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Results: 1-23 |
Results: 23
CONFORMATIONALLY CONSTRAINED INHIBITORS OF CASPASE-1 (INTERLEUKIN-1-BETA CONVERTING-ENZYME) AND OF THE HUMAN CED-3 HOMOLOG CASPASE-3 (CPP32, APOPAIN)
Authors: KARANEWSKY DS BAI X LINTON SD KREBS JF WU J PHAM B TOMASELLI KJ
Citation: Ds. Karanewsky et al., CONFORMATIONALLY CONSTRAINED INHIBITORS OF CASPASE-1 (INTERLEUKIN-1-BETA CONVERTING-ENZYME) AND OF THE HUMAN CED-3 HOMOLOG CASPASE-3 (CPP32, APOPAIN), Bioorganic & medicinal chemistry letters, 8(19), 1998, pp. 2757-2762
HUMAN IAP-LIKE PROTEIN REGULATES PROGRAMMED CELL-DEATH DOWNSTREAM OF BCL-X(L) AND CYTOCHROME-C
Authors: DUCKETT CS LI F WANG Y TOMASELLI KJ THOMPSON CB ARMSTRONG RC
Citation: Cs. Duckett et al., HUMAN IAP-LIKE PROTEIN REGULATES PROGRAMMED CELL-DEATH DOWNSTREAM OF BCL-X(L) AND CYTOCHROME-C, Molecular and cellular biology, 18(1), 1998, pp. 608-615
ACTIVATION AND CLEAVAGE OF CASPASE-3 IN APOPTOSIS INDUCED BY EXPERIMENTAL CEREBRAL-ISCHEMIA
Authors: NAMURA S ZHU JM FINK K ENDRES M SRINIVASAN A TOMASELLI KJ YUAN JY MOSKOWITZ MA
Citation: S. Namura et al., ACTIVATION AND CLEAVAGE OF CASPASE-3 IN APOPTOSIS INDUCED BY EXPERIMENTAL CEREBRAL-ISCHEMIA, The Journal of neuroscience, 18(10), 1998, pp. 3659-3668
2 CD95 (APO-1 FAS) SIGNALING PATHWAYS
Authors: SCAFFIDI C FULDA S SRINIVASAN A FRIESEN C LI F TOMASELLI KJ DEBATIN KM KRAMMER PH PETER ME
Citation: C. Scaffidi et al., 2 CD95 (APO-1 FAS) SIGNALING PATHWAYS, EMBO journal, 17(6), 1998, pp. 1675-1687
BCL-X(L) FUNCTIONS DOWNSTREAM OF CASPASE-8 TO INHIBIT FAS-NECROSIS-FACTOR AND TUMOR-NECROSIS-FACTOR RECEPTOR-1-INDUCED APOPTOSIS OF MCF7 BREAST-CARCINOMA CELLS
Authors: SRINIVASAN A LI F WONG A KODANDAPANI L SMIDT R KREBS JF FRITZ LC WU JC TOMASELLI KJ
Citation: A. Srinivasan et al., BCL-X(L) FUNCTIONS DOWNSTREAM OF CASPASE-8 TO INHIBIT FAS-NECROSIS-FACTOR AND TUMOR-NECROSIS-FACTOR RECEPTOR-1-INDUCED APOPTOSIS OF MCF7 BREAST-CARCINOMA CELLS, The Journal of biological chemistry, 273(8), 1998, pp. 4523-4529
INTERACTION OF THE BACULOVIRUS ANTI-APOPTOTIC PROTEIN P35 WITH CASPASES - SPECIFICITY, KINETICS, AND CHARACTERIZATION OF THE CASPASE P35 COMPLEX/
Authors: ZHOU Q KREBS JF SNIPAS SJ PRICE A ALNEMRI ES TOMASELLI KJ SALVESEN GS
Citation: Q. Zhou et al., INTERACTION OF THE BACULOVIRUS ANTI-APOPTOTIC PROTEIN P35 WITH CASPASES - SPECIFICITY, KINETICS, AND CHARACTERIZATION OF THE CASPASE P35 COMPLEX/, Biochemistry, 37(30), 1998, pp. 10757-10765
ACTIVATION OF THE CED3 ICE-RELATED PROTEASE CPP32 IN CEREBELLAR GRANULE NEURONS UNDERGOING APOPTOSIS BUT NOT NECROSIS/
Authors: ARMSTRONG RC AJA TJ HOANG KD GAUR S BAI X ALNEMRI ES LITWACK G KARANEWSKY DS FRITZ LC TOMASELLI KJ
Citation: Rc. Armstrong et al., ACTIVATION OF THE CED3 ICE-RELATED PROTEASE CPP32 IN CEREBELLAR GRANULE NEURONS UNDERGOING APOPTOSIS BUT NOT NECROSIS/, The Journal of neuroscience, 17(2), 1997, pp. 553-562
CPP32 ACTIVATION AND CLEAVAGE IN NEURONAL APOPTOSIS AFTER TRANSIENT FOCAL CEREBRAL-ISCHEMIA
Authors: FINK K NAMURA S ZHU J ENDRES M SRINIVASAN A TOMASELLI KJ YUAN J MOSKOWITZ MA
Citation: K. Fink et al., CPP32 ACTIVATION AND CLEAVAGE IN NEURONAL APOPTOSIS AFTER TRANSIENT FOCAL CEREBRAL-ISCHEMIA, Naunyn-Schmiedeberg's archives of pharmacology, 356(4), 1997, pp. 52-52
DEATH EFFECTOR DOMAIN-CONTAINING HERPESVIRUS AND POXVIRUS PROTEINS INHIBIT BOTH FAS-INDUCED AND TNFR1-INDUCED APOPTOSIS
Authors: BERTIN J ARMSTRONG RC OTTILIE S MARTIN DA WANG Y BANKS S WANG GH SENKEVICH TG ALNEMRI ES MOSS B LENARDO MJ TOMASELLI KJ COHEN JI
Citation: J. Bertin et al., DEATH EFFECTOR DOMAIN-CONTAINING HERPESVIRUS AND POXVIRUS PROTEINS INHIBIT BOTH FAS-INDUCED AND TNFR1-INDUCED APOPTOSIS, Proceedings of the National Academy of Sciences of the United Statesof America, 94(4), 1997, pp. 1172-1176
BOVINE HERPESVIRUS-4 BORFE2 PROTEIN INHIBITS FAS-INDUCED AND TUMOR-NECROSIS-FACTOR RECEPTOR-1-INDUCED APOPTOSIS AND CONTAINS DEATH EFFECTORDOMAINS SHARED WITH OTHER GAMMA-2 HERPESVIRUSES
Authors: WANG GH BERTIN J WANG Y MARTIN DA WANG J TOMASELLI KJ ARMSTRONG RC COHEN JI
Citation: Gh. Wang et al., BOVINE HERPESVIRUS-4 BORFE2 PROTEIN INHIBITS FAS-INDUCED AND TUMOR-NECROSIS-FACTOR RECEPTOR-1-INDUCED APOPTOSIS AND CONTAINS DEATH EFFECTORDOMAINS SHARED WITH OTHER GAMMA-2 HERPESVIRUSES, Journal of virology, 71(11), 1997, pp. 8928-8932
CELL-SPECIFIC INDUCTION OF APOPTOSIS BY MICROINJECTION OF CYTOCHROME-C - BCL-X(L) HAS ACTIVITY INDEPENDENT OF CYTOCHROME-C RELEASE
Authors: LI F SRINIVASAN A WANG Y ARMSTRONG RC TOMASELLI KJ FRITZ LC
Citation: F. Li et al., CELL-SPECIFIC INDUCTION OF APOPTOSIS BY MICROINJECTION OF CYTOCHROME-C - BCL-X(L) HAS ACTIVITY INDEPENDENT OF CYTOCHROME-C RELEASE, The Journal of biological chemistry, 272(48), 1997, pp. 30299-30305
FLAME-1, A NOVEL FADD-LIKE ANTI-APOPTOTIC MOLECULE THAT REGULATES FASTNFR1-INDUCED APOPTOSIS/
Authors: SRINIVASULA SM AHMAD M OTTILIE S BULLRICH F BANKS S WANG Y FERNANDESALNEMRI T CROCE CM LITWACK G TOMASELLI KJ ARMSTRONG RC ALNEMRI ES
Citation: Sm. Srinivasula et al., FLAME-1, A NOVEL FADD-LIKE ANTI-APOPTOTIC MOLECULE THAT REGULATES FASTNFR1-INDUCED APOPTOSIS/, The Journal of biological chemistry, 272(30), 1997, pp. 18542-18545
IDENTIFICATION OF THE MDM2 ONCOPROTEIN AS A SUBSTRATE FOR CPP32-LIKE APOPTOTIC PROTEASES
Authors: ERHARDT P TOMASELLI KJ COOPER GM
Citation: P. Erhardt et al., IDENTIFICATION OF THE MDM2 ONCOPROTEIN AS A SUBSTRATE FOR CPP32-LIKE APOPTOTIC PROTEASES, The Journal of biological chemistry, 272(24), 1997, pp. 15049-15052
STRUCTURE OF RECOMBINANT HUMAN CPP32 IN COMPLEX WITH THE TETRAPEPTIDEACETYL-ASP-VAL-ALA-ASP FLUOROMETHYL KETONE
Authors: MITTL PRE DIMARCO S KREBS JF BAI X KARANEWSKY DS PRIESTLE JP TOMASELLI KJ GRUTTER MG
Citation: Pre. Mittl et al., STRUCTURE OF RECOMBINANT HUMAN CPP32 IN COMPLEX WITH THE TETRAPEPTIDEACETYL-ASP-VAL-ALA-ASP FLUOROMETHYL KETONE, The Journal of biological chemistry, 272(10), 1997, pp. 6539-6547
IN-VITRO ACTIVATION OF CPP32 AND MCH3 BY MCH4, A NOVEL HUMAN APOPTOTIC CYSTEINE PROTEASE CONTAINING 2 FADD-LIKE DOMAINS
Authors: FERNANDESALNEMRI T ARMSTRONG RC KREBS J SRINIVASULA SM WANG L BULLRICH F FRITZ LC TRAPANI JA TOMASELLI KJ LITWACK G ALNEMRI ES
Citation: T. Fernandesalnemri et al., IN-VITRO ACTIVATION OF CPP32 AND MCH3 BY MCH4, A NOVEL HUMAN APOPTOTIC CYSTEINE PROTEASE CONTAINING 2 FADD-LIKE DOMAINS, Proceedings of the National Academy of Sciences of the United Statesof America, 93(15), 1996, pp. 7464-7469
APOPTOTIC SUPPRESSION BY BACULOVIRUS P35 INVOLVES CLEAVAGE BY AND INHIBITION OF A VIRUS-INDUCED CED-3 ICE-LIKE PROTEASE/
Authors: BERTIN J MENDRYSA SM LACOUNT DJ GAUR S KREBS JF ARMSTRONG RC TOMASELLI KJ FRIESEN PD
Citation: J. Bertin et al., APOPTOTIC SUPPRESSION BY BACULOVIRUS P35 INVOLVES CLEAVAGE BY AND INHIBITION OF A VIRUS-INDUCED CED-3 ICE-LIKE PROTEASE/, Journal of virology, 70(9), 1996, pp. 6251-6259
THE CED-3 INTERLEUKIN 1-BETA CONVERTING ENZYME-LIKE HOMOLOG MCH6 AND THE LAMIN-CLEAVING ENZYME MCH2-ALPHA ARE SUBSTRATES FOR THE APOPTOTIC MEDIATOR CPP32/
Authors: SRINIVASULA SM FERNANDESALNEMRI T ZANGRILLI J ROBERTSON N ARMSTRONG RC WANG LJ TRAPANI JA TOMASELLI KJ LITWACK G ALNEMRI ES
Citation: Sm. Srinivasula et al., THE CED-3 INTERLEUKIN 1-BETA CONVERTING ENZYME-LIKE HOMOLOG MCH6 AND THE LAMIN-CLEAVING ENZYME MCH2-ALPHA ARE SUBSTRATES FOR THE APOPTOTIC MEDIATOR CPP32/, The Journal of biological chemistry, 271(43), 1996, pp. 27099-27106
FAS-INDUCED ACTIVATION OF THE CELL DEATH-RELATED PROTEASE CPP32 IS INHIBITED BY BCL-2 AND BY ICE FAMILY PROTEASE INHIBITORS
Authors: ARMSTRONG RC AJA T XIANG JL GAUR S KREBS JF HOANG K BAI X KORSMEYER J KARANEWSKY DS FRITZ LC TOMASELLI KJ
Citation: Rc. Armstrong et al., FAS-INDUCED ACTIVATION OF THE CELL DEATH-RELATED PROTEASE CPP32 IS INHIBITED BY BCL-2 AND BY ICE FAMILY PROTEASE INHIBITORS, The Journal of biological chemistry, 271(28), 1996, pp. 16850-16855
PEPTIDE INHIBITORS OF THE ICE PROTEASE FAMILY ARREST PROGRAMMED CELL-DEATH OF MOTONEURONS IN-VIVO AND IN-VITRO
Authors: MILLIGAN CE PREVETTE D YAGINUMA H HOMMA S CARDWELL C FRITZ LC TOMASELLI KJ OPPENHEIM RW SCHWARTZ LM
Citation: Ce. Milligan et al., PEPTIDE INHIBITORS OF THE ICE PROTEASE FAMILY ARREST PROGRAMMED CELL-DEATH OF MOTONEURONS IN-VIVO AND IN-VITRO, Neuron, 15(2), 1995, pp. 385-393
MCH3, A NOVEL HUMAN APOPTOTIC CYSTEINE PROTEASE HIGHLY RELATED TO CPP32
Authors: FERNANDESALNEMRI T TAKAHASHI A ARMSTRONG R KREBS J FRITZ L TOMASELLI KJ WANG L YU Z CROCE CM SALVESON G EARNSHAW WC LITWACK G ALNEMRI ES
Citation: T. Fernandesalnemri et al., MCH3, A NOVEL HUMAN APOPTOTIC CYSTEINE PROTEASE HIGHLY RELATED TO CPP32, Cancer research, 55(24), 1995, pp. 6045-6052
SECONDARY STRUCTURE OF AMYLOID BETA-PEPTIDE CORRELATES WITH NEUROTOXIC ACTIVITY IN-VITRO
Authors: SIMMONS LK MAY PC TOMASELLI KJ RYDEL RE FUSON KS BRIGHAM EF WRIGHT S LIEBERBURG I BECKER GW BREMS DN LI WY
Citation: Lk. Simmons et al., SECONDARY STRUCTURE OF AMYLOID BETA-PEPTIDE CORRELATES WITH NEUROTOXIC ACTIVITY IN-VITRO, Molecular pharmacology, 45(3), 1994, pp. 373-379
EXPRESSION OF BETA-1-INTEGRINS IN SENSORY NEURONS OF THE DORSAL-ROOT GANGLION AND THEIR FUNCTIONS IN NEURITE OUTGROWTH ON 2 LAMININ ISOFORMS
Authors: TOMASELLI KJ DOHERTY P EMMETT CJ DAMSKY CH WALSH FS REICHARDT LF
Citation: Kj. Tomaselli et al., EXPRESSION OF BETA-1-INTEGRINS IN SENSORY NEURONS OF THE DORSAL-ROOT GANGLION AND THEIR FUNCTIONS IN NEURITE OUTGROWTH ON 2 LAMININ ISOFORMS, The Journal of neuroscience, 13(11), 1993, pp. 4880-4888
CALCIUM-DESTABILIZING AND NEURODEGENERATIVE EFFECTS OF AGGREGATED BETA-AMYLOID PEPTIDE ARE ATTENUATED BY BASIC FGF
Authors: MATTSON MP TOMASELLI KJ RYDEL RE
Citation: Mp. Mattson et al., CALCIUM-DESTABILIZING AND NEURODEGENERATIVE EFFECTS OF AGGREGATED BETA-AMYLOID PEPTIDE ARE ATTENUATED BY BASIC FGF, Brain research, 621(1), 1993, pp. 35-49
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