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Results: 1-14 |
Results: 14
PYRROLOBENZIMIDAZOLES IN CANCER-TREATMENT
Authors: SKIBO EB
Citation: Eb. Skibo, PYRROLOBENZIMIDAZOLES IN CANCER-TREATMENT, Expert opinion on therapeutic patents, 8(6), 1998, pp. 673-701
DESIGN OF A CYCLOPROPYL QUINONE METHIDE REDUCTIVE ALKYLATING AGENT
Authors: OUYANG A SKIBO EB
Citation: A. Ouyang et Eb. Skibo, DESIGN OF A CYCLOPROPYL QUINONE METHIDE REDUCTIVE ALKYLATING AGENT, Journal of organic chemistry, 63(6), 1998, pp. 1893-1900
CHEMISTRY AND DNA ALKYLATION REACTIONS OF AZIRIDINYL QUINONES - DEVELOPMENT OF AN EFFICIENT ALKYLATING AGENT OF THE PHOSPHATE BACKBONE
Authors: SKIBO EB XING CG
Citation: Eb. Skibo et Cg. Xing, CHEMISTRY AND DNA ALKYLATION REACTIONS OF AZIRIDINYL QUINONES - DEVELOPMENT OF AN EFFICIENT ALKYLATING AGENT OF THE PHOSPHATE BACKBONE, Biochemistry (Easton), 37(43), 1998, pp. 15199-15213
STUDIES OF PYRROLO[1,2-A]BENZIMIDAZOLEQUINONE DT-DIAPHORASE SUBSTRATEACTIVITY, TOPOISOMERASE-II INHIBITION-ACTIVITY, AND DNA REDUCTIVE ALKYLATION
Authors: SKIBO EB GORDON S BESS L BORUAH R HEILEMAN MJ
Citation: Eb. Skibo et al., STUDIES OF PYRROLO[1,2-A]BENZIMIDAZOLEQUINONE DT-DIAPHORASE SUBSTRATEACTIVITY, TOPOISOMERASE-II INHIBITION-ACTIVITY, AND DNA REDUCTIVE ALKYLATION, Journal of medicinal chemistry, 40(9), 1997, pp. 1327-1339
THE ORGANIC-CHEMISTRY OF THE PYRROLO[1,2-ALPHA]BENZIMIDAZOLE ANTITUMOR AGENTS - AN EXAMPLE OF RATIONAL DRUG DESIGN
Authors: SKIBO EB ISLAM I SCHULZ WG ZHOU R BESS L BORUAH R
Citation: Eb. Skibo et al., THE ORGANIC-CHEMISTRY OF THE PYRROLO[1,2-ALPHA]BENZIMIDAZOLE ANTITUMOR AGENTS - AN EXAMPLE OF RATIONAL DRUG DESIGN, Synlett, (4), 1996, pp. 297-309
CHEMISTRY OF THE PYRROLO[1,2-A]BENZIMIDAZOLE ANTITUMOR AGENTS - INFLUENCE OF THE 7-SUBSTITUENT ON THE ABILITY TO ALKYLATE DNA AND INHIBIT TOPOISOMERASE-II
Authors: ZHOU R SKIBO EB
Citation: R. Zhou et Eb. Skibo, CHEMISTRY OF THE PYRROLO[1,2-A]BENZIMIDAZOLE ANTITUMOR AGENTS - INFLUENCE OF THE 7-SUBSTITUENT ON THE ABILITY TO ALKYLATE DNA AND INHIBIT TOPOISOMERASE-II, Journal of medicinal chemistry, 39(21), 1996, pp. 4321-4331
EVIDENCE FOR DNA PHOSPHATE BACKBONE ALKYLATION AND CLEAVAGE BY PYRROLO[1,2-ALPHA]BENZIMIDAZOLES - SMALL MOLECULES CAPABLE OF CAUSING BASE-PAIR-SPECIFIC PHOSPHODIESTER BOND HYDROLYSIS
Authors: SCHULZ WG NIEMAN RA SKIBO EB
Citation: Wg. Schulz et al., EVIDENCE FOR DNA PHOSPHATE BACKBONE ALKYLATION AND CLEAVAGE BY PYRROLO[1,2-ALPHA]BENZIMIDAZOLES - SMALL MOLECULES CAPABLE OF CAUSING BASE-PAIR-SPECIFIC PHOSPHODIESTER BOND HYDROLYSIS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(25), 1995, pp. 11854-11858
DETERMINATION OF THE PK(A) VALUES FOR THE MITOMYCIN-C REDOX COUPLE BYTITRATION, PH RATE PROFILES, AND NERNST-CLARK FITS - STUDIES OF METHANOL ELIMINATION, CARBOCATION FORMATION, AND THE CARBOCATION QUINONE METHIDE EQUILIBRIUM
Authors: BORUAH RC SKIBO EB
Citation: Rc. Boruah et Eb. Skibo, DETERMINATION OF THE PK(A) VALUES FOR THE MITOMYCIN-C REDOX COUPLE BYTITRATION, PH RATE PROFILES, AND NERNST-CLARK FITS - STUDIES OF METHANOL ELIMINATION, CARBOCATION FORMATION, AND THE CARBOCATION QUINONE METHIDE EQUILIBRIUM, Journal of organic chemistry, 60(7), 1995, pp. 2232-2243
PYRROLO[1,2-A]BENZIMIDAZOLE-BASED QUINONES AND IMINOQUINONES - THE ROLE OF THE 3-SUBSTITUENT ON CYTOTOXICITY
Authors: SCHULZ WG ISLAM I SKIBO EB
Citation: Wg. Schulz et al., PYRROLO[1,2-A]BENZIMIDAZOLE-BASED QUINONES AND IMINOQUINONES - THE ROLE OF THE 3-SUBSTITUENT ON CYTOTOXICITY, Journal of medicinal chemistry, 38(1), 1995, pp. 109-118
A COMPARISON OF THE CYTOTOXIC AND PHYSICAL-PROPERTIES OF AZIRIDINYL QUINONE DERIVATIVES BASED ON THE PYRROLO[1,2-A]BENZIMIDAZOLE AND PYRROLO[1,2-A]INDOLE RING-SYSTEMS
Authors: BORUAH RC SKIBO EB
Citation: Rc. Boruah et Eb. Skibo, A COMPARISON OF THE CYTOTOXIC AND PHYSICAL-PROPERTIES OF AZIRIDINYL QUINONE DERIVATIVES BASED ON THE PYRROLO[1,2-A]BENZIMIDAZOLE AND PYRROLO[1,2-A]INDOLE RING-SYSTEMS, Journal of medicinal chemistry, 37(11), 1994, pp. 1625-1631
STRUCTURE-ACTIVITY STUDIES OF BENZIMIDAZOLE-BASED DNA-CLEAVING AGENTS- COMPARISON OF BENZIMIDAZOLE, PYRROLOBENZIMIDAZOLE, AND TETRAHYDROPYRIDOBENZIMIDAZOLE ANALOGS
Authors: SKIBO EB ISLAM I HEILEMAN MJ SCHULZ WG
Citation: Eb. Skibo et al., STRUCTURE-ACTIVITY STUDIES OF BENZIMIDAZOLE-BASED DNA-CLEAVING AGENTS- COMPARISON OF BENZIMIDAZOLE, PYRROLOBENZIMIDAZOLE, AND TETRAHYDROPYRIDOBENZIMIDAZOLE ANALOGS, Journal of medicinal chemistry, 37(1), 1994, pp. 78-92
INOSINE MONOPHOSPHATE DEHYDROGENASE FROM PORCINE (SUS-SCROFA-DOMESTICA) THYMUS - PURIFICATION AND PROPERTIES
Authors: PUGH ME SKIBO EB
Citation: Me. Pugh et Eb. Skibo, INOSINE MONOPHOSPHATE DEHYDROGENASE FROM PORCINE (SUS-SCROFA-DOMESTICA) THYMUS - PURIFICATION AND PROPERTIES, Comparative biochemistry and physiology. B. Comparative biochemistry, 105(2), 1993, pp. 381-387
A MECHANISTIC STUDY OF 2-VINYLBENZIMIDAZOLE FORMATION FROM 2-(2'-HALOETHYL)BENZIMIDAZOLES - SYNTHESIS OF HIGHLY ELECTRON-RICH VINYLIC COMPOUNDS BY GENERAL BASE AND SPECIFIC ACID-GENERAL BASE CATALYSIS
Authors: BORUAH RC SKIBO EB
Citation: Rc. Boruah et Eb. Skibo, A MECHANISTIC STUDY OF 2-VINYLBENZIMIDAZOLE FORMATION FROM 2-(2'-HALOETHYL)BENZIMIDAZOLES - SYNTHESIS OF HIGHLY ELECTRON-RICH VINYLIC COMPOUNDS BY GENERAL BASE AND SPECIFIC ACID-GENERAL BASE CATALYSIS, Journal of organic chemistry, 58(27), 1993, pp. 7797-7803
PYRROLO[1,2-A]BENZIMIDAZOLE-BASED AZIRIDINYL QUINONES - A NEW CLASS OF DNA-CLEAVING AGENT EXHIBITING G-BASE AND A-BASE SPECIFICITY
Authors: SKIBO EB SCHULZ WG
Citation: Eb. Skibo et Wg. Schulz, PYRROLO[1,2-A]BENZIMIDAZOLE-BASED AZIRIDINYL QUINONES - A NEW CLASS OF DNA-CLEAVING AGENT EXHIBITING G-BASE AND A-BASE SPECIFICITY, Journal of medicinal chemistry, 36(21), 1993, pp. 3050-3055
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