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Results: 1-20 |
Results: 20
A synthesis of the pyrano[3,2-b]pyridine ring system under mild conditions
Authors: Harikrishnan, LS Boehm, TL Showalter, HDH
Citation: Ls. Harikrishnan et al., A synthesis of the pyrano[3,2-b]pyridine ring system under mild conditions, SYN COMMUN, 31(4), 2001, pp. 519-525
A synthesis of the pyrano[3,2-b]pyridine ring system under mild conditions(vol 31, pg 519, 2001)
Authors: Harikrishnan, LS Boehm, TL Showalter, HDH
Citation: Ls. Harikrishnan et al., A synthesis of the pyrano[3,2-b]pyridine ring system under mild conditions(vol 31, pg 519, 2001), SYN COMMUN, 31(20), 2001, pp. 3205-3205
Tyrosine kinase inhibitors. 18. 6-substituted 4-anilinoquinazolines and 4-anilinopyrido [3,4-d]pyrimidines as soluble, irreversible inhibitors of theepidermal growth factor receptor
Authors: Smaill, JB Showalter, HDH Zhou, HR Bridges, AJ McNamara, DJ Fry, DW Nelson, JM Sherwood, V Vincent, PW Roberts, BJ Elliott, WL Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 18. 6-substituted 4-anilinoquinazolines and 4-anilinopyrido [3,4-d]pyrimidines as soluble, irreversible inhibitors of theepidermal growth factor receptor, J MED CHEM, 44(3), 2001, pp. 429-440
Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity
Authors: Schroeder, MC Hamby, JM Connolly, CJC Grohar, PJ Winters, RT Barvian, MR Moore, CW Boushelle, SL Crean, SM Kraker, AJ Driscoll, DL Vincent, PW Elliott, WL Lu, GH Batley, BL Dahring, TK Major, TC Panek, RL Doherty, AM Showalter, HDH
Citation: Mc. Schroeder et al., Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity, J MED CHEM, 44(12), 2001, pp. 1915-1926
Synthesis of 3,4-dihydro-1(2H)-isoquinolinones
Authors: Showalter, HDH Sercel, AD Stier, MA Turner, WR
Citation: Hdh. Showalter et al., Synthesis of 3,4-dihydro-1(2H)-isoquinolinones, J HETERO CH, 38(4), 2001, pp. 961-964
Synthesis of 7-substituted 3-aryl-1,6-naphthyridin-2-amines and 7-substituted 3-aryl-1,6-naphthyridin-2(1H)-ones via diazotization of 3-aryl-1,6-naphthyridine-2,7-diamines
Authors: Thompson, AM Showalter, HDH Denny, WA
Citation: Am. Thompson et al., Synthesis of 7-substituted 3-aryl-1,6-naphthyridin-2-amines and 7-substituted 3-aryl-1,6-naphthyridin-2(1H)-ones via diazotization of 3-aryl-1,6-naphthyridine-2,7-diamines, J CHEM S P1, (12), 2000, pp. 1843-1852
Synthesis of 4-(phenylamino)pyrimidine derivatives as ATP-competitive protein kinase inhibitors with potential for cancer chemotherapy
Authors: Rewcastle, GW Denny, WA Showalter, HDH
Citation: Gw. Rewcastle et al., Synthesis of 4-(phenylamino)pyrimidine derivatives as ATP-competitive protein kinase inhibitors with potential for cancer chemotherapy, CURR ORG CH, 4(7), 2000, pp. 679-706
Synthesis and reactivity of a solid-supported dialkoxybenzaldehyde with anextended spacer
Authors: Harikrishnan, LS Showalter, HDH
Citation: Ls. Harikrishnan et Hdh. Showalter, Synthesis and reactivity of a solid-supported dialkoxybenzaldehyde with anextended spacer, SYNLETT, (9), 2000, pp. 1339-1341
A novel synthesis of 2,3-disubstituted benzopyran-4-ones and application to the solid phase
Authors: Harikrishnan, LS Showalter, HDH
Citation: Ls. Harikrishnan et Hdh. Showalter, A novel synthesis of 2,3-disubstituted benzopyran-4-ones and application to the solid phase, TETRAHEDRON, 56(4), 2000, pp. 515-519
Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions
Authors: Smaill, JB Rewcastle, GW Loo, JA Greis, KD Chan, OH Reyner, EL Lipka, E Showalter, HDH Vincent, PW Elliott, WL Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions, J MED CHEM, 43(7), 2000, pp. 1380-1397
3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase
Authors: Thompson, AM Connolly, CJC Hamby, JM Boushelle, S Hartl, BG Amar, AM Kraker, AJ Driscoll, DL Steinkampf, RW Patmore, SJ Vincent, PW Roberts, BJ Elliott, WL Klohs, W Leopold, WR Showalter, HDH Denny, WA
Citation: Am. Thompson et al., 3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase, J MED CHEM, 43(22), 2000, pp. 4200-4211
Synthesis and structure-activity relationships of 7-substituted 3-(2,6-dichlorophenyl)-1,6-naphthyridin-2 (1H)-ones as selective inhibitors of pp60(c-src)
Authors: Thompson, AM Rewcastle, GW Boushelle, SL Hartl, BG Kraker, AJ Lu, GH Batley, BL Panek, RL Showalter, HDH Denny, WA
Citation: Am. Thompson et al., Synthesis and structure-activity relationships of 7-substituted 3-(2,6-dichlorophenyl)-1,6-naphthyridin-2 (1H)-ones as selective inhibitors of pp60(c-src), J MED CHEM, 43(16), 2000, pp. 3134-3147
Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]-pyrimidine-6-acrylamides bearing additional solubilizing functions(vol 43, pg 1380, 2000)
Authors: Smaill, JB Rewcastle, GW Bridges, AJ Zhou, HR Showalter, HDH Fry, DW Nelson, JM Sherwood, V Elliott, WL Vincent, PW DeJohn, DE Loo, JA Greis, KD Chan, OH Reyner, EL Lipka, E Denny, WA
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]-pyrimidine-6-acrylamides bearing additional solubilizing functions(vol 43, pg 1380, 2000), J MED CHEM, 43(16), 2000, pp. 3199-3199
Biochemical and cellular effects of c-Src kinase-selective pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors
Authors: Kraker, AJ Hartl, BG Amar, AM Barvian, MR Showalter, HDH Moore, CW
Citation: Aj. Kraker et al., Biochemical and cellular effects of c-Src kinase-selective pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors, BIOCH PHARM, 60(7), 2000, pp. 885-898
Small molecule inhibitors of tumor-promoted angiogenesis, including protein tyrosine kinase inhibitors
Authors: Hamby, JM Showalter, HDH
Citation: Jm. Hamby et Hdh. Showalter, Small molecule inhibitors of tumor-promoted angiogenesis, including protein tyrosine kinase inhibitors, PHARM THERA, 82(2-3), 1999, pp. 169-193
Development of polymer-supported benzotriazole as a novel traceless linkerfor solid-phase organic synthesis
Authors: Schiemann, K Showalter, HDH
Citation: K. Schiemann et Hdh. Showalter, Development of polymer-supported benzotriazole as a novel traceless linkerfor solid-phase organic synthesis, J ORG CHEM, 64(13), 1999, pp. 4972-4975
Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno [3,2-d]pyrimidines and pyrimido[5,4-b]- and -[4,5-b]indoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase
Authors: Showalter, HDH Bridges, AJ Zhou, HR Sercel, AD McMichael, A Fry, DW
Citation: Hdh. Showalter et al., Tyrosine kinase inhibitors. 16. 6,5,6-tricyclic benzothieno [3,2-d]pyrimidines and pyrimido[5,4-b]- and -[4,5-b]indoles as potent inhibitors of the epidermal growth factor receptor tyrosine kinase, J MED CHEM, 42(26), 1999, pp. 5464-5474
Structure-activity relationships for 5-substituted 1-phenylbenzimidazoles as selective inhibitors of the platelet-derived growth factor receptor
Authors: Palmer, BD Kraker, AJ Hartl, BG Panopoulos, AD Panek, RL Batley, BL Lu, GH Trumpp-Kallmeyer, S Showalter, HDH Denny, WA
Citation: Bd. Palmer et al., Structure-activity relationships for 5-substituted 1-phenylbenzimidazoles as selective inhibitors of the platelet-derived growth factor receptor, J MED CHEM, 42(13), 1999, pp. 2373-2382
Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d] pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor
Authors: Smaill, JB Palmer, BD Rewcastle, GW Denny, WA McNamara, DJ Dobrusin, EM Bridges, AJ Zhou, HR Showalter, HDH Winters, RT Leopold, WR Fry, DW Nelson, JM Slintak, V Elliot, WL Roberts, BJ Vincent, PW Patmore, SJ
Citation: Jb. Smaill et al., Tyrosine kinase inhibitors. 15. 4-(phenylamino)quinazoline and 4-(phenylamino)pyrido[d] pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor, J MED CHEM, 42(10), 1999, pp. 1803-1815
Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor
Authors: Palmer, BD Smaill, JB Boyd, M Boschelli, DH Doherty, AM Hamby, JM Khatana, SS Kramer, JB Kraker, AJ Panek, RL Lu, GH Dahring, TK Winters, RT Showalter, HDH Denny, WA
Citation: Bd. Palmer et al., Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor, J MED CHEM, 41(27), 1998, pp. 5457-5465
Risultati: 1-20 |