Authors:
Dinnell, K
Chicchi, GG
Dhar, MJ
Elliott, JM
Hollingworth, GJ
Kurtz, MM
Ridgill, MP
Rycroft, W
Tsao, KL
Williams, AR
Swain, CJ
Citation: K. Dinnell et al., 2-aryl indole NK1 receptor antagonists: Optimisation of the 2-aryl ring and the indole nitrogen substituent, BIOORG MED, 11(9), 2001, pp. 1237-1240
Authors:
Harrison, T
Owens, AP
Williams, BJ
Swain, CJ
Williams, A
Carlson, EJ
Rycroft, W
Tattersall, FD
Cascieri, MA
Chicchi, GG
Sadowski, S
Rupniak, NMJ
Hargreaves, RJ
Citation: T. Harrison et al., An orally active, water-soluble neurokinin-1 receptor antagonist suitable for both intravenous and oral clinical administration, J MED CHEM, 44(24), 2001, pp. 4296-4299
Authors:
Tattersall, FD
Rycroft, W
Cumberbatch, M
Mason, G
Tye, S
Williamson, DJ
Hale, JJ
Mills, SG
Finke, PE
MacCoss, M
Sadowski, S
Ber, E
Cascieri, M
Hill, RG
MacIntyre, DE
Hargreaves, RJ
Citation: Fd. Tattersall et al., The novel NK1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L758,298, inhibit acute and delayed cisplatin-inducedemesis in ferrets, NEUROPHARM, 39(4), 2000, pp. 652-663
Authors:
Hale, JJ
Mills, SG
MacCoss, M
Dorn, CP
Finke, PE
Budhu, RJ
Reamer, RA
Huskey, SEW
Luffer-Atlas, D
Dean, BJ
McGowan, EM
Feeney, WP
Chiu, SHL
Cascieri, MA
Chicchi, GG
Kurtz, MM
Sadowski, S
Ber, E
Tattersall, FD
Rupniak, NMJ
Williams, AR
Rycroft, W
Hargreaves, R
Metzger, JM
MacIntyre, DE
Citation: Jj. Hale et al., Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs, J MED CHEM, 43(6), 2000, pp. 1234-1241