Authors:
Oishi, S
Tamamura, H
Yamashita, M
Odagaki, Y
Hamanaka, N
Otaka, A
Fujii, N
Citation: S. Oishi et al., Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu, J CHEM S P1, (19), 2001, pp. 2445-2451
Authors:
Tamamura, H
Omagari, A
Hiramatsu, K
Kanamoto, T
Gotoh, K
Kanbara, K
Yamamoto, N
Nakashima, H
Otaka, A
Fujii, N
Citation: H. Tamamura et al., Synthesis and evaluation of bifunctional anti-HIV agents based on specificCXCR4 antagonists-AZT conjugation, BIO MED CH, 9(8), 2001, pp. 2179-2187
Authors:
Tamamura, H
Sugioka, M
Odagaki, Y
Omagari, A
Kan, Y
Oishi, S
Nakashima, H
Yamamoto, N
Peiper, SC
Hamanaka, N
Otaka, A
Fujii, N
Citation: H. Tamamura et al., Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity, BIOORG MED, 11(3), 2001, pp. 359-362
Authors:
Tamamura, H
Sugioka, M
Odagaki, Y
Omagari, A
Kan, Y
Oishi, S
Nakashima, H
Yamamoto, N
Peiper, SC
Hamanaka, N
Otaka, A
Fujii, N
Citation: H. Tamamura et al., Conformational study of a highly specific CXCR4 inhibitor, T140, disclosing the close proximity of its intrinsic pharmacophores associated with strong anti-HIV activity (vol 11, pg 359, 2001), BIOORG MED, 11(17), 2001, pp. 2409-2409
Authors:
Tamamura, H
Omagari, A
Hiramatsu, K
Gotoh, K
Kanamoto, T
Xu, YN
Kodama, E
Matsuoka, M
Hattori, T
Yamamoto, N
Nakashima, H
Otaka, A
Fujii, N
Citation: H. Tamamura et al., Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140, BIOORG MED, 11(14), 2001, pp. 1897-1902
Authors:
Kanbara, K
Sato, S
Tanuma, J
Tamamura, H
Gotoh, K
Yoshimori, M
Kanamoto, T
Kitano, M
Fujii, N
Nakashima, H
Citation: K. Kanbara et al., Biological and genetic characterization of a human immunodeficiency virus strain resistant to CXCR4 antagonist t134, AIDS RES H, 17(7), 2001, pp. 615-622
Authors:
Otaka, A
Watanabe, H
Yukimasa, A
Oishi, S
Tamamura, H
Fujii, N
Citation: A. Otaka et al., New access to alpha-substituted (Z)-fluoroalkene dipeptide isosteres utilizing organocopper reagents under 'reduction-oxidative alkylation (R-OA)' conditions, TETRAHEDR L, 42(32), 2001, pp. 5443-5446
Authors:
Otaka, A
Watanabe, H
Mitsuyama, E
Yukimasa, A
Tamamura, H
Fujii, N
Citation: A. Otaka et al., Synthesis of (Z)-fluoroalkene dipeptide isosteres utilizing organocopper-mediated reduction of gamma,gamma-difluoro-alpha,beta-enoates, TETRAHEDR L, 42(2), 2001, pp. 285-287
Authors:
Otaka, A
Mitsuyama, E
Watanabe, H
Tamamura, H
Fujii, N
Citation: A. Otaka et al., Development of new methodology for the synthesis of functionalized alpha-fluorophosphonates and its practical application to the preparation of phosphopeptide mimetics, CHEM COMMUN, (12), 2000, pp. 1081-1082
Authors:
Tamamura, H
Omagari, A
Oishi, S
Kanamoto, T
Yamamoto, N
Peiper, SC
Nakashima, H
Otaka, A
Fujii, N
Citation: H. Tamamura et al., Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads todevelopment of effective anti-HIV agents with very high selectivity indexes, BIOORG MED, 10(23), 2000, pp. 2633-2637
Authors:
Kitazawa, M
Tamamura, H
Nakano, S
Kigoshi, T
Uchida, K
Citation: M. Kitazawa et al., Treatment of renovascular hypertension using stent implantation in an elderly patient with NIDDM, INTERN MED, 39(6), 2000, pp. 464-467
Authors:
Kakugawa, K
Udaka, K
Nakashima, K
Inaba, K
Oka, Y
Sugiyama, H
Tamamura, H
Yamagishi, H
Citation: K. Kakugawa et al., Efficient induction of peptide-specific cytotoxic T lymphocytes by LPS-activated spleen cells, MICROB IMMU, 44(2), 2000, pp. 123-133
Authors:
Udaka, K
Wiesmuller, KH
Kienle, S
Jung, G
Tamamura, H
Yamagishi, H
Okumura, K
Walden, P
Suto, T
Kawasaki, T
Citation: K. Udaka et al., An automated prediction of MHC class I-binding peptides based on positional scanning with peptide libraries, IMMUNOGENET, 51(10), 2000, pp. 816-828
Authors:
Otaka, A
Mitsuyama, E
Kinoshita, T
Tamamura, H
Fujii, N
Citation: A. Otaka et al., Stereoselective synthesis of CF2-substituted phosphothreonine mimetics andtheir incorporation into peptides using newly developed deprotection procedures, J ORG CHEM, 65(16), 2000, pp. 4888-4899
Authors:
Tamamura, H
Bienfait, B
Nacro, K
Lewin, NE
Blumberg, PM
Marquez, VE
Citation: H. Tamamura et al., Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C, J MED CHEM, 43(17), 2000, pp. 3209-3217
Authors:
Xu, YN
Tamamura, H
Arakaki, R
Nakashima, H
Zhang, XY
Fujii, N
Uchiyama, T
Hattori, T
Citation: Yn. Xu et al., Marked increase in anti-HIV activity, as well as inhibitory activity against HIV entry mediated by CXCR4, linked to enhancement of the binding ability of tachyplesin analogs to CXCR4, AIDS RES H, 15(5), 1999, pp. 419-427
Authors:
Tamamura, H
Yamashita, M
Nakajima, Y
Sakano, K
Otaka, A
Ohno, H
Ibuka, T
Fujii, N
Citation: H. Tamamura et al., Regiospecific ring-opening reactions of beta-aziridinyl alpha,beta-enoateswith acids: application to the stereoselective synthesis of a couple of diastereoisomeric (E)-alkene dipeptide isosteres from a single beta-aziridinyl alpha,beta-enoate and to the convenient preparation of amino alcohols bearing alpha,beta-unsaturated ester groups, J CHEM S P1, (20), 1999, pp. 2983-2996
Authors:
Murakami, T
Zhang, TY
Koyanagi, Y
Tanaka, Y
Kim, J
Suzuki, Y
Minoguchi, S
Tamamura, H
Waki, M
Matsumoto, A
Fujii, N
Shida, H
Hoxie, JA
Peiper, SC
Yamamoto, N
Citation: T. Murakami et al., Inhibitory mechanism of the CXCR4 antagonist t22 against human immunodeficiency virus type 1 infection, J VIROLOGY, 73(9), 1999, pp. 7489-7496
Authors:
Arakaki, R
Tamamura, H
Premanathan, M
Kanbara, K
Ramanan, S
Mochizuki, K
Baba, M
Fujii, N
Nakashima, H
Citation: R. Arakaki et al., T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure, J VIROLOGY, 73(2), 1999, pp. 1719-1723
Authors:
Ohno, H
Ishii, K
Honda, A
Tamamura, H
Fujii, N
Takemoto, Y
Ibuka, T
Citation: H. Ohno et al., A 2,3-cis-selective synthesis of aziridines bearing a vinyl group from allyl methyl carbonates and allyl mesylates, J CHEM S P1, (22), 1998, pp. 3703-3716
Authors:
Tamamura, H
Xu, YO
Hattori, T
Zhang, XY
Arakaki, R
Kanbara, K
Omagari, A
Otaka, A
Ibuka, T
Yamamoto, N
Nakashima, H
Fujii, N
Citation: H. Tamamura et al., A low-molecular-weight inhibitor against the chemokine receptor CXCR4: A strong anti-HIV peptide T140, BIOC BIOP R, 253(3), 1998, pp. 877-882