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Results: 1-8 |
Results: 8
In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization
Authors: Yergey, JA Trimble, LA Silva, J Chauret, N Li, C Therien, M Grimm, E Nicoll-Griffith, DA
Citation: Ja. Yergey et al., In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization, DRUG META D, 29(5), 2001, pp. 638-644
Synthesis of rofecoxib, (MK 0966, Vioxx((R)) 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2
Authors: Therien, M Gauthier, JY Leblanc, Y Leger, S Perrier, H Prasit, P Wang, ZI
Citation: M. Therien et al., Synthesis of rofecoxib, (MK 0966, Vioxx((R)) 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone), a selective and orally active inhibitor of cyclooxygenase-2, SYNTHESIS-S, (12), 2001, pp. 1778-1779
Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM))
Authors: Nicoll-Griffith, DA Yergey, JA Trimble, LA Silva, JM Li, C Chauret, N Gauthier, JY Grimm, E Leger, S Roy, P Therien, M Wang, ZY Prasit, P Zamboni, R Young, RN Brideau, C Chan, CC Mancini, J Riendeau, D
Citation: Da. Nicoll-griffith et al., Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM)), BIOORG MED, 10(23), 2000, pp. 2683-2686
A new structural variation on the methanesulfonylphenyl class of selectivecyclooxygenase-2 inhibitors
Authors: Li, CS Black, WC Brideau, C Chan, CC Charleson, S Cromlish, WA Claveau, D Gauthier, JY Gordon, R Greig, G Grimm, E Guay, J Lau, CK Riendeau, D Therien, M Visco, DM Wong, E Xu, LJ Prasit, P
Citation: Cs. Li et al., A new structural variation on the methanesulfonylphenyl class of selectivecyclooxygenase-2 inhibitors, BIOORG MED, 9(22), 1999, pp. 3181-3186
Synthesis and biological evaluation of 3-heteroarizoxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors
Authors: Lau, CK Brideau, C Chan, CC Charleson, S Cromlish, WA Ethier, D Gauthier, JY Gordon, R Guay, J Kargman, S Li, CS Prasit, P Riendeau, D Therien, M Visco, DM Xu, LJ
Citation: Ck. Lau et al., Synthesis and biological evaluation of 3-heteroarizoxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors, BIOORG MED, 9(22), 1999, pp. 3187-3192
Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors
Authors: Frenette, R Hutchinson, JH Leger, S Therien, M Brideau, C Chan, CC Charleson, S Ethier, D Guay, J Jones, TR McAuliffe, M Piechuta, H Riendeau, D Tagari, P Girard, Y
Citation: R. Frenette et al., Substituted indoles as potent and orally active 5-lipoxygenase activating protein (FLAP) inhibitors, BIOORG MED, 9(16), 1999, pp. 2391-2396
The discovery of rofecoxib, [MK 966, Vioxx (R), 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor
Authors: Prasit, P Wang, Z Brideau, C Chan, CC Charleson, S Cromlish, W Ethier, D Evans, JF Ford-Hutchinson, AW Gauthier, JY Gordon, R Guay, J Gresser, M Kargman, S Kennedy, B Leblanc, Y Leger, S Mancini, J O'Neill, GP Ouellet, M Percival, MD Perrier, H Riendeau, D Rodger, I Tagari, P Therien, M Vickers, P Wong, E Xu, LJ Young, RN Zamboni, R Boyce, S Rupniak, N Forrest, N Visco, D Patrick, D
Citation: P. Prasit et al., The discovery of rofecoxib, [MK 966, Vioxx (R), 4-(4 '-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2 inhibitor, BIOORG MED, 9(13), 1999, pp. 1773-1778
Rofecoxib [Vioxx, MK-0966; 4-(4 '-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
Authors: Chan, CC Boyce, S Brideau, C Charleson, S Cromlish, W Ethier, D Evans, J Ford-Hutchinson, AW Forrest, MJ Gauthier, JY Gordon, R Gresser, M Guay, J Kargman, S Kennedy, B Leblanc, Y Leger, S Mancini, J O'Neill, GP Ouellet, M Patrick, D Percival, MD Perrier, H Prasit, P Rodger, I Tagari, P Therien, M Vickers, P Visco, D Wang, Z Webb, J Wong, E Xu, LJ Young, RN Zamboni, R Riendeau, D
Citation: Cc. Chan et al., Rofecoxib [Vioxx, MK-0966; 4-(4 '-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles, J PHARM EXP, 290(2), 1999, pp. 551-560
Risultati: 1-8 |