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Results: 1-25 | 26-48
Results: 1-25/48
NUCLEOSIDES AND NUCLEOTIDES - 176 - 2'-DEOXY-2'-HYDROXYLAMINOCYLIDINE- A NEW ANTITUMOR NUCLEOSIDE THAT INHIBITS DNA-SYNTHESIS ALTHOUGH IT HAS A RIBONUCLEOSIDE STRUCTURE
Authors: OGAWA A SHUTO S INANAMI O KUWABARA M TANAKA M SASAKI T MATSUDA A
Citation: A. Ogawa et al., NUCLEOSIDES AND NUCLEOTIDES - 176 - 2'-DEOXY-2'-HYDROXYLAMINOCYLIDINE- A NEW ANTITUMOR NUCLEOSIDE THAT INHIBITS DNA-SYNTHESIS ALTHOUGH IT HAS A RIBONUCLEOSIDE STRUCTURE, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1913-1918
ANTITUMOR-ACTIVITY OF 5'-O-DIPALMITOYLPHOSPHATIDYL O-2'-DEOXY-1-BETA-D-ARABINO-PENTOFURANOSYLCYTOSINE IS ENHANCED BY LONG-CIRCULATING LIPOSOMALIZATION
Authors: ASAI T KUROHANE K SHUTO S AWANO H MATSUDA A TSUKADA H NAMBA Y OKADA S OKU N
Citation: T. Asai et al., ANTITUMOR-ACTIVITY OF 5'-O-DIPALMITOYLPHOSPHATIDYL O-2'-DEOXY-1-BETA-D-ARABINO-PENTOFURANOSYLCYTOSINE IS ENHANCED BY LONG-CIRCULATING LIPOSOMALIZATION, Biological & pharmaceutical bulletin, 21(7), 1998, pp. 766-771
STEREOSPECIFICITY OF 6'-C-NEPLANOCIN-A ANALOGS AS INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE ACTIVITY AND HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION
Authors: DAELEMANS D VANDAMME AM SHUTO S MATSUDA A DECLERCQ E
Citation: D. Daelemans et al., STEREOSPECIFICITY OF 6'-C-NEPLANOCIN-A ANALOGS AS INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE ACTIVITY AND HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION, Nucleosides & nucleotides, 17(1-3), 1998, pp. 479-486
SYNTHETIC STUDIES OF CARBOCYCLIC ANALOGS OF CYCLIC ADP-RIBOSE - FORMATION OF A CYCLIC DIMER, A 36-MEMBERED-RING PRODUCT, IN THE CONDENSATION REACTION OF AN -N-1-[5-(PHENYLTHIOPHOSPHORYL)CARBOCYCLIC-RIBOSYL] INOSINE 5'-PHOSPHATE DERIVATIVE MEDIATED BY AGNO3
Authors: SHUTO S SHIRATO M SUMITA Y UENO Y MATSUDA A
Citation: S. Shuto et al., SYNTHETIC STUDIES OF CARBOCYCLIC ANALOGS OF CYCLIC ADP-RIBOSE - FORMATION OF A CYCLIC DIMER, A 36-MEMBERED-RING PRODUCT, IN THE CONDENSATION REACTION OF AN -N-1-[5-(PHENYLTHIOPHOSPHORYL)CARBOCYCLIC-RIBOSYL] INOSINE 5'-PHOSPHATE DERIVATIVE MEDIATED BY AGNO3, Tetrahedron letters, 39(40), 1998, pp. 7341-7344
SYNTHESIS OF ROXYTETRAHYDROFURAN-4-YL]-ALPHA-D-GLUCO-PYRANOSIDE 3,4,3'-TRISPHOSPHATE AS A NOVEL POTENT IP3 RECEPTOR-LIGAND
Authors: TATANI K SHUTO S UENO Y MATSUDA A
Citation: K. Tatani et al., SYNTHESIS OF ROXYTETRAHYDROFURAN-4-YL]-ALPHA-D-GLUCO-PYRANOSIDE 3,4,3'-TRISPHOSPHATE AS A NOVEL POTENT IP3 RECEPTOR-LIGAND, Tetrahedron letters, 39(28), 1998, pp. 5065-5068
A NOVEL ALDOL-TYPE C-GLYCOSIDATION REACTION PROMOTED BY SAMARIUM DIIODIDE - REGIOSELECTIVE GENERATION OF A ULOSE-1-ENOLATE FROM PHENYL BENZYL-1-THIO-BETA-D-ARABINO-HEXOPYRANOSID-2-ULOSE
Authors: ICHIKAWA S SHUTO S MATSUDA A
Citation: S. Ichikawa et al., A NOVEL ALDOL-TYPE C-GLYCOSIDATION REACTION PROMOTED BY SAMARIUM DIIODIDE - REGIOSELECTIVE GENERATION OF A ULOSE-1-ENOLATE FROM PHENYL BENZYL-1-THIO-BETA-D-ARABINO-HEXOPYRANOSID-2-ULOSE, Tetrahedron letters, 39(25), 1998, pp. 4525-4528
NUCLEOSIDES AND NUCLEOTIDES - 173 - SYNTHESIS OF CYCLIC IDP-CARBOCYCLIC-RIBOSE, A STABLE MIMIC OF CYCLIC ADP-RIBOSE - SIGNIFICANT FACILITATION OF THE INTRAMOLECULAR CONDENSATION REACTION OF N-1-(CARBOCYCLIC-RIBOSYL)INOSINE 5',6''-DIPHOSPHATE DERIVATIVES BY AN 8-BROMO-SUBSTITUTION AT THE HYPOXANTHINE MOIETY
Authors: SHUTO S SHIRATO M SUMITA Y UENO Y MATSUDA A
Citation: S. Shuto et al., NUCLEOSIDES AND NUCLEOTIDES - 173 - SYNTHESIS OF CYCLIC IDP-CARBOCYCLIC-RIBOSE, A STABLE MIMIC OF CYCLIC ADP-RIBOSE - SIGNIFICANT FACILITATION OF THE INTRAMOLECULAR CONDENSATION REACTION OF N-1-(CARBOCYCLIC-RIBOSYL)INOSINE 5',6''-DIPHOSPHATE DERIVATIVES BY AN 8-BROMO-SUBSTITUTION AT THE HYPOXANTHINE MOIETY, Journal of organic chemistry, 63(6), 1998, pp. 1986-1994
NUCLEOSIDES AND NUCLEOTIDES - 174 - SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING [2-[[N-(2-AMINOETHYL)CARBAMOYL]OXY]ETHYL]THYMIDINE AND THEIR THERMAL-STABILITY AND NUCLEASE-RESISTANCE PROPERTIES
Authors: UENO Y NAGASAWA Y SUGIMOTO I KOJIMA N KANAZAKI M SHUTO S MATSUDA A
Citation: Y. Ueno et al., NUCLEOSIDES AND NUCLEOTIDES - 174 - SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING [2-[[N-(2-AMINOETHYL)CARBAMOYL]OXY]ETHYL]THYMIDINE AND THEIR THERMAL-STABILITY AND NUCLEASE-RESISTANCE PROPERTIES, Journal of organic chemistry, 63(5), 1998, pp. 1660-1667
STEREOSELECTIVE AND REGIOSELECTIVE INTRODUCTION OF 1-HYDROXYETHYL OR 2-HYDROXYETHYL GROUP VIA INTRAMOLECULAR RADICAL CYCLIZATION REACTION WITH A NOVEL SILICON-CONTAINING TETHER - AN EFFICIENT SYNTHESIS OF 4'ALPHA-BRANCHED 2'-DEOXYADENOSINES
Authors: SHUTO S KANAZAKI M ICHIKAWA S MINAKAWA N MATSUDA A
Citation: S. Shuto et al., STEREOSELECTIVE AND REGIOSELECTIVE INTRODUCTION OF 1-HYDROXYETHYL OR 2-HYDROXYETHYL GROUP VIA INTRAMOLECULAR RADICAL CYCLIZATION REACTION WITH A NOVEL SILICON-CONTAINING TETHER - AN EFFICIENT SYNTHESIS OF 4'ALPHA-BRANCHED 2'-DEOXYADENOSINES, Journal of organic chemistry, 63(3), 1998, pp. 746-754
ONE-POT CONVERSION OF ALPHA,BETA-UNSATURATED ALCOHOLS INTO THE CORRESPONDING CARBON-ELONGATED DIENES WITH A STABLE PHOSPHORUS YLIDE BAMNO4 SYSTEM - SYNTHESIS OF 6'-METHYLENE DERIVATIVES OF NEPLANOCIN-A AS POTENTIAL ANTIVIRAL NUCLEOSIDES - NEW NEPLANOCIN ANALOGS - 11
Authors: SHUTO S NIIZUMA S MATSUDA A
Citation: S. Shuto et al., ONE-POT CONVERSION OF ALPHA,BETA-UNSATURATED ALCOHOLS INTO THE CORRESPONDING CARBON-ELONGATED DIENES WITH A STABLE PHOSPHORUS YLIDE BAMNO4 SYSTEM - SYNTHESIS OF 6'-METHYLENE DERIVATIVES OF NEPLANOCIN-A AS POTENTIAL ANTIVIRAL NUCLEOSIDES - NEW NEPLANOCIN ANALOGS - 11, Journal of organic chemistry, 63(13), 1998, pp. 4489-4493
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CONFORMATIONALLY RESTRICTED ANALOGS OF MILNACIPRAN - INO-2-PROPYNYL]-N,N-DIETHYLCYCLOPROPANECARBOXAMIDE IS A NOVEL CLASS OF NMDA RECEPTOR-CHANNEL BLOCKER
Authors: SHUTO S ONO S IMOTO H YOSHII K MATSUDA A
Citation: S. Shuto et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CONFORMATIONALLY RESTRICTED ANALOGS OF MILNACIPRAN - INO-2-PROPYNYL]-N,N-DIETHYLCYCLOPROPANECARBOXAMIDE IS A NOVEL CLASS OF NMDA RECEPTOR-CHANNEL BLOCKER, Journal of medicinal chemistry, 41(18), 1998, pp. 3507-3514
NUCLEOSIDES AND NUCLEOTIDES - 175 - STRUCTURAL REQUIREMENTS OF THE SUGAR MOIETY FOR THE ANTITUMOR ACTIVITIES OF NEW NUCLEOSIDE ANTIMETABOLITES, 1-(3-C-ETHYNYL-BETA-D-RIBO-PENTOFURANOSYL)CYTOSINE AND 1-(3-C-ETHYNYL-BETA-D-RIBO-PENTOFURANOSYL)URACIL
Authors: HATTORI H NOZAWA E IINO T YOSHIMURA Y SHUTO S SHIMAMOTO Y NOMURA M FUKUSHIMA M TANAKA M SASAKI T MATSUDA A
Citation: H. Hattori et al., NUCLEOSIDES AND NUCLEOTIDES - 175 - STRUCTURAL REQUIREMENTS OF THE SUGAR MOIETY FOR THE ANTITUMOR ACTIVITIES OF NEW NUCLEOSIDE ANTIMETABOLITES, 1-(3-C-ETHYNYL-BETA-D-RIBO-PENTOFURANOSYL)CYTOSINE AND 1-(3-C-ETHYNYL-BETA-D-RIBO-PENTOFURANOSYL)URACIL, Journal of medicinal chemistry, 41(15), 1998, pp. 2892-2902
NEPLANOCIN-A, A POTENT INHIBITOR OF S-ADENOSYLHOMOCYSTEINE HYDROLASE,POTENTIATES GRANULOCYTIC DIFFERENTIATION OF ACUTE PROMYELOCYTIC LEUKEMIA-CELLS INDUCED BY ALL-TRANS-RETINOIC ACID
Authors: NIITSU N YAMAMOTOYAMAGUCHI Y KANATANI Y SHUTO S MATSUDA A UMEDA M HONMA Y
Citation: N. Niitsu et al., NEPLANOCIN-A, A POTENT INHIBITOR OF S-ADENOSYLHOMOCYSTEINE HYDROLASE,POTENTIATES GRANULOCYTIC DIFFERENTIATION OF ACUTE PROMYELOCYTIC LEUKEMIA-CELLS INDUCED BY ALL-TRANS-RETINOIC ACID, Experimental hematology, 25(12), 1997, pp. 1296-1303
NEW NEPLANOCIN ANALOGS .10. THE CONVERSION OF ADENOSINE TO NEPLANOCIN-A, A CARBOCYCLIC NUCLEOSIDE ANTIBIOTIC WITH POTENT ANTIVIRAL ACTIVITY
Authors: NIIZUMA S SHUTO S MATSUDA A
Citation: S. Niizuma et al., NEW NEPLANOCIN ANALOGS .10. THE CONVERSION OF ADENOSINE TO NEPLANOCIN-A, A CARBOCYCLIC NUCLEOSIDE ANTIBIOTIC WITH POTENT ANTIVIRAL ACTIVITY, Tetrahedron, 53(40), 1997, pp. 13621-13632
SYNTHESIS OF PSEUDO-PHOSPHOLIPIDS BY PHOS PHOLIPASE D-CATALYZED TRANSPHOSPHATIDYLATION
Authors: SHUTO S MATSUDA A
Citation: S. Shuto et A. Matsuda, SYNTHESIS OF PSEUDO-PHOSPHOLIPIDS BY PHOS PHOLIPASE D-CATALYZED TRANSPHOSPHATIDYLATION, Yuki Gosei Kagaku Kyokaishi, 55(3), 1997, pp. 207-216
A NEW METHOD FOR CONFORMATIONAL RESTRICTI ON BASED ON REPULSION BETWEEN ADJACENT SUBSTITUENTS ON A CYCLOPROPANE RING, AND ITS APPLICATION TO DESIGNING POTENT NMDA RECEPTOR ANTAGONISTS
Authors: SHUTO S MATSUDA A
Citation: S. Shuto et A. Matsuda, A NEW METHOD FOR CONFORMATIONAL RESTRICTI ON BASED ON REPULSION BETWEEN ADJACENT SUBSTITUENTS ON A CYCLOPROPANE RING, AND ITS APPLICATION TO DESIGNING POTENT NMDA RECEPTOR ANTAGONISTS, Yuki Gosei Kagaku Kyokaishi, 55(10), 1997, pp. 868-876
NUCLEOSIDES AND NUCLEOTIDES .163. SYNTHESIS OF 3'-BETA-BRANCHED URIDINE DERIVATIVES VIA INTRAMOLECULAR REFORMATSKY-TYPE REACTION PROMOTED BY SAMARIUM DIIODIDE
Authors: ICHIKAWA S SHUTO S MINAKAWA N MATSUDA A
Citation: S. Ichikawa et al., NUCLEOSIDES AND NUCLEOTIDES .163. SYNTHESIS OF 3'-BETA-BRANCHED URIDINE DERIVATIVES VIA INTRAMOLECULAR REFORMATSKY-TYPE REACTION PROMOTED BY SAMARIUM DIIODIDE, Journal of organic chemistry, 62(5), 1997, pp. 1368-1375
A NEW ENTRY TO 2-SUBSTITUTED PURINE NUCLEOSIDES BASED ON LITHIATION-MEDIATED STANNYL TRANSFER OF 6-CHLOROPURINE NUCLEOSIDES
Authors: KATO K HAYAKAWA H TANAKA H KUMAMOTO H SHINDOH S SHUTO S MIYASAKA T
Citation: K. Kato et al., A NEW ENTRY TO 2-SUBSTITUTED PURINE NUCLEOSIDES BASED ON LITHIATION-MEDIATED STANNYL TRANSFER OF 6-CHLOROPURINE NUCLEOSIDES, Journal of organic chemistry, 62(20), 1997, pp. 6833-6841
A NOVEL RING-ENLARGEMENT REACTION OF (3-OXA-2-SILACYCLOPENTYL)METHYL RADICALS INTO 4-OXA-3-SILACYCLOHEXYL RADICALS - STEREOSELECTIVE INTRODUCTION OF A HYDROXYETHYL GROUP VIA UNUSUAL 6-ENDO-CYCLIZATION PRODUCTSDERIVED FROM 3-OXA-4-SILAHEXENYL RADICALS AND ITS APPLICATION TO THE SYNTHESIS OF A 4'-ALPHA-BRANCHED NUCLEOSIDE
Authors: SHUTO S KANAZAKI M ICHIKAWA S MATSUDA A
Citation: S. Shuto et al., A NOVEL RING-ENLARGEMENT REACTION OF (3-OXA-2-SILACYCLOPENTYL)METHYL RADICALS INTO 4-OXA-3-SILACYCLOHEXYL RADICALS - STEREOSELECTIVE INTRODUCTION OF A HYDROXYETHYL GROUP VIA UNUSUAL 6-ENDO-CYCLIZATION PRODUCTSDERIVED FROM 3-OXA-4-SILAHEXENYL RADICALS AND ITS APPLICATION TO THE SYNTHESIS OF A 4'-ALPHA-BRANCHED NUCLEOSIDE, Journal of organic chemistry, 62(17), 1997, pp. 5676-5677
NUCLEOSIDES AND NUCLEOTIDES .156. CHELATION-CONTROLLED AND NONCHELATION-CONTROLLED DIASTEREOFACIAL SELECTIVE THIOPHENOL ADDITION-REACTIONS AT THE 2'-POSITION OF 2'-[(ALKOXYCARBONYL)METHYLENE]-2'-DEOXYURIDINES - CONVERSION OF Z)-2'-[(ALKOXYCARBONYL)METHYLENE]-2'-DEOXYURIDINES INTO THEIR (E)-ISOMERS
Authors: HASSAN AEA SHUTO S MATSUDA A
Citation: Aea. Hassan et al., NUCLEOSIDES AND NUCLEOTIDES .156. CHELATION-CONTROLLED AND NONCHELATION-CONTROLLED DIASTEREOFACIAL SELECTIVE THIOPHENOL ADDITION-REACTIONS AT THE 2'-POSITION OF 2'-[(ALKOXYCARBONYL)METHYLENE]-2'-DEOXYURIDINES - CONVERSION OF Z)-2'-[(ALKOXYCARBONYL)METHYLENE]-2'-DEOXYURIDINES INTO THEIR (E)-ISOMERS, Journal of organic chemistry, 62(1), 1997, pp. 11-17
NUCLEOSIDES AND NUCLEOTIDES .154. NEW NEPLANOCIN ANALOGS .8. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 6'-C-ETHYL, -ETHENYL, AND -ETHYNYL DERIVATIVES OF NEPLANOCIN A
Authors: SHUTO S OBARA T SAITO Y YAMASHITA K TANAKA M SASAKI T ANDREI G SNOECK R NEYTS J PADALKO E BALZARINI J DECLERCQ E MATSUDA A
Citation: S. Shuto et al., NUCLEOSIDES AND NUCLEOTIDES .154. NEW NEPLANOCIN ANALOGS .8. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 6'-C-ETHYL, -ETHENYL, AND -ETHYNYL DERIVATIVES OF NEPLANOCIN A, Chemical and Pharmaceutical Bulletin, 45(7), 1997, pp. 1163-1168
NEW NEPLANOCIN ANALOGS .9. A PRACTICAL PREPARATION OF (6'R)-6'-C-METHYLNEPLANOCIN-A (RMNPA), A POTENT ANTIVIRAL AGENT, AND THE DETERMINATION OF ITS 6'-CONFIGURATION - DIASTEREOSELECTIVE DEAMINATION BY ADENOSINE-DEAMINASE
Authors: SHUTO S OBARA T YAGINUMA S MATSUDA A
Citation: S. Shuto et al., NEW NEPLANOCIN ANALOGS .9. A PRACTICAL PREPARATION OF (6'R)-6'-C-METHYLNEPLANOCIN-A (RMNPA), A POTENT ANTIVIRAL AGENT, AND THE DETERMINATION OF ITS 6'-CONFIGURATION - DIASTEREOSELECTIVE DEAMINATION BY ADENOSINE-DEAMINASE, Chemical and Pharmaceutical Bulletin, 45(1), 1997, pp. 138-142
NUCLEOSIDES AND NUCLEOTIDES .150. ENZYMATIC-SYNTHESIS OF 5'-PHOSPHATIDYL DERIVATIVES OF -(2-C-CYANO-2-DEOXY-BETA-D-ARABINO-PENTOFURANOSYL) (CNDAC) AND THEIR NOTABLE ANTITUMOR EFFECTS IN MICE
Authors: SHUTO S AWANO H SHIMAZAKI N HANAOKA K MATSUDA A
Citation: S. Shuto et al., NUCLEOSIDES AND NUCLEOTIDES .150. ENZYMATIC-SYNTHESIS OF 5'-PHOSPHATIDYL DERIVATIVES OF -(2-C-CYANO-2-DEOXY-BETA-D-ARABINO-PENTOFURANOSYL) (CNDAC) AND THEIR NOTABLE ANTITUMOR EFFECTS IN MICE, Bioorganic & medicinal chemistry letters, 6(9), 1996, pp. 1021-1024
NUCLEOSIDES AND NUCLEOTIDES .155. SYNTHESIS, ANTITUMOR EFFECTS, AND POSSIBLE ENZYMATIC ACTIVATION MECHANISM OF 5'-PHOSPHATIDYL-2'-DEOXY-2'-METHYLENECYTIDINE (DMDC)
Authors: SHUTO S AWANO H FUJII A YAMAGAMI K MATSUDA A
Citation: S. Shuto et al., NUCLEOSIDES AND NUCLEOTIDES .155. SYNTHESIS, ANTITUMOR EFFECTS, AND POSSIBLE ENZYMATIC ACTIVATION MECHANISM OF 5'-PHOSPHATIDYL-2'-DEOXY-2'-METHYLENECYTIDINE (DMDC), Bioorganic & medicinal chemistry letters, 6(18), 1996, pp. 2177-2182
THE FIAU DERIVATIVE (2'S)-2'-DEOXY-2'-C-METHYL-5-IODOURIDINE (SMIU) IS A NOVEL, LESS CYTOTOXIC AND POTENT ANTI-HSV AND ANTI-VZV AGENT
Authors: KIRA T AWANO H SHUTO S MATSUDA A BABA M KONNO K SHIGETA S
Citation: T. Kira et al., THE FIAU DERIVATIVE (2'S)-2'-DEOXY-2'-C-METHYL-5-IODOURIDINE (SMIU) IS A NOVEL, LESS CYTOTOXIC AND POTENT ANTI-HSV AND ANTI-VZV AGENT, Antiviral chemistry & chemotherapy, 7(4), 1996, pp. 209-212
Risultati: 1-25 | 26-48