Authors:
Nichols, CE
Cocklin, S
Dodds, A
Ren, J
Lamb, H
Hawkins, AR
Stammers, DK
Citation: Ce. Nichols et al., Expression, purification and crystallization of Aspergillus nidulans NmrA,a negative regulatory protein involved in nitrogen-metabolite repression, ACT CRYST D, 57, 2001, pp. 1722-1725
Authors:
Stammers, DK
Ren, J
Leslie, K
Nichols, CE
Lamb, HK
Cocklin, S
Dodds, A
Hawkins, AR
Citation: Dk. Stammers et al., The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases, EMBO J, 20(23), 2001, pp. 6619-6626
Citation: J. Lennerstrand et al., Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine, ANTIM AG CH, 45(7), 2001, pp. 2144-2146
Authors:
Lennerstrand, J
Hertogs, K
Stammers, DK
Larder, BA
Citation: J. Lennerstrand et al., Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type1 mutants, J VIROLOGY, 75(15), 2001, pp. 7202-7205
Authors:
Ren, J
Nichols, C
Bird, L
Chamberlain, P
Weaver, K
Short, S
Stuart, DI
Stammers, DK
Citation: J. Ren et al., Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors, J MOL BIOL, 312(4), 2001, pp. 795-805
Authors:
Chan, JH
Hong, JS
Hunter, RN
Orr, GF
Cowan, JR
Sherman, DB
Sparks, SM
Reitter, BE
Andrews, CW
Hazen, RJ
St Clair, M
Boone, LR
Ferris, RG
Creech, KL
Roberts, GB
Short, SA
Weaver, K
Ott, RJ
Ren, JS
Hopkins, A
Stuart, DI
Stammers, DK
Citation: Jh. Chan et al., 2-amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1, J MED CHEM, 44(12), 2001, pp. 1866-1882
Authors:
Zhang, ZH
Ren, JS
Stammers, DK
Baldwin, JE
Harlos, K
Schofield, CJ
Citation: Zh. Zhang et al., Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase, NAT ST BIOL, 7(2), 2000, pp. 127-133
Authors:
Ren, J
Milton, J
Weaver, KL
Short, SA
Stuart, DI
Stammers, DK
Citation: J. Ren et al., Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase, STRUCTURE, 8(10), 2000, pp. 1089-1094
Authors:
Ren, JS
Nichols, C
Bird, LE
Fujiwara, T
Sugimoto, H
Stuart, DI
Stammers, DK
Citation: Js. Ren et al., Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding, J BIOL CHEM, 275(19), 2000, pp. 14316-14320
Authors:
Larder, BA
Bloor, S
Kemp, SD
Hertogs, K
Desmet, RL
Miller, V
Sturmer, M
Staszewski, S
Ren, J
Stammers, DK
Stuart, DI
Pauwels, R
Citation: Ba. Larder et al., A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance, ANTIM AG CH, 43(8), 1999, pp. 1961-1967
Authors:
Hopkins, AL
Ren, JS
Tanaka, H
Baba, M
Okamato, M
Stuart, DI
Stammers, DK
Citation: Al. Hopkins et al., Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants, J MED CHEM, 42(22), 1999, pp. 4500-4505
Authors:
Ren, JS
Esnouf, RM
Hopkins, AL
Stuart, DI
Stammers, DK
Citation: Js. Ren et al., Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies, J MED CHEM, 42(19), 1999, pp. 3845-3851
Authors:
Stammers, DK
Achari, A
Somers, DO
Bryant, PK
Rosemond, J
Scott, DL
Champness, JN
Citation: Dk. Stammers et al., 2.0 angstrom X-ray structure of the ternary complex of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue, FEBS LETTER, 456(1), 1999, pp. 49-53