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Results: 1-25/27
Authors:
Schramm, VL
Citation: Vl. Schramm, Transition state variation in enzymatic reactions, CURR OP C B, 5(5), 2001, pp. 556-563
Authors:
Kicska, GA
Long, L
Horig, H
Fairchild, C
Tyler, PC
Furneaux, RH
Schramm, VL
Kaufman, HL
Citation: Ga. Kicska et al., Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes, P NAS US, 98(8), 2001, pp. 4593-4598
Authors:
Schramm, VL
Imola, MJ
Citation: Vl. Schramm et Mj. Imola, Management of nasopharyngeal salivary gland malignancy, LARYNGOSCOP, 111(9), 2001, pp. 1533-1544
Authors:
Evans, GB
Furneaux, RH
Hutchison, TL
Kezar, HS
Morris, PE
Schramm, VL
Tyler, PC
Citation: Gb. Evans et al., Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins, J ORG CHEM, 66(17), 2001, pp. 5723-5730
Authors:
Fedorov, A
Shi, W
Kicska, G
Fedorov, E
Tyler, PC
Furneaux, RH
Hanson, JC
Gainsford, GJ
Larese, JZ
Schramm, VL
Almo, SC
Citation: A. Fedorov et al., Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis, BIOCHEM, 40(4), 2001, pp. 853-860
Authors:
Shi, WX
Tanaka, KSE
Crother, TR
Taylor, MW
Almo, SC
Schramm, VL
Citation: Wx. Shi et al., Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae, BIOCHEM, 40(36), 2001, pp. 10800-10809
Authors:
Basso, LA
Santos, DS
Shi, WX
Furneaux, RH
Tyler, PC
Schramm, VL
Blanchard, JS
Citation: La. Basso et al., Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts, BIOCHEM, 40(28), 2001, pp. 8196-8203
Authors:
Shi, WX
Basso, LA
Santos, DS
Tyler, PC
Furneaux, RH
Blanchard, JS
Almo, SC
Schramm, VL
Citation: Wx. Shi et al., Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces, BIOCHEM, 40(28), 2001, pp. 8204-8215
Authors:
Wang, F
Shi, WX
Nieves, E
Angeletti, RH
Schramm, VL
Grubmeyer, C
Citation: F. Wang et al., A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase, BIOCHEM, 40(27), 2001, pp. 8043-8054
Authors:
Tanaka, KSE
Chen, XY
Ishikawa, Y
Tyler, PC
Furneaux, RH
Schramm, VL
Citation: Kse. Tanaka et al., Ricin A-chain inhibitors resembling the oxacarbenium ion transition state, BIOCHEM, 40(23), 2001, pp. 6845-6851
Authors:
LoBrutto, R
Bandarian, V
Magnusson, OT
Chen, XY
Schramm, VL
Reed, GH
Citation: R. Lobrutto et al., 5 '-deoxyadenosine contacts the substrate radical intermediate in the active site of ethanolamine ammonia-lyase: H-2 and C-13 electron nuclear doubleresonance studies, BIOCHEM, 40(1), 2001, pp. 9-14
Authors:
Lewis, BE
Schramm, VL
Citation: Be. Lewis et Vl. Schramm, Conformational equilibrium isotope effects in glucose by C-13 NMR spectroscopy and computational studies, J AM CHEM S, 123(7), 2001, pp. 1327-1336
Authors:
Wang, F
Miles, RW
Kicska, G
Nieves, E
Schramm, VL
Angeletti, RH
Citation: F. Wang et al., Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange, PROTEIN SCI, 9(9), 2000, pp. 1660-1668
Authors:
Evans, GB
Furneaux, RH
Gainsford, GJ
Schramm, VL
Tyler, PC
Citation: Gb. Evans et al., Synthesis of transition state analogue inhibitors for purine nucleoside phosphorylase and N-riboside hydrolases, TETRAHEDRON, 56(19), 2000, pp. 3053-3062
Authors:
Braunheim, BB
Bagdassarian, CK
Schramm, VL
Schwartz, SD
Citation: Bb. Braunheim et al., Quantum neural networks can predict binding free energies for enzymatic inhibitors, INT J QUANT, 78(3), 2000, pp. 195-204
Authors:
Shi, WX
Munagala, NR
Wang, CC
Li, CM
Tyler, PC
Furneaux, RH
Grubmeyer, C
Schramm, VL
Almo, SC
Citation: Wx. Shi et al., Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at1.75 angstrom, BIOCHEM, 39(23), 2000, pp. 6781-6790
Authors:
Chen, XY
Berti, PJ
Schramm, VL
Citation: Xy. Chen et al., Ricin A-chain: Kinetic isotope effects and transition state structure withstem-loop RNA, J AM CHEM S, 122(8), 2000, pp. 1609-1617
Authors:
Sauve, AA
Deng, HT
Angeletti, RH
Schramm, VL
Citation: Aa. Sauve et al., A covalent intermediate in CD38 is responsible for ADP-ribosylation and cyclization reactions, J AM CHEM S, 122(33), 2000, pp. 7855-7859
Authors:
Chen, XY
Berti, PJ
Schramm, VL
Citation: Xy. Chen et al., Transition-state analysis for depurination of DNA by ricin A-chain, J AM CHEM S, 122(28), 2000, pp. 6527-6534
Authors:
Li, CM
Tyler, PC
Furneaux, RH
Kicska, G
Xu, YM
Grubmeyer, C
Girvin, ME
Schramm, VL
Citation: Cm. Li et al., Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases, NAT ST BIOL, 6(6), 1999, pp. 582-587
Authors:
Shi, WX
Li, CM
Tyler, PC
Furneaux, RH
Grubmeyer, C
Schramm, VL
Almo, SC
Citation: Wx. Shi et al., The 2.0 angstrom structure of human hypoxanthineguanine phosphoribosyltransferase in complex with a transition-state analog inhibitor, NAT ST BIOL, 6(6), 1999, pp. 588-593
Authors:
Furneaux, RH
Schramm, VL
Tyler, PC
Citation: Rh. Furneaux et al., Transition state analogue inhibitors of protozoan nucleoside hydrolases, BIO MED CH, 7(11), 1999, pp. 2599-2606
Authors:
Schramm, VL
Citation: Vl. Schramm, Enzymatic transition-state analysis and transition-state analogs, METH ENZYM, 308, 1999, pp. 301-355
Authors:
Shi, WX
Schramm, VL
Almo, SC
Citation: Wx. Shi et al., Nucleoside hydrolase from leishmania major - Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-angstrom crystal structure, J BIOL CHEM, 274(30), 1999, pp. 21114-21120
Authors:
Braunheim, BB
Miles, RW
Schramm, VL
Schwartz, SD
Citation: Bb. Braunheim et al., Prediction of inhibitor binding free energies by quantum neural networks. Nucleoside analogues binding to trypanosomal nucleoside hydrolase, BIOCHEM, 38(49), 1999, pp. 16076-16083