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Results:
1-18
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Results: 18
Authors:
Steinmetzer, T
Schweinitz, A
Kunzel, S
Wikstrom, P
Hauptmann, J
Sturzebecher, J
Citation: T. Steinmetzer et al., Structure-activity relationships of new NAPAP-analogs, J ENZ INHIB, 16(3), 2001, pp. 241-249
Authors:
Steinmetzer, T
Hauptmann, J
Sturzebecher, J
Citation: T. Steinmetzer et al., Advances in the development of thrombin inhibitors, EXPERT OP I, 10(5), 2001, pp. 845-864
Authors:
Kamm, W
Hauptmann, J
Behrens, I
Sturzebecher, J
Dullweber, F
Gohlke, H
Stubbs, M
Klebe, G
Kissel, T
Citation: W. Kamm et al., Transport of peptidomimetic thrombin inhibitors with a 3-amidino-phenylalanine structure: Permeability and efflux mechanism in monolayers of a human intestinal cell line (Caco-2), PHARM RES, 18(8), 2001, pp. 1110-1118
Authors:
Dullweber, F
Stubbs, MT
Musil, D
Sturzebecher, J
Klebe, G
Citation: F. Dullweber et al., Factorising ligand affinity: A combined thermodynamic and crystallographicstudy of trypsin and thrombin inhibition, J MOL BIOL, 313(3), 2001, pp. 593-614
Authors:
Steinmetzer, T
Batdordshjin, M
Pineda, F
Seyfarth, L
Vogel, A
Reissmann, S
Hauptmann, J
Sturzebecher, J
Citation: T. Steinmetzer et al., New bivalent thrombin inhibitors with N-alpha(methyl)arginine at the P1-position, BIOL CHEM, 381(7), 2000, pp. 603-610
Authors:
Sperl, S
Bergner, A
Sturzebecher, J
Magdolen, V
Bode, W
Moroder, L
Citation: S. Sperl et al., Urethanyl-3-amidinophenylalanine derivatives as inhibitors of factor Xa. X-ray crystal structure of a trypsin/inhibitor complex and modeling studies, BIOL CHEM, 381(4), 2000, pp. 321-329
Authors:
Schmitt, M
Wilhelm, OG
Reuning, U
Kruger, A
Harbeck, N
Lengyel, E
Graeff, H
Gansbacher, B
Kessler, H
Burgle, M
Sturzebecher, J
Sperl, S
Magdolen, V
Citation: M. Schmitt et al., The urokinase plasminogen activator system as a novel target for tumour therapy, FIBRINOL PR, 14(2-3), 2000, pp. 114-132
Authors:
Sperl, S
Jacob, U
de Prada, NA
Sturzebecher, J
Wilhelm, OG
Bode, W
Magdolen, V
Huber, R
Moroder, L
Citation: S. Sperl et al., (4-Aminomethyl)phenylguanidine derivatives as nonpeptidic highly selectiveinhibitors of human urokinase, P NAS US, 97(10), 2000, pp. 5113-5118
Authors:
Zeslawska, E
Schweinitz, A
Karcher, A
Sondermann, P
Sperl, S
Sturzebecher, J
Jacob, U
Citation: E. Zeslawska et al., Crystals of the urokinase type plasminogen activator variant beta c-uPA incomplex with small molecule inhibitors open the way towards structure-based drug design, J MOL BIOL, 301(2), 2000, pp. 465-475
Authors:
Lauer, G
Sollberg, S
Cole, M
Flamme, I
Sturzebecher, J
Mann, K
Krieg, T
Eming, SA
Citation: G. Lauer et al., Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds, J INVES DER, 115(1), 2000, pp. 12-18
Authors:
Steinmetzer, T
Batdorsdhjin, M
Kleinwachter, P
Seyfarth, L
Greiner, G
Reissmann, S
Sturzebecher, J
Citation: T. Steinmetzer et al., New thrombin inhibitors based on D-Cha-Pro-derivatives, J ENZ INHIB, 14(3), 1999, pp. 203-216
Authors:
Sturzebecher, J
Vieweg, H
Steinmetzer, T
Schweinitz, A
Stubbs, MT
Renatus, M
Wikstrom, P
Citation: J. Sturzebecher et al., 3-amidinophenylalanine-based inhibitors of urokinase, BIOORG MED, 9(21), 1999, pp. 3147-3152
Authors:
Hauptmann, J
Sturzebecher, J
Citation: J. Hauptmann et J. Sturzebecher, Synthetic inhibitors of thrombin and factor Xa: From bench to bedside, THROMB RES, 93(5), 1999, pp. 203-241
Authors:
Sommerhoff, CP
Bode, W
Pereira, PJB
Stubbs, MT
Sturzebecher, J
Piechottka, GP
Matschiner, G
Bergner, A
Citation: Cp. Sommerhoff et al., The structure of the human beta II-tryptase tetramer: Fo(u)r better or worse, P NAS US, 96(20), 1999, pp. 10984-10991
Authors:
Bohm, M
Sturzebecher, J
Klebe, G
Citation: M. Bohm et al., Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin, and factor Xa, J MED CHEM, 42(3), 1999, pp. 458-477
Authors:
Steinmetzer, T
Renatus, M
Kunzel, S
Eichinger, A
Bode, W
Wikstrom, P
Hauptmann, J
Sturzebecher, J
Citation: T. Steinmetzer et al., Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalanines, EUR J BIOCH, 265(2), 1999, pp. 598-605
Authors:
Kolkhorst, V
Sturzebecher, J
Wiederanders, B
Citation: V. Kolkhorst et al., Inhibition of tumour cell invasion by protease inhibitors: correlation with the protease profile, J CANC RES, 124(11), 1998, pp. 598-606
Authors:
Renatus, M
Bode, W
Huber, R
Sturzebecher, J
Stubbs, MT
Citation: M. Renatus et al., Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: Implications for the inhibition of factor Xa, tPA, and urokinase, J MED CHEM, 41(27), 1998, pp. 5445-5456
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