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Results: 1-20 |
Results: 20

Authors: Shi, DF Bradshaw, TD Chua, MS Westwell, AD Stevens, MFG
Citation: Df. Shi et al., Antitumour benzothiazoles. Part 15: The synthesis and physico-chemical properties of 2-(4-aminophenyl)benzothiazole sulfamate salt derivatives, BIOORG MED, 11(8), 2001, pp. 1093-1095

Authors: Bradshaw, TD Stevens, MFG Westwell, AD
Citation: Td. Bradshaw et al., The discovery of the potent and selective antitumour agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203) and related compounds, CURR MED CH, 8(2), 2001, pp. 203-210

Authors: Gowan, SM Heald, R Stevens, MFG Kelland, LR
Citation: Sm. Gowan et al., Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes, MOLEC PHARM, 60(5), 2001, pp. 981-988

Authors: Hutchinson, I Chua, MS Browne, HL Trapani, V Bradshaw, TD Westwell, AD Stevens, MFG
Citation: I. Hutchinson et al., Antitumor benzothiazoles. 14. Synthesis and in vitro biological propertiesof fluorinated 2-(4-aminophenyl)benzothiazoles, J MED CHEM, 44(9), 2001, pp. 1446-1455

Authors: Chan, DCM Laughton, CA Queener, SF Stevens, MFG
Citation: Dcm. Chan et al., Structural studies on bioactive compounds. 34. Design, synthesis, and biological evaluation of triazenyl-substituted pyrimethamine inhibitors of Pneumocystis carinii dihydrofolate reductase, J MED CHEM, 44(16), 2001, pp. 2555-2564

Authors: Arrowsmith, J Jennings, SA Langnel, DAF Wheelhouse, RT Stevens, MFG
Citation: J. Arrowsmith et al., Antitumour imidazotetrazines. Part 39. Synthesis of bis(imidazotetrazine)swith saturated spacer groups, J CHEM S P1, (24), 2000, pp. 4432-4438

Authors: Hannah, DR Sherer, EC Davies, RV Titman, RB Laughton, CA Stevens, MFG
Citation: Dr. Hannah et al., Structural studies on bioactive compounds. Part 29: Palladium catalysed arylations and alkynylations of sterically hindered immunomodulatory 2-amino-5-halo-4,6-(disubstituted)pyrimidines, BIO MED CH, 8(4), 2000, pp. 739-750

Authors: Wells, G Bradshaw, TD Diana, P Seaton, A Shi, DF Westwell, AD Stevens, MFG
Citation: G. Wells et al., Antitumour benzothiazoles. Part 10: The synthesis and antitumour activity of benzothiazole substituted quinol derivatives, BIOORG MED, 10(5), 2000, pp. 513-515

Authors: Palat, K Stevens, MFG
Citation: K. Palat et Mfg. Stevens, Structural studies on bioactive compounds. Part 33. Synthesis of 9-arylacridines by palladium-mediated couplings, J CHEM R-S, (3), 2000, pp. 136-137

Authors: Julino, M Lowe, PR Stevens, MFG
Citation: M. Julino et al., Structural studies on bioactive compounds. Part 31. Interaction of 9-azidoacridine and 1-morpholinocyclohexene: formation, decomposition and rearrangement of the intermediate 1,2,3-triazoline, J CHEM R-S, (2), 2000, pp. 74-75

Authors: Hutchinson, I Stevens, MFG Westwell, AD
Citation: I. Hutchinson et al., The regiospecific synthesis of 5-and 7-manosubstituted and 5,6-disubstituted 2-arylbenzothiazoles, TETRAHEDR L, 41(3), 2000, pp. 425-428

Authors: Wells, G Seaton, A Stevens, MFG
Citation: G. Wells et al., Structural studies on bioactive compounds. 32. Oxidation of tryphostin protein tyrosine kinase inhibitors with hypervalent iodine reagents, J MED CHEM, 43(8), 2000, pp. 1550-1562

Authors: Stanslas, J Hagan, DJ Ellis, MJ Turner, C Carmichael, J Ward, W Hammonds, TR Stevens, MFG
Citation: J. Stanslas et al., Antitumor polycyclic acridines. 7. Synthesis and biological properties of DNA affinic tetra- and pentacyclic acridines, J MED CHEM, 43(8), 2000, pp. 1563-1572

Authors: Chua, MS Kashiyama, E Bradshaw, TD Stinson, SF Brantley, E Sausville, EA Stevens, MFG
Citation: Ms. Chua et al., Role of CYP1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells, CANCER RES, 60(18), 2000, pp. 5196-5203

Authors: Bradshaw, TD Chua, MS Orr, S Matthews, CS Stevens, MFG
Citation: Td. Bradshaw et al., Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445), BR J CANC, 83(2), 2000, pp. 270-277

Authors: Cody, V Chan, D Galitsky, N Rak, D Luft, JR Pangborn, W Queener, SF Laughton, CA Stevens, MFG
Citation: V. Cody et al., Structural studies on bioactive compounds. 30. Crystal structure and molecular modeling studies on the Pneumocystis carinii dihydrofolate reductase cofactor complex with TAB, a highly selective antifolate, BIOCHEM, 39(13), 2000, pp. 3556-3564

Authors: Arrowsmith, J Missailidis, S Stevens, MFG
Citation: J. Arrowsmith et al., Antitumour imidazotetrazines. Part 37. Conjugation of the DNA major-groovealkylating imidazotetrazine mitozolomide to peptide motifs recognizing theminor groove, ANTI-CAN DR, 14(3), 1999, pp. 205-217

Authors: Chua, MS Shi, DF Wrigley, S Bradshaw, TD Hutchinson, I Shaw, PN Barrett, DA Stanley, LA Stevens, MFG
Citation: Ms. Chua et al., Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl)benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines, J MED CHEM, 42(3), 1999, pp. 381-392

Authors: Kashiyama, E Hutchinson, I Chua, MS Stinson, SF Phillips, LR Kaur, G Sausville, EA Bradshaw, TD Westwell, AD Stevens, MFG
Citation: E. Kashiyama et al., Antitumor benzothiazoles. 8. Synthesis, metabolic formation, and biological properties of the C- and N-oxidation products of antitumor 2-(4-aminophenyl)benzothiazoles, J MED CHEM, 42(20), 1999, pp. 4172-4184

Authors: Bostock-Smith, CE Gimenez-Arnau, E Missailidis, S Laughton, CA Stevens, MFG Searle, MS
Citation: Ce. Bostock-smith et al., Molecular recognition between a new pentacyclic acridinium salt and DNA sequences investigated by optical spectroscopic techniques, proton nuclear magnetic resonance spectroscopy, and molecular modeling, BIOCHEM, 38(21), 1999, pp. 6723-6731
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