Citation: S. Shuto et al., Intracellular Ca2+-mobilizing adenine nucleotides. Synthesis and biological activity of cyclic ADP-carbocyclic-ribose and C-glycosidic analog of adenophostin A, NUCLEOS NUC, 20(4-7), 2001, pp. 461-470
Authors:
Fukuoka, M
Shuto, S
Minakawa, N
Ueno, Y
Matsuda, A
Citation: M. Fukuoka et al., Synthesis and biological activities of cyclic ADP-carbocyclic-ribose and its analogs, NUCLEOS NUC, 20(4-7), 2001, pp. 1355-1358
Citation: Y. Kazuta et al., The bisected s-trans conformation-controlled highly stereoselective addition of Grignard reagents to C-cyclopropylaldonitrone. An efficient synthesisof 1-phenyl-2-[(S)-1-aminoalkyl]-N,N-diethylcyclopropanecarboxamides, a new class of potent NMDA receptor antagonists, J CHEM S P1, (6), 2001, pp. 599-604
Authors:
Tateoka, R
Abe, H
Miyauchi, S
Shuto, S
Matsuda, A
Kobayashi, M
Miyazaki, K
Kamo, N
Citation: R. Tateoka et al., Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1), BIOCONJ CHE, 12(4), 2001, pp. 485-492
Citation: T. Kodama et al., An efficient method for the preparation of 1 'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: The first conversion of a natural nucleoside into 1 '-substituted ribonucleosides, CHEM-EUR J, 7(11), 2001, pp. 2332-2340
Authors:
Asai, T
Shuto, S
Matsuda, A
Kakiuchi, T
Ohba, H
Tsukada, H
Oku, N
Citation: T. Asai et al., Targeting and anti-tumor efficacy of liposomal 5 '-O-dipalmitoylphosphatidyl 2 '-C-cyano-2 '-deoxy-1-beta-D-arabino-pentofuranosylcytosine in mice lung bearing B16BL6 melanoma, CANCER LETT, 162(1), 2001, pp. 49-56
Citation: H. Abe et al., An efficient method for preparing fully O-silylated pyranoses conformationally restricted in the unusual C-1(4)-form, TETRAHEDR L, 42(35), 2001, pp. 6159-6161
Citation: S. Shuto et al., Reactions with a vinylsilyl group as a radical-acceptor tether: The stereoselective introduction of C2-units and the ring-enlargement reaction of (3-oxa-2-silacyclopentyl) methyl radicals into 4-oxa-3-silacyclohexyl radicalsvia a pentavalent silicon-bridging radical transition state, J SYN ORG J, 59(6), 2001, pp. 589-598
Authors:
Correa, V
Riley, AM
Shuto, S
Horne, G
Nerou, EP
Marwood, RD
Potter, BVL
Taylor, CW
Citation: V. Correa et al., Structural determinants of adenophostin A activity at inositol trisphosphate receptors, MOLEC PHARM, 59(5), 2001, pp. 1206-1215
Citation: S. Shuto et al., (1S,2R)-1-phenyl-2-[(S)-1-aminopropyl]-N,N-diethylcyclopropane-carboxamide(PPDC), a new class of NMDA-receptor antagonist: Molecular design by a novel conformational restriction strategy, JPN J PHARM, 85(3), 2001, pp. 207-213
Authors:
Uchino, S
Watanabe, W
Nakamura, T
Shuto, S
Kazuta, Y
Matsuda, A
Nakajima-Iijima, S
Kudo, Y
Kohsaka, S
Mishina, M
Citation: S. Uchino et al., Establishment of CHO cell lines expressing four N-methyl-D-aspartate receptor subtypes and characterization of a novel antagonist PPDC, FEBS LETTER, 506(2), 2001, pp. 117-122
Citation: H. Abe et al., Highly alpha- and beta-selective radical C-glycosylation reactions using acontrolling anomeric effect based on the conformational restriction strategy. A study on the conformation-anomeric effect-stereoselectivity relationship in anomeric radical reactions, J AM CHEM S, 123(48), 2001, pp. 11870-11882
Authors:
Shuto, S
Fukuoka, M
Manikowsky, A
Ueno, Y
Nakano, T
Kuroda, R
Kuroda, H
Matsuda, A
Citation: S. Shuto et al., Total synthesis of cyclic ADP-carbocyclic-ribose, a stable mimic of Ca2+-mobilizing second messenger cyclic ADP-ribose, J AM CHEM S, 123(36), 2001, pp. 8750-8759
Authors:
Sumita, Y
Shirato, M
Ueno, Y
Matsuda, A
Shuto, S
Citation: Y. Sumita et al., Nucleosides and nucleotides. 192. Toward the total synthesis of cyclic ADP-carbocyclic-ribose. Formation of the intramolecular pyrophosphate linkage by a conformation-restriction strategy in a syn-form using a halogen substitution at the 8-position of the adenine ring, NUCLEOS NUC, 19(1-2), 2000, pp. 175-187
Authors:
Shuto, S
Haramuishi, K
Fukuoka, M
Matsuda, A
Citation: S. Shuto et al., Synthesis of sugar-modified analogs of bredinin (mizoribine), a clinicallyuseful immunosuppressant, by a novel photochemical imidazole ring-cleavagereaction as the key step, J CHEM S P1, (21), 2000, pp. 3603-3609
Authors:
Kashiwayanagi, M
Tatani, K
Shuto, S
Matsuda, A
Citation: M. Kashiwayanagi et al., Inositol 1,4,5-trisphosphate and adenophostin analogues induce responses in turtle olfactory sensory neurons, EUR J NEURO, 12(2), 2000, pp. 606-612
Citation: Y. Kazuta et al., Highly stereoselective addition of Grignard reagents to C-cyclopropylnitrone via the bisected s-trans conformation. An efficient synthesis of PEDC, apotent NMDA receptor antagonist having a cyclopropane structure, TETRAHEDR L, 41(28), 2000, pp. 5373-5377
Authors:
Shuto, S
Terauchi, M
Yahiro, Y
Abe, H
Ichikawa, S
Matsuda, A
Citation: S. Shuto et al., Stereoselective synthesis of alpha and beta-C-glucosides via radical cyclization with an allylsilyl tether. Control of the stereoselectivity by changing the conformation of the pyranose ring, TETRAHEDR L, 41(21), 2000, pp. 4151-4155
Citation: T. Kodama et al., Nucleosides and nucleotides. Part 199 - Synthesis of a 1 '-alpha-phenylselenouridine derivative as a synthetic precursor for various 1 '-modified nucleosides, via enolization at the 1 '-position of 3 ',5 '-O-TIPDS-2 '-ketouridine, TETRAHEDR L, 41(19), 2000, pp. 3643-3646
Citation: H. Abe et al., Synthesis of the C-glycosidic analog of adenophostin A, a potent IP3 receptor agonist, using a temporary silicon-tethered radical coupling reaction as the key step, TETRAHEDR L, 41(14), 2000, pp. 2391-2394
Authors:
Sukeda, M
Shuto, S
Sugimoto, I
Ichikawa, S
Matsuda, A
Citation: M. Sukeda et al., Synthesis of pyrimidine 2 '-deoxy ribonucleosides branched at the 2 '-position via radical atom-transfer cyclization reaction with a vinylsilyl groupas a radical-acceptor tether, J ORG CHEM, 65(26), 2000, pp. 8988-8996
Authors:
Shuto, S
Yahiro, Y
Ichikawa, S
Matsuda, A
Citation: S. Shuto et al., Synthesis of 3,7-anhydro-D-glycero-D-ido-octitol 1,5,6-trisphosphate as anIP3 receptor ligand using a radical cyclization reaction with a vinylsilyltether as the key step. Conformational restriction strategy using steric repulsion between adjacent bulky protecting groups on a pyranose ring, J ORG CHEM, 65(18), 2000, pp. 5547-5557