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Results: 1-11 |
Results: 11
NONPEPTIDIC HIV PROTEASE INHIBITORS - C-2-SYMMETRY-BASED DESIGN OF BIS-SULFONAMIDE DIHYDROPYRONES
Authors: JANAKIRAMAN MN WATENPAUGH KD TOMICH PK CHONG KT TURNER SR TOMMASI RA THAISRIVONGS S STROHBACH JW
Citation: Mn. Janakiraman et al., NONPEPTIDIC HIV PROTEASE INHIBITORS - C-2-SYMMETRY-BASED DESIGN OF BIS-SULFONAMIDE DIHYDROPYRONES, Bioorganic & medicinal chemistry letters, 8(10), 1998, pp. 1237-1242
TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS
Authors: TURNER SR STROHBACH JW TOMMASI RA ARISTOFF PA JOHNSON PD SKULNICK HI DOLAK LA SEEST EP TOMICH PK BOHANAN MJ HORNG MM LYNN JC CHONG KT HINSHAW RR WATENPAUGH KD JANAKIRAMAN MN THAISRIVONGS S
Citation: Sr. Turner et al., TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS, Journal of medicinal chemistry, 41(18), 1998, pp. 3467-3476
SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SULFONE SUBSTITUTED HIV PROTEASE INHIBITORS
Authors: SCHWARTZ TM BUNDY GL STROHBACH JW THAISRIVONGS S JOHNSON PD SKULNICK HI TOMICH PK LYNN JC CHONG KT HINSHAW RR RAUB TJ PADBURY GE TOTH LN
Citation: Tm. Schwartz et al., SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SULFONE SUBSTITUTED HIV PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 7(4), 1997, pp. 399-402
ASYMMETRIC SYNTHESES AND ABSOLUTE STEREOCHEMISTRY OF 5,6-DIHYDRO-ALPHA-PYRONES, A NEW CLASS OF POTENT HIV PROTEASE INHIBITORS
Authors: JUDGE TM PHILLIPS G MORRIS JK LOVASZ KD ROMINES KR LUKE GP TULINSKY J TUSTIN JM CHRUSCIEL RA DOLAK LA MIZSAK SA WATT W MORRIS J VANDERVELDE SL STROHBACH JW GAMMILL RB
Citation: Tm. Judge et al., ASYMMETRIC SYNTHESES AND ABSOLUTE STEREOCHEMISTRY OF 5,6-DIHYDRO-ALPHA-PYRONES, A NEW CLASS OF POTENT HIV PROTEASE INHIBITORS, Journal of the American Chemical Society, 119(15), 1997, pp. 3627-3628
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S ROMERO DL TOMMASI RA JANAKIRAMAN MN STROHBACH JW TURNER SR BILES C MORGE RR JOHNSON PD ARISTOFF PA TOMICH PK LYNN JC HORNG MM CHONG KT HINSHAW RR HOWE WJ FINZEL BC WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4630-4642
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S SKULNICK HI TURNER SR STROHBACH JW TOMMASI RA JOHNSON PD ARISTOFF PA JUDGE TM GAMMILL RB MORRIS JK ROMINES KR CHRUSCIEL RA HINSHAW RR CHONG KT TARPLEY WG POPPE SM SLADE DE LYNN JC HORNG MM TOMICH PK SEEST EP DOLAK LA HOWE WJ HOWARD GM SCHWENDE FJ TOTH LN PADBURY GE WILSON GJ SHIOU LH ZIPP GL WILKINSON KF RUSH BD RUWART MJ KOEPLINGER KA ZHAO ZY COLE S ZAYA RM KAKUK TJ JANAKIRAMAN MN WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
CYCLOALKYLPYRANONES AND CYCLOALKYLDIHYDROPYRONES AS HIV PROTEASE INHIBITORS - EXPLORING THE IMPACT OF RING SIZE ON STRUCTURE-ACTIVITY-RELATIONSHIPS
Authors: ROMINES KR MORRIS JK HOWE WJ TOMICH PK HORNG MM CHONG KT HINSHAW RR ANDERSON DJ STROHBACH JW TURNER SR MIZSAK SA
Citation: Kr. Romines et al., CYCLOALKYLPYRANONES AND CYCLOALKYLDIHYDROPYRONES AS HIV PROTEASE INHIBITORS - EXPLORING THE IMPACT OF RING SIZE ON STRUCTURE-ACTIVITY-RELATIONSHIPS, Journal of medicinal chemistry, 39(20), 1996, pp. 4125-4130
STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S WATENPAUGH KD HOWE WJ TOMICH PK DOLAK LA CHONG KT TOMICH CSC TOMASSELLI AG TURNER SR STROHBACH JW MULICHAK AM JANAKIRAMAN MN MOON JB LYNN JC HORNG MM HINSHAW RR CURRY KA ROTHROCK DJ
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 38(18), 1995, pp. 3624-3637
STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS
Authors: THAISRIVONGS S TOMICH PK WATENPAUGH KD CHONG KT HOWE WJ YANG CP STROHBACH JW TURNER SR MCGRATH JP BOHANON MJ LYNN JC MULICHAK AM SPINELLI PA HINSHAW RR PAGANO PJ MOON JB RUWART MJ WILKINSON KF RUSH BD ZIPP GL DALGA RJ SCHWENDE FJ HOWARD GM PADBURY GE TOTH LN ZHAO ZY KOEPLINGER KA KAKUK TJ COLE SL ZAYA RM PIPER RC JEFFREY P
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 37(20), 1994, pp. 3200-3204
INHIBITORS OF THE PROTEASE FROM HUMAN-IMMUNODEFICIENCY-VIRUS - SYNTHESIS, ENZYME-INHIBITION, AND ANTIVIRAL ACTIVITY OF A SERIES OF COMPOUNDS CONTAINING THE DIHYDROXYETHYLENE TRANSITION-STATE ISOSTERE
Authors: THAISRIVONGS S TURNER SR STROHBACH JW TENBRINK RE TARPLEY WG MCQUADE TJ HEINRIKSON RL TOMASSELLI AG HUI JO HOWE WJ
Citation: S. Thaisrivongs et al., INHIBITORS OF THE PROTEASE FROM HUMAN-IMMUNODEFICIENCY-VIRUS - SYNTHESIS, ENZYME-INHIBITION, AND ANTIVIRAL ACTIVITY OF A SERIES OF COMPOUNDS CONTAINING THE DIHYDROXYETHYLENE TRANSITION-STATE ISOSTERE, Journal of medicinal chemistry, 36(8), 1993, pp. 941-952
PEPTIDOMIMETIC HIV PROTEASE INHIBITORS - PHOSPHATE PRODRUGS WITH IMPROVED BIOLOGICAL-ACTIVITIES
Authors: CHONG KT RUWART MJ HINSHAW RR WILKINSON KF RUSH BD YANCEY MF STROHBACH JW THAISRIVONGS S
Citation: Kt. Chong et al., PEPTIDOMIMETIC HIV PROTEASE INHIBITORS - PHOSPHATE PRODRUGS WITH IMPROVED BIOLOGICAL-ACTIVITIES, Journal of medicinal chemistry, 36(17), 1993, pp. 2575-2577
Risultati: 1-11 |