Authors:
SPILLER DG
GILES RV
BROUGHTON CM
GRZYBOWSKI J
RUDDELL CJ
TIDD DM
CLARK RE
Citation: Dg. Spiller et al., THE INFLUENCE OF TARGET PROTEIN HALF-LIFE ON THE EFFECTIVENESS OF ANTISENSE OLIGONUCLEOTIDE ANALOG-MEDIATED BIOLOGIC RESPONSES, Antisense & nucleic acid drug development, 8(4), 1998, pp. 281-293
Authors:
GILES RV
SPILLER DG
GRZYBOWSKI J
CLARK RE
TIDD DM
Citation: Rv. Giles et al., SELECTING OPTIMAL OLIGONUCLEOTIDE COMPOSITION FOR MAXIMAL ANTISENSE EFFECT FOLLOWING STREPTOLYSIN O-MEDIATED DELIVERY INTO HUMAN LEUKEMIA-CELLS, Nucleic acids research, 26(7), 1998, pp. 1567-1575
Authors:
GILES RV
SPILLER DG
BROUGHTON CM
GRZYBOWSKI J
RUDDELL CJ
TIDD DM
CLARK RE
Citation: Rv. Giles et al., THE INFLUENCE OF TARGET PROTEIN HALF-LIFE ON THE EFFECTIVENESS OF ANTISENSE OLIGONUCLEOTIDES, British Journal of Haematology, 101, 1998, pp. 142-142
Authors:
GILES RV
SPILLER DG
GRZYBOWSKI J
TIDD DM
CLARK RE
Citation: Rv. Giles et al., COMPARISON OF STREPTOLYSIN-O PERMEABILIZATION, ELECTROPORATION AND LIPOPHILIC CONJUGATION FOR DELIVERING ANTISENSE OLIGONUCLEOTIDES TARGETING BCR-ABL, British Journal of Haematology, 101, 1998, pp. 143-143
Authors:
CLARK RE
SPILLER DG
BROUGHTON CM
GRZYBOWSKI J
PENDER N
BRAMMER C
TIDD DM
Citation: Re. Clark et al., ANTISENSE OLIGONUCLEOTIDES TARGETING BCR-ABL FOR PURGING AUTOGRAFTS IN CHRONIC MYELOID-LEUKEMIA, British Journal of Haematology, 101, 1998, pp. 275-275
Authors:
SPILLER DG
GILES RV
GRZYBOWSKI J
TIDD DM
CLARK RE
Citation: Dg. Spiller et al., IMPROVING THE INTRACELLULAR DELIVERY AND MOLECULAR EFFICACY OF ANTISENSE OLIGONUCLEOTIDES IN CHRONIC MYELOID-LEUKEMIA CELLS - A COMPARISON OF STREPTOLYSIN-O PERMEABILIZATION, ELECTROPORATION, AND LIPOPHILIC CONJUGATION, Blood, 91(12), 1998, pp. 4738-4746
Authors:
BROUGHTON CM
SPILLER DG
PENDER N
KOMOROVSKAYA M
GRZYBOWSKI J
GILES RV
TIDD DM
CLARK RE
Citation: Cm. Broughton et al., PRECLINICAL STUDIES OF STREPTOLYSIN-O IN ENHANCING ANTISENSE OLIGONUCLEOTIDE UPTAKE IN HARVESTS FROM CHRONIC MYELOID-LEUKEMIA PATIENTS, Leukemia, 11(9), 1997, pp. 1435-1441
Citation: Rv. Giles et al., ENHANCED ANTISENSE EFFECTS RESULTING FROM AN IMPROVED STREPTOLYSIN-O PROTOCOL FOR OLIGODEOXYNUCLEOTIDE DELIVERY INTO HUMAN LEUKEMIA-CELLS, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1155-1163
Authors:
CLARK RE
GRZYBOWSKI J
PENDER N
SPILLER DG
BROUGHTON CM
BRAMMER C
TIDD DM
Citation: Re. Clark et al., TRANSPLANTATION OF ANTISENSE OLIGONUCLEOTIDE (ODN) PURGED AUTOGRAFTS IN CHRONIC MYELOID-LEUKEMIA (CML), Experimental hematology, 25(8), 1997, pp. 187-187
Authors:
CLARK RE
GRZYBOWSKI J
GILES RV
SPILLER DG
TIDD DM
Citation: Re. Clark et al., IMPROVING THE MOLECULAR EFFICACY OF ANTISENSE OLIGONUCLEOTIDES (ODN) IN CHRONIC MYELOID-LEUKEMIA, Experimental hematology, 25(8), 1997, pp. 573-573
Citation: Re. Clark et al., EFFECT OF CONJUGATES ON ANTISENSE OLIGONUCLEOTIDE UPTAKE INTO CHRONICMYELOID-LEUKEMIA CELLS, Blood, 88(10), 1996, pp. 3513-3513
Authors:
CLARK RE
BROUGHTON CM
SPILLER DG
PENDER N
KOMOROVSKAYA M
TIDD DM
Citation: Re. Clark et al., PRECLINICAL STUDIES OF STREPTOLYSIN-O IN ENHANCING ANTISENSE OLIGONUCLEOTIDE UPTAKE IN HARVESTS FROM CHRONIC MYELOID-LEUKEMIA PATIENTS, Blood, 88(10), 1996, pp. 3915-3915
Citation: Dg. Spiller et Dm. Tidd, NUCLEAR DELIVERY OF ANTISENSE OLIGODEOXYNUCLEOTIDES THROUGH REVERSIBLE PERMEABILIZATION OF HUMAN LEUKEMIA-CELLS WITH STREPTOLYSIN-O, Antisense research and development, 5(1), 1995, pp. 13-21
Citation: Rv. Giles et al., DETECTION OF RIBONUCLEASE H-GENERATED MESSENGER-RNA FRAGMENTS IN HUMAN LEUKEMIA-CELLS FOLLOWING REVERSIBLE MEMBRANE PERMEABILIZATION IN THEPRESENCE OF ANTISENSE OLIGODEOXYNUCLEOTIDES, Antisense research and development, 5(1), 1995, pp. 23-31
Authors:
GILES RV
RUDDELL CJ
SPILLER DG
GREEN JA
TIDD DM
Citation: Rv. Giles et al., SINGLE-BASE DISCRIMINATION FOR RIBONUCLEASE H-DEPENDENT ANTISENSE EFFECTS WITHIN INTACT HUMAN LEUKEMIA-CELLS, Nucleic acids research, 23(6), 1995, pp. 954-961
Citation: Re. Clark et al., EFFECT OF CHIMERIC AND CONVENTIONALLY LINKED ANTISENSE OLIGONUCLEOTIDES ON BCR-ABL EXPRESSION IN INTACT CHRONIC MYELOID-LEUKEMIA CELLS, Experimental hematology, 23(8), 1995, pp. 906-906
Authors:
GILES RV
SPILLER DG
GREEN JA
CLARK RE
TIDD DM
Citation: Rv. Giles et al., OPTIMIZATION OF ANTISENSE OLIGODEOXYNUCLEOTIDE STRUCTURE FOR TARGETING BCR-ABL MESSENGER-RNA, Blood, 86(2), 1995, pp. 744-754
Citation: Rv. Giles et al., CHIMERIC OLIGODEOXYNUCLEOTIDE ANALOGS - ENHANCED CELL UPTAKE OF STRUCTURES WHICH DIRECT RIBONUCLEASE-H WITH HIGH SPECIFICITY, Anti-cancer drug design, 8(1), 1993, pp. 33-51