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Results: 1-25 |
Results: 25
The first stereospecific synthesis of L-tetrahydrodipicolinic acid; a key intermediate of diaminopimelate metabolism
Authors: Caplan, JF Sutherland, A Vederas, JC
Citation: Jf. Caplan et al., The first stereospecific synthesis of L-tetrahydrodipicolinic acid; a key intermediate of diaminopimelate metabolism, J CHEM S P1, (18), 2001, pp. 2217-2220
Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus
Authors: Auclair, K Kennedy, J Hutchinson, CR Vederas, JC
Citation: K. Auclair et al., Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus, BIOORG MED, 11(12), 2001, pp. 1527-1531
Vinylogous amide analogues of diaminopimelic acid (DAP) as inhibitors of enzymes involved in bacterial lysine biosynthesis
Authors: Caplan, JF Zheng, RJ Blanchard, JS Vederas, JC
Citation: Jf. Caplan et al., Vinylogous amide analogues of diaminopimelic acid (DAP) as inhibitors of enzymes involved in bacterial lysine biosynthesis, ORG LETT, 2(24), 2000, pp. 3857-3860
Characterization of the genetic locus responsible for production and immunity of carnobacteriocin A: the immunity gene confers cross-protection to enterocin B
Authors: Franz, CMAP van Belkum, MJ Worobo, RW Vederas, JC Stiles, ME
Citation: Cmap. Franz et al., Characterization of the genetic locus responsible for production and immunity of carnobacteriocin A: the immunity gene confers cross-protection to enterocin B, MICROBIO-UK, 146, 2000, pp. 621-631
Bacterial diaminopimelate metabolism as a target for antibiotic design
Authors: Cox, RJ Sutherland, A Vederas, JC
Citation: Rj. Cox et al., Bacterial diaminopimelate metabolism as a target for antibiotic design, BIO MED CH, 8(5), 2000, pp. 843-871
The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate
Authors: Cirilli, M Scapin, G Sutherland, A Vederas, JC Blanchard, JS
Citation: M. Cirilli et al., The three-dimensional structure of the ternary complex of Corynebacterium glutamicum diaminopimelate dehydrogenase-NADPH-L-2-amino-6-methylene-pimelate, PROTEIN SCI, 9(10), 2000, pp. 2034-2037
Analogues of bacteriocins: Antimicrobial specificity and interactions of leucocin A with its enantiomer, carnobacteriocin B2, and truncated derivatives
Authors: Yan, LZ Gibbs, AC Stiles, ME Wishart, DS Vederas, JC
Citation: Lz. Yan et al., Analogues of bacteriocins: Antimicrobial specificity and interactions of leucocin A with its enantiomer, carnobacteriocin B2, and truncated derivatives, J MED CHEM, 43(24), 2000, pp. 4579-4581
Amidation of salicyluric acid and gentisuric acid: A possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin
Authors: DeBlassio, JL deLong, MA Glufke, U Kulathila, R Merkler, KA Vederas, JC Merkler, DJ
Citation: Jl. Deblassio et al., Amidation of salicyluric acid and gentisuric acid: A possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin, ARCH BIOCH, 383(1), 2000, pp. 46-55
The enzymatic formation of novel bile acid primary amides
Authors: King, L Barnes, S Glufke, U Henz, ME Kirk, M Merkler, KA Vederas, JC Wilcox, BJ Merkler, DJ
Citation: L. King et al., The enzymatic formation of novel bile acid primary amides, ARCH BIOCH, 374(2), 2000, pp. 107-117
Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue
Authors: Auclair, K Sutherland, A Kennedy, J Witter, DJ Van den Heever, JP Hutchinson, CR Vederas, JC
Citation: K. Auclair et al., Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue, J AM CHEM S, 122(46), 2000, pp. 11519-11520
Identification of active site cysteine residues that function as general bases: Diaminopimelate epimerase
Authors: Koo, CW Sutherland, A Vederas, JC Blanchard, JS
Citation: Cw. Koo et al., Identification of active site cysteine residues that function as general bases: Diaminopimelate epimerase, J AM CHEM S, 122(25), 2000, pp. 6122-6123
beta-lactones as a new class of cysteine proteinase inhibitors: Inhibitionof hepatitis a virus 3C proteinase by N-Cbz-serine beta-lactone
Authors: Lall, MS Karvellas, C Vederas, JC
Citation: Ms. Lall et al., beta-lactones as a new class of cysteine proteinase inhibitors: Inhibitionof hepatitis a virus 3C proteinase by N-Cbz-serine beta-lactone, ORG LETT, 1(5), 1999, pp. 803-806
Unsaturated alpha-aminopimelic acids as potent inhibitors of meso-diaminopimelic acid (DAP) D-dehydrogenase
Authors: Sutherland, A Caplan, JF Vederas, JC
Citation: A. Sutherland et al., Unsaturated alpha-aminopimelic acids as potent inhibitors of meso-diaminopimelic acid (DAP) D-dehydrogenase, CHEM COMMUN, (6), 1999, pp. 555-556
The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid
Authors: Sutherland, A Vederas, JC
Citation: A. Sutherland et Jc. Vederas, The first isolation of an alkoxy-N,N-dialkylaminodifluorosulfane from the reaction of an alcohol and DAST: an efficient synthesis of (2S,3R,6S)-3-fluoro-2,6-diaminopimelic acid, CHEM COMMUN, (17), 1999, pp. 1739-1740
Synthesis and testing of azaglutamine derivatives as inhibitors of hepatitis A virus (HAV) 3C proteinase
Authors: Huang, YT Malcolm, BA Vederas, JC
Citation: Yt. Huang et al., Synthesis and testing of azaglutamine derivatives as inhibitors of hepatitis A virus (HAV) 3C proteinase, BIO MED CH, 7(4), 1999, pp. 607-619
Atypical genetic locus associated with constitutive production of enterocin B by Enterococcus faecium BFE 900
Authors: Franz, CMAP Worobo, RW Quadri, LEN Schillinger, U Holzapfel, WH Vederas, JC Stiles, ME
Citation: Cmap. Franz et al., Atypical genetic locus associated with constitutive production of enterocin B by Enterococcus faecium BFE 900, APPL ENVIR, 65(5), 1999, pp. 2170-2178
Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis a virus (HAV) and implications for the polyprotein processing in HAV
Authors: Bergmann, EM Cherney, MM Mckendrick, J Frormann, S Luo, C Malcolm, BA Vederas, JC James, MNG
Citation: Em. Bergmann et al., Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis a virus (HAV) and implications for the polyprotein processing in HAV, VIROLOGY, 265(1), 1999, pp. 153-163
Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis
Authors: Kennedy, J Auclair, K Kendrew, SG Park, C Vederas, JC Hutchinson, CR
Citation: J. Kennedy et al., Modulation of polyketide synthase activity by accessory proteins during lovastatin biosynthesis, SCIENCE, 284(5418), 1999, pp. 1368-1372
Azodicarboxamides: A new class of cysteine proteinase inhibitor for hepatitis A virus and human rhinovirus 3C enzymes
Authors: Hill, RD Vederas, JC
Citation: Rd. Hill et Jc. Vederas, Azodicarboxamides: A new class of cysteine proteinase inhibitor for hepatitis A virus and human rhinovirus 3C enzymes, J ORG CHEM, 64(26), 1999, pp. 9538-9546
Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin
Authors: Zheng, GL Yan, LZ Vederas, JC Zuber, P
Citation: Gl. Zheng et al., Genes of the sbo-alb locus of Bacillus subtilis are required for production of the antilisterial bacteriocin subtilosin, J BACT, 181(23), 1999, pp. 7346-7355
Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria
Authors: Wang, YJ Henz, ME Gallagher, NLF Chai, SY Gibbs, AC Yan, LZ Stiles, ME Wishart, DS Vederas, JC
Citation: Yj. Wang et al., Solution structure of carnobacteriocin B2 and implications for structure-activity relationships among type IIa bacteriocins from lactic acid bacteria, BIOCHEM, 38(47), 1999, pp. 15438-15447
N-acylglycine amidation: Implications for the biosynthesis of fatty acid primary amides
Authors: Wilcox, BJ Ritenour-Rodgers, KJ Asser, AS Baumgart, LE Baumgart, MA Boger, DL DeBlassio, JL deLong, MA Glufke, U Henz, ME King, L Merkler, KA Patterson, JE Robleski, JJ Vederas, JC Merkler, DJ
Citation: Bj. Wilcox et al., N-acylglycine amidation: Implications for the biosynthesis of fatty acid primary amides, BIOCHEM, 38(11), 1999, pp. 3235-3245
Formation of nicotinamide from nicotinuric acid by peptidylglycine alpha-amidating monooxygenase (PAM): A possible alternative route from nicotinic acid (niacin) to NADP in mammals
Authors: Merkler, DJ Glufke, U Ritenour-Rodgers, KJ Baumgart, LE DeBlassio, JL Merkler, KA Vederas, JC
Citation: Dj. Merkler et al., Formation of nicotinamide from nicotinuric acid by peptidylglycine alpha-amidating monooxygenase (PAM): A possible alternative route from nicotinic acid (niacin) to NADP in mammals, J AM CHEM S, 121(20), 1999, pp. 4904-4905
Genetic characterization and heterologous expression of brochocin-C, an antibotulinal, two-peptide bacteriocin produced by Brochothrix campestris ATCC 43754
Authors: McCormick, JK Poon, A Sailer, M Gao, Y Roy, KL McMullen, LM Vederas, JC Stiles, ME Van Belkum, MJ
Citation: Jk. Mccormick et al., Genetic characterization and heterologous expression of brochocin-C, an antibotulinal, two-peptide bacteriocin produced by Brochothrix campestris ATCC 43754, APPL ENVIR, 64(12), 1998, pp. 4757-4766
Biosynthetic incorporation of advanced precursors into dehydrocurvularin, a polyketide phytotoxin from Alternaria cinerariae
Authors: Liu, YQ Li, Z Vederas, JC
Citation: Yq. Liu et al., Biosynthetic incorporation of advanced precursors into dehydrocurvularin, a polyketide phytotoxin from Alternaria cinerariae, TETRAHEDRON, 54(52), 1998, pp. 15937-15958
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