Authors:
Jones, DNC
Gartlon, J
Parker, F
Taylor, SG
Routledge, C
Hemmati, P
Munton, RP
Ashmeade, TE
Hatcher, JP
Johns, A
Porter, RA
Hagan, JJ
Hunter, AJ
Upton, N
Citation: Dnc. Jones et al., Effects of centrally administered orexin-1 and orexinA: a role for orexin-1 receptors in orexin-B-induced hyperactivity, PSYCHOPHAR, 153(2), 2001, pp. 210-218
Authors:
Bromidge, SM
Griffith, K
Heightman, TD
Jennings, A
King, FD
Moss, SF
Newman, H
Riley, G
Routledge, C
Serafinowska, HT
Thomas, DR
Citation: Sm. Bromidge et al., Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor, BIOORG MED, 11(21), 2001, pp. 2843-2846
Authors:
Bromidge, SM
Clarke, SE
Gager, T
Griffith, K
Jeffrey, P
Jennings, AJ
Joiner, GF
King, FD
Lovell, PJ
Moss, SF
Newman, H
Riley, G
Rogers, D
Routledge, C
Serafinowska, H
Smith, DR
Citation: Sm. Bromidge et al., Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134), BIOORG MED, 11(1), 2001, pp. 55-58
Authors:
Roberts, C
Hatcher, P
Hagan, JJ
Austin, NE
Jeffrey, P
Wyman, P
Gaster, LM
Routledge, C
Middlemiss, DN
Citation: C. Roberts et al., The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, onin vivo extracellular 5-HT levels in the freely-moving guinea-pig, N-S ARCH PH, 362(2), 2000, pp. 177-183
Authors:
Reavill, C
Taylor, SG
Wood, MD
Ashmeade, T
Austin, NE
Avenell, KY
Boyfield, I
Branch, CL
Cilia, J
Coldwell, MC
Hadley, MS
Hunter, AJ
Jeffrey, P
Jewitt, F
Johnson, CN
Jones, DNC
Medhurst, AD
Middlemiss, DN
Nash, DJ
Riley, GJ
Routledge, C
Stemp, G
Thewlis, KM
Trail, B
Vong, AKK
Hagan, JJ
Citation: C. Reavill et al., Pharmacological actions of a novel, high-affinity, and selective human dopamine D-3 receptor antagonist, SB-277011-A, J PHARM EXP, 294(3), 2000, pp. 1154-1165
Authors:
Stemp, G
Ashmeade, T
Branch, CL
Hadley, MS
Hunter, AJ
Johnson, CN
Nash, DJ
Thewlis, KM
Vong, AKK
Austin, NE
Jeffrey, P
Avenell, KY
Boyfield, I
Hagan, JJ
Middlemiss, DN
Reavill, C
Riley, GJ
Routledge, C
Wood, M
Citation: G. Stemp et al., Design and synthesis of trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A potent and selective dopamine D-3 receptor antagonist with high oral bioavailability and CNS penetration in the rat, J MED CHEM, 43(9), 2000, pp. 1878-1885
Authors:
Hirst, WD
Minton, JAL
Bromidge, SM
Moss, SF
Latter, AJ
Riley, G
Routledge, C
Middlemiss, DN
Price, GW
Citation: Wd. Hirst et al., Characterization of [I-125]-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue, BR J PHARM, 130(7), 2000, pp. 1597-1605
Authors:
Routledge, C
Bromidge, SM
Moss, SF
Price, GW
Hirst, W
Newman, H
Riley, G
Gager, T
Stean, T
Upton, N
Clarke, SE
Brown, AM
Middlemiss, DN
Citation: C. Routledge et al., Characterization of SB-271046: A potent, selective and orally active 5-HT6receptor antagonist, BR J PHARM, 130(7), 2000, pp. 1606-1612
Authors:
Shah, AJ
de Biasi, V
Taylor, SG
Roberts, C
Hemmati, P
Munton, R
West, A
Routledge, C
Camilleri, P
Citation: Aj. Shah et al., Development of a protocol for the automated analysis of amino acids in brain tissue samples and microdialysates, J CHROMAT B, 735(2), 1999, pp. 133-140
Authors:
Roberts, C
Boyd, DF
Middlemiss, DN
Routledge, C
Citation: C. Roberts et al., Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HTre-uptake site blockade, NEUROPHARM, 38(9), 1999, pp. 1409-1419
Authors:
Hagan, JJ
Leslie, RA
Patel, S
Evans, ML
Wattam, TA
Holmes, S
Benham, CD
Taylor, SG
Routledge, C
Hemmati, P
Munton, RP
Ashmeade, TE
Shah, AS
Hatcher, JP
Hatcher, PD
Jones, DNC
Smith, MI
Piper, DC
Hunter, AJ
Porter, RA
Upton, N
Citation: Jj. Hagan et al., Orexin A activates locus coeruleus cell firing and increases arousal in the rat, P NAS US, 96(19), 1999, pp. 10911-10916
Authors:
Bromidge, SM
Brown, AM
Clarke, SE
Dodgson, K
Gager, T
Grassam, HL
Jeffrey, PM
Joiner, GF
King, FD
Middlemiss, DN
Moss, SF
Newman, H
Riley, G
Routledge, C
Wyman, P
Citation: Sm. Bromidge et al., 5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046): A potent, selective, and orally bioavailable 5-HT6 receptor antagonist, J MED CHEM, 42(2), 1999, pp. 202-205