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Results: 1-25 | 26-42
Results: 1-25/42
EXPLORATION OF THE IMPORTANCE OF THE P-2-P-3 -NHCO-MOIETY IN A POTENTDIPEPTIDE OR TRIPEPTIDE INHIBITOR OF CALPAIN-I - INSIGHTS INTO THE DEVELOPMENT OF NONPEPTIDIC INHIBITORS OF CALPAIN-I
Authors: CHATTERJEE S IQBAL M MALLYA S SENADHI SE OKANE TM MCKENNA BA BOZYCZKOCOYNE D KAUER JC SIMAN R MALLAMO JP
Citation: S. Chatterjee et al., EXPLORATION OF THE IMPORTANCE OF THE P-2-P-3 -NHCO-MOIETY IN A POTENTDIPEPTIDE OR TRIPEPTIDE INHIBITOR OF CALPAIN-I - INSIGHTS INTO THE DEVELOPMENT OF NONPEPTIDIC INHIBITORS OF CALPAIN-I, Bioorganic & medicinal chemistry, 6(5), 1998, pp. 509-522
TURNOVER OF AMYLOID BETA-PROTEIN IN GENE-TARGETED MOUSE-BRAIN AND ACUTE REDUCTION OF ITS LEVEL BY APP PROCESSING MODULATORS
Authors: SAVAGE MJ TRUSKO SP HOWLAND DS FLOOD DG REAUME AG SIMAN R SCOTT RW
Citation: Mj. Savage et al., TURNOVER OF AMYLOID BETA-PROTEIN IN GENE-TARGETED MOUSE-BRAIN AND ACUTE REDUCTION OF ITS LEVEL BY APP PROCESSING MODULATORS, European journal of neuroscience, 10, 1998, pp. 8204-8204
TURNOVER OF AMYLOID BETA-PROTEIN IN MOUSE-BRAIN AND ACUTE REDUCTION OF ITS LEVEL BY PHORBOL ESTER
Authors: SAVAGE MJ TRUSKO SP HOWLAND DS PINSKER LR MISTRETTA S REAUME AG GREENBERG BD SIMAN R SCOTT RW
Citation: Mj. Savage et al., TURNOVER OF AMYLOID BETA-PROTEIN IN MOUSE-BRAIN AND ACUTE REDUCTION OF ITS LEVEL BY PHORBOL ESTER, The Journal of neuroscience, 18(5), 1998, pp. 1743-1752
ROLE OF CYSTEINE PROTEASES IN NEURONAL CELL-DEATH INDUCED BY 3-NITROPROPIONIC ACID
Authors: PANG Z BOZYCZKOCOYNE D SIMAN R BONDADA V GEDDES JW
Citation: Z. Pang et al., ROLE OF CYSTEINE PROTEASES IN NEURONAL CELL-DEATH INDUCED BY 3-NITROPROPIONIC ACID, Journal of neurochemistry, 70, 1998, pp. 6-6
D-AMINO-ACID CONTAINING, HIGH-AFFINITY INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I
Authors: CHATTERJEE S GU ZQ DUNN D TAO M JOSEF K TRIPATHY R BIHOVSKY R SENADHI SE OKANE TM MCKENNA BA MALLYA S ATOR MA BOZYCZKOCOYNE D SIMAN R MALLAMO JP
Citation: S. Chatterjee et al., D-AMINO-ACID CONTAINING, HIGH-AFFINITY INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I, Journal of medicinal chemistry, 41(15), 1998, pp. 2663-2666
MODULATION OF SECRETED BETA-AMYLOID PRECURSOR PROTEIN AND AMYLOID-BETA PEPTIDE IN BRAIN BY CHOLESTEROL
Authors: HOWLAND DS TRUSKO SP SAVAGE MJ REAUME AG LANG DM HIRSCH JD MAEDA N SIMAN R GREENBERG BD SCOTT RM FLOOD DG
Citation: Ds. Howland et al., MODULATION OF SECRETED BETA-AMYLOID PRECURSOR PROTEIN AND AMYLOID-BETA PEPTIDE IN BRAIN BY CHOLESTEROL, The Journal of biological chemistry, 273(26), 1998, pp. 16576-16582
A SENSITIVE, CONTINUOUSLY RECORDING FLUOROGENIC ASSAY FOR CALPAIN
Authors: MALLYA SK MEYER S BOZYCZKOCOYNE D SIMAN R ATOR MA
Citation: Sk. Mallya et al., A SENSITIVE, CONTINUOUSLY RECORDING FLUOROGENIC ASSAY FOR CALPAIN, Biochemical and biophysical research communications (Print), 248(2), 1998, pp. 293-296
SUBSITE REQUIREMENTS FOR PEPTIDE ALDEHYDE INHIBITORS OF HUMAN CALPAIN-I
Authors: IQBAL M MESSINA PA FREED B DAS M CHATTERJEE S TRIPATHY R TAO M JOSEF KA DEMBOFSKY B DUNN D GRIFFITH E SIMAN R SENADHI SE BIAZZO W BOZYCZKOCOYNE D MEYER SL ATOR MA BIHOVSKY R
Citation: M. Iqbal et al., SUBSITE REQUIREMENTS FOR PEPTIDE ALDEHYDE INHIBITORS OF HUMAN CALPAIN-I, Bioorganic & medicinal chemistry letters, 7(5), 1997, pp. 539-544
NONPEPTIDIC INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I
Authors: CHATTERJEE S SENADHI S BOZYCZKOCOYNE D SIMAN R MALLAMO JP
Citation: S. Chatterjee et al., NONPEPTIDIC INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I, Bioorganic & medicinal chemistry letters, 7(3), 1997, pp. 287-290
A CALPAIN INHIBITOR ATTENUATES CORTICAL CYTOSKELETAL PROTEIN LOSS AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY IN THE RAT
Authors: POSMANTUR R KAMPFL A SIMAN R LIU SJ ZHAO X CLIFTON GL HAYES RL
Citation: R. Posmantur et al., A CALPAIN INHIBITOR ATTENUATES CORTICAL CYTOSKELETAL PROTEIN LOSS AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY IN THE RAT, Neuroscience, 77(3), 1997, pp. 875-888
HEPARIN PROMOTES BETA-SECRETASE CLEAVAGE OF THE ALZHEIMERS AMYLOID PRECURSOR PROTEIN
Authors: LEVEUGLE B DING W DURKIN JT MISTRETTA S EISLE J MATIC M SIMAN R GREENBERG BD FILLIT HM
Citation: B. Leveugle et al., HEPARIN PROMOTES BETA-SECRETASE CLEAVAGE OF THE ALZHEIMERS AMYLOID PRECURSOR PROTEIN, Neurochemistry international, 30(6), 1997, pp. 543-548
SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A SERIES OF POTENT FLUOROMETHYL KETONE INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I
Authors: CHATTERJEE S ATOR MA BOZYCZKOCOYNE D JOSEF K WELLS G TRIPATHY R IQBAL M BIHOVSKY R SENADHI SE MALLYA S OKANE T MCKENNA BA SIMAN R MALLAMO JP
Citation: S. Chatterjee et al., SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A SERIES OF POTENT FLUOROMETHYL KETONE INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I, Journal of medicinal chemistry, 40(23), 1997, pp. 3820-3828
POTENT ALPHA-KETOCARBONYL AND BORONIC ESTER DERIVED INHIBITORS OF PROTEASOME
Authors: IQBAL M CHATTERJEE S KAUER JC MALLAMO JP MESSINA PA REIBOLDT A SIMAN R
Citation: M. Iqbal et al., POTENT ALPHA-KETOCARBONYL AND BORONIC ESTER DERIVED INHIBITORS OF PROTEASOME, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 287-290
XANTHENE DERIVED POTENT NONPEPTIDIC INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I
Authors: CHATERJEE S IQBAL M KAUER JC MALLAMO JP SENADHI S MALLYA S BOZYCZKOCOYNE D SIMAN R
Citation: S. Chaterjee et al., XANTHENE DERIVED POTENT NONPEPTIDIC INHIBITORS OF RECOMBINANT HUMAN CALPAIN-I, Bioorganic & medicinal chemistry letters, 6(13), 1996, pp. 1619-1622
POTENT FLUOROMETHYL KETONE INHIBITORS OF RECOMBINANT HUMAN CALPAIN I+
Authors: CHATTERJEE S JOSEF K WELLS G IQBAL M BIHOVSKY R MALLAMO JP ATOR MA BOZYCZKOCOYNE D MALLYA S SENADHI S SIMAN R
Citation: S. Chatterjee et al., POTENT FLUOROMETHYL KETONE INHIBITORS OF RECOMBINANT HUMAN CALPAIN I+, Bioorganic & medicinal chemistry letters, 6(11), 1996, pp. 1237-1240
INCREASED EXPRESSION OF IL-1-BETA CONVERTING-ENZYME IN HIPPOCAMPUS AFTER ISCHEMIA - SELECTIVE LOCALIZATION IN MICROGLIA
Authors: BHAT RV DIROCCO R MARCY VR FLOOD DG ZHU Y DOBRZANSKI P SIMAN R SCOTT R CONTRERAS PC MILLER M
Citation: Rv. Bhat et al., INCREASED EXPRESSION OF IL-1-BETA CONVERTING-ENZYME IN HIPPOCAMPUS AFTER ISCHEMIA - SELECTIVE LOCALIZATION IN MICROGLIA, The Journal of neuroscience, 16(13), 1996, pp. 4146-4154
BIOLOGICALLY-ACTIVE MONOMERIC AND HETERODIMERIC RECOMBINANT HUMAN CALPAIN-I PRODUCED USING THE BACULOVIRUS EXPRESSION SYSTEM
Authors: MEYER SL BOZYCZKOCOYNE D MALLYA SK SPAIS CM BIHOVSKY R KAWOOYA JK LANG DM SCOTT RW SIMAN R
Citation: Sl. Meyer et al., BIOLOGICALLY-ACTIVE MONOMERIC AND HETERODIMERIC RECOMBINANT HUMAN CALPAIN-I PRODUCED USING THE BACULOVIRUS EXPRESSION SYSTEM, Biochemical journal, 314, 1996, pp. 511-519
DIFFUSE PLAQUES CONTAIN C-TERMINAL A-BETA(42) AND NOT A-BETA(40) - EVIDENCE FROM CATS AND DOGS
Authors: CUMMINGS BJ SATOU T HEAD E MILGRAM NW COLE GM SAVAGE MJ PODLISNY MB SELKOE DJ SIMAN R GREENBERG BD COTMAN CW
Citation: Bj. Cummings et al., DIFFUSE PLAQUES CONTAIN C-TERMINAL A-BETA(42) AND NOT A-BETA(40) - EVIDENCE FROM CATS AND DOGS, Neurobiology of aging, 17(4), 1996, pp. 653-659
APP TRANSGENESIS - APPROACHES TOWARD THE DEVELOPMENT OF ANIMAL-MODELSFOR ALZHEIMER-DISEASE NEUROPATHOLOGY
Authors: GREENBERG BD SAVAGE MJ HOWLAND DS ALI SM SIEDLAK SL PERRY G SIMAN R SCOTT RW
Citation: Bd. Greenberg et al., APP TRANSGENESIS - APPROACHES TOWARD THE DEVELOPMENT OF ANIMAL-MODELSFOR ALZHEIMER-DISEASE NEUROPATHOLOGY, Neurobiology of aging, 17(2), 1996, pp. 153-171
PROTEASOME INHIBITION ENHANCES THE STABILITY OF MOUSE CU ZN SUPEROXIDE-DISMUTASE WITH MUTATIONS LINKED TO FAMILIAL AMYOTROPHIC-LATERAL-SCLEROSIS/
Authors: HOFFMAN EK WILCOX HM SCOTT RW SIMAN R
Citation: Ek. Hoffman et al., PROTEASOME INHIBITION ENHANCES THE STABILITY OF MOUSE CU ZN SUPEROXIDE-DISMUTASE WITH MUTATIONS LINKED TO FAMILIAL AMYOTROPHIC-LATERAL-SCLEROSIS/, Journal of the neurological sciences, 139(1), 1996, pp. 15-20
PROLONGED CALPAIN-MEDIATED SPECTRIN BREAKDOWN OCCURS REGIONALLY FOLLOWING EXPERIMENTAL BRAIN INJURY IN THE RAT
Authors: SAATMAN KE BOZYCZKOCOYNE D MARCY V SIMAN R MCINTOSH TK
Citation: Ke. Saatman et al., PROLONGED CALPAIN-MEDIATED SPECTRIN BREAKDOWN OCCURS REGIONALLY FOLLOWING EXPERIMENTAL BRAIN INJURY IN THE RAT, Journal of neuropathology and experimental neurology, 55(7), 1996, pp. 850-860
ENHANCED AMYLOIDOGENIC PROCESSING OF THE BETA-AMYLOID PRECURSOR PROTEIN IN GENE-TARGETED MICE BEARING THE SWEDISH FAMILIAL ALZHEIMERS-DISEASE MUTATIONS AND A HUMANIZED A-BETA SEQUENCE
Authors: REAUME AG HOWLAND DS TRUSKO SP SAVAGE MJ LANG DM GREENBERG BD SIMAN R SCOTT RW
Citation: Ag. Reaume et al., ENHANCED AMYLOIDOGENIC PROCESSING OF THE BETA-AMYLOID PRECURSOR PROTEIN IN GENE-TARGETED MICE BEARING THE SWEDISH FAMILIAL ALZHEIMERS-DISEASE MUTATIONS AND A HUMANIZED A-BETA SEQUENCE, The Journal of biological chemistry, 271(38), 1996, pp. 23380-23388
METABOLISM OF THE SWEDISH AMYLOID PRECURSOR PROTEIN VARIANT IN NEURO2A (N2A) CELLS - EVIDENCE THAT CLEAVAGE AT THE BETA-SECRETASE SITE OCCURS IN THE GOLGI-APPARATUS
Authors: THINAKARAN G TEPLOW DB SIMAN R GREENBERG B SISODIA SS
Citation: G. Thinakaran et al., METABOLISM OF THE SWEDISH AMYLOID PRECURSOR PROTEIN VARIANT IN NEURO2A (N2A) CELLS - EVIDENCE THAT CLEAVAGE AT THE BETA-SECRETASE SITE OCCURS IN THE GOLGI-APPARATUS, The Journal of biological chemistry, 271(16), 1996, pp. 9390-9397
REGIONAL DISTRIBUTION AND TIME-COURSE OF CALPAIN ACTIVATION FOLLOWINGKAINATE-INDUCED SEIZURE ACTIVITY IN ADULT-RAT BRAIN
Authors: BI XN CHANG V SIMAN R TOCCO G BAUDRY M
Citation: Xn. Bi et al., REGIONAL DISTRIBUTION AND TIME-COURSE OF CALPAIN ACTIVATION FOLLOWINGKAINATE-INDUCED SEIZURE ACTIVITY IN ADULT-RAT BRAIN, Brain research, 726(1-2), 1996, pp. 98-108
ELEVATED A-BETA LEVELS IN ALZHEIMERS-DISEASE BRAIN ARE ASSOCIATED WITH SELECTIVE ACCUMULATION OF A-BETA(42) IN PARENCHYMAL AMYLOID PLAQUES AND BOTH A-BETA(40) AND A-BETA(42) IN CEREBROVASCULAR DEPOSITS
Authors: SAVAGE MJ KAWOOYA JK PINSKER LR EMMONS TL MISTRETTA S SIMAN R GREENBERG BD
Citation: Mj. Savage et al., ELEVATED A-BETA LEVELS IN ALZHEIMERS-DISEASE BRAIN ARE ASSOCIATED WITH SELECTIVE ACCUMULATION OF A-BETA(42) IN PARENCHYMAL AMYLOID PLAQUES AND BOTH A-BETA(40) AND A-BETA(42) IN CEREBROVASCULAR DEPOSITS, AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION, 2(4), 1995, pp. 234-240
Risultati: 1-25 | 26-42