Authors:
Chauret, N
Yergey, JA
Brideau, C
Friesen, RW
Mancini, J
Riendeau, D
Silva, J
Styhler, A
Trimble, LA
Nicoll-Griffith, DA
Citation: N. Chauret et al., In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663), BIOORG MED, 11(8), 2001, pp. 1059-1062
Authors:
Yergey, JA
Trimble, LA
Silva, J
Chauret, N
Li, C
Therien, M
Grimm, E
Nicoll-Griffith, DA
Citation: Ja. Yergey et al., In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization, DRUG META D, 29(5), 2001, pp. 638-644
Authors:
Li, C
Chauret, N
Trimble, LA
Nicoll-Griffith, DA
Silva, JM
Macdonald, D
Perrier, H
Yergey, JA
Parton, T
Alexander, RP
Warrellow, GJ
Citation: C. Li et al., Investigation of the in vitro metabolism profile of a phosphodiesterase-IVinhibitor, CDP-840: Leading to structural optimization, DRUG META D, 29(3), 2001, pp. 232-241
Authors:
Nicoll-Griffith, DA
Yergey, JA
Trimble, LA
Silva, JM
Li, C
Chauret, N
Gauthier, JY
Grimm, E
Leger, S
Roy, P
Therien, M
Wang, ZY
Prasit, P
Zamboni, R
Young, RN
Brideau, C
Chan, CC
Mancini, J
Riendeau, D
Citation: Da. Nicoll-griffith et al., Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM)), BIOORG MED, 10(23), 2000, pp. 2683-2686
Authors:
Trimble, LA
Shankar, P
Patterson, M
Daily, JP
Lieberman, J
Citation: La. Trimble et al., Human immunodeficiency virus-specific circulating CD8 T lymphocytes have down-modulated CD3 zeta and CD28, key signaling molecules for T-cell activation, J VIROLOGY, 74(16), 2000, pp. 7320-7330
Authors:
Lieberman, J
Trimble, LA
Friedman, RS
Lisziewicz, J
Lori, F
Shankar, P
Jessen, H
Citation: J. Lieberman et al., Expansion of CD57 and CD62L(-)CD45RA(+) CD8 T lymphocytes correlates with reduced viral plasma RNA after primary HIV infection, AIDS, 13(8), 1999, pp. 891-899
Citation: La. Trimble et al., Clonal expansion of antigen-specific CD8+cytotoxic T lymphocytes is regulated by late exposure to serum to prevent apoptosis, J IMMUNOL M, 225(1-2), 1999, pp. 39-52