(3), 1995, pp. 175-181
CHARACTERIZATION OF STABLY EXPRESSED RECOMBINANT HUMAN N-METHYL-D-ASPARTATE RECEPTORS USING A CA-45(2-INFLUX ASSAY())
Authors: GRIMWOOD S GILBERT E MYERS J LEBOURDELLES B COCKETT W RAGAN CI WHITING PJ HUTSON PH
Citation: S. Grimwood et al., CHARACTERIZATION OF STABLY EXPRESSED RECOMBINANT HUMAN N-METHYL-D-ASPARTATE RECEPTORS USING A CA-45(2-INFLUX ASSAY()), British Journal of Pharmacology, 116, 1995, pp. 113-113
RELATIONSHIP BETWEEN INHIBITION OF CYCLIC-AMP PRODUCTION IN CHINESE-HAMSTER OVARY CELLS EXPRESSING THE RAT D-2(444) RECEPTOR AND ANTAGONISTAGONIST BINDING RATIOS
Authors: HARLEY EA MIDDLEMISS DN RAGAN CI
Citation: Ea. Harley et al., RELATIONSHIP BETWEEN INHIBITION OF CYCLIC-AMP PRODUCTION IN CHINESE-HAMSTER OVARY CELLS EXPRESSING THE RAT D-2(444) RECEPTOR AND ANTAGONISTAGONIST BINDING RATIOS, British Journal of Pharmacology, 115(7), 1995, pp. 1307-1313
INHIBITION OF PC12 CELL REDOX ACTIVITY IS A SPECIFIC, EARLY INDICATOROF THE MECHANISM OF BETA-AMYLOID-MEDIATED CELL-DEATH
Authors: SHEARMAN MS RAGAN CI IVERSEN LL
Citation: Ms. Shearman et al., INHIBITION OF PC12 CELL REDOX ACTIVITY IS A SPECIFIC, EARLY INDICATOROF THE MECHANISM OF BETA-AMYLOID-MEDIATED CELL-DEATH, Proceedings of the National Academy of Sciences of the United Statesof America, 91(4), 1994, pp. 1470-1474
MECHANISM OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM-THERAPY
Authors: POLLACK SJ ATACK JR KNOWLES MR MCALLISTER G RAGAN CI BAKER R FLETCHER SR IVERSEN LL BROUGHTON HB
Citation: Sj. Pollack et al., MECHANISM OF INOSITOL MONOPHOSPHATASE, THE PUTATIVE TARGET OF LITHIUM-THERAPY, Proceedings of the National Academy of Sciences of the United Statesof America, 91(13), 1994, pp. 5766-5770
ROLE OF THE BETA-SUBUNIT IN DETERMINING THE PHARMACOLOGY OF HUMAN GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTORS (VOL 44, PG 1211, 1993)
Authors: HADINGHAM KL WINGROVE PB WAFFORD KA BAIN C KEMP JA PALMER KJ WILSON AW WILCOX AS SIKELA JM RAGAN CI WHITING PJ
Citation: Kl. Hadingham et al., ROLE OF THE BETA-SUBUNIT IN DETERMINING THE PHARMACOLOGY OF HUMAN GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTORS (VOL 44, PG 1211, 1993), Molecular pharmacology, 46(1), 1994, pp. 211-211
GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTORS IN THE RAT-BRAIN CAN CONTAINBOTH GAMMA-2 AND GAMMA-3 SUBUNITS, BUT GAMMA-1 DOES NOT EXIST IN COMBINATION WITH ANOTHER GAMMA-SUBUNIT
Authors: QUIRK K GILLARD NP RAGAN CI WHITING PJ MCKERNAN RM
Citation: K. Quirk et al., GAMMA-AMINOBUTYRIC-ACID TYPE-A RECEPTORS IN THE RAT-BRAIN CAN CONTAINBOTH GAMMA-2 AND GAMMA-3 SUBUNITS, BUT GAMMA-1 DOES NOT EXIST IN COMBINATION WITH ANOTHER GAMMA-SUBUNIT, Molecular pharmacology, 45(6), 1994, pp. 1061-1070
EFFECTS OF L-690,488, A PRODRUG OF THE BISPHOSPHONATE INOSITOL MONOPHOSPHATASE INHIBITOR L-690,330, ON PHOSPHATIDYLINOSITOL CYCLE MARKERS
Authors: ATACK JR PRIOR AM FLETCHER SR QUIRK K MCKERNAN R RAGAN CI
Citation: Jr. Atack et al., EFFECTS OF L-690,488, A PRODRUG OF THE BISPHOSPHONATE INOSITOL MONOPHOSPHATASE INHIBITOR L-690,330, ON PHOSPHATIDYLINOSITOL CYCLE MARKERS, The Journal of pharmacology and experimental therapeutics, 270(1), 1994, pp. 70-76
MODEL OF SUBUNIT COMPOSITION OF GAMMA-AMINOBUTYRIC-ACID A RECEPTOR SUBTYPES EXPRESSED IN RAT CEREBELLUM WITH RESPECT TO THEIR ALPHA-SUBUNITAND GAMMA DELTA-SUBUNIT/
Authors: QUIRK K GILLARD NP RAGAN CI WHITING PJ MCKERNAN RM
Citation: K. Quirk et al., MODEL OF SUBUNIT COMPOSITION OF GAMMA-AMINOBUTYRIC-ACID A RECEPTOR SUBTYPES EXPRESSED IN RAT CEREBELLUM WITH RESPECT TO THEIR ALPHA-SUBUNITAND GAMMA DELTA-SUBUNIT/, The Journal of biological chemistry, 269(23), 1994, pp. 16020-16028
STRUCTURE AND PHARMACOLOGICAL CHARACTERIZATION OF DELTA-CONTAINING GABA(A) RECEPTORS IN RAT-BRAIN
Authors: QUIRK K GILLARD N WHITING PJ RAGAN CI MCKERNAN RM
Citation: K. Quirk et al., STRUCTURE AND PHARMACOLOGICAL CHARACTERIZATION OF DELTA-CONTAINING GABA(A) RECEPTORS IN RAT-BRAIN, British Journal of Pharmacology, 112, 1994, pp. 210000131-210000131
STRUCTURAL-ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES
Authors: BONE R FRANK L SPRINGER JP POLLACK SJ OSBORNE S ATACK JR KNOWLES MR MCALLISTER G RAGAN CI BROUGHTON HB BAKER R FLETCHER SR
Citation: R. Bone et al., STRUCTURAL-ANALYSIS OF INOSITOL MONOPHOSPHATASE COMPLEXES WITH SUBSTRATES, Biochemistry, 33(32), 1994, pp. 9460-9467
Risultati: 1-25 | 26-34