Authors:
Wasan, KM
Peteherych, KD
Najafi, S
Zamfir, C
Pritchard, PH
Citation: Km. Wasan et al., Assessing the plasma pharmacokinetics, tissue distribution, excretion and effects on cholesterol pharmacokinetics of a novel hydrophilic compound, FM-VP4, following administration to rats., J PHARM P S, 4(3), 2001, pp. 207-216
Authors:
Wasan, KM
Najafi, S
Wong, J
Kwong, M
Pritchard, PH
Citation: Km. Wasan et al., Assessing plasma lipid levels, body weight, and hepatic and renal toxicityfollowing chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils., J PHARM P S, 4(3), 2001, pp. 228-234
Authors:
Wasan, KM
Ramaswamy, M
Holtorf, L
Jayaraj, AA
Hauss, DJ
Citation: Km. Wasan et al., Rat and rabbit plasma distribution of free and chylomicron-associated BIRT377, a novel small molecule antagonist of LFA-1-mediated cell adhesion, PHARM RES, 18(4), 2001, pp. 510-519
Citation: M. Ramaswamy et Km. Wasan, Differences in the method by which plasma is separated from whole blood influences amphotericin B plasma recovery and distribution following amphotericin B lipid complex incubation within whole blood, DRUG DEV IN, 27(8), 2001, pp. 871-875
Citation: Km. Wasan, Formulation and physiological and biopharmaceutical issues in the development of oral lipid-based drug delivery systems, DRUG DEV IN, 27(4), 2001, pp. 267-276
Authors:
Kwong, EH
Ramaswamy, M
Bauer, EA
Hartsel, SC
Wasan, KM
Citation: Eh. Kwong et al., Heat treatment of amphotericin B modifies its serum pharmacokinetics, tissue distribution, and renal toxicity following administration of a single intravenous dose to rabbits, ANTIM AG CH, 45(7), 2001, pp. 2060-2063
Authors:
Ramaswamy, M
Peteherych, KD
Kennedy, AL
Wasan, KM
Citation: M. Ramaswamy et al., Amphotericin B lipid complex or amphotericin B multiple-dose administration to rabbits with elevated plasma cholesterol levels: Pharmacokinetics in plasma and blood, plasma lipoprotein levels, distribution in tissues, and renal toxicities, ANTIM AG CH, 45(4), 2001, pp. 1184-1191
Citation: M. Kwong et al., Cyclosporine A transfer between high- and low-density lipoproteins: Independent from lipid transfer protein I-facilitated transfer of lipoprotein-coated phospholipids because of high affinity of cyclosporine A for the protein component of lipoproteins, J PHARM SCI, 90(9), 2001, pp. 1308-1317
Citation: Kd. Peteherych et Km. Wasan, Effects of lipoproteins on cyclosporine A toxicity and uptake in LLC-PK1 pig kidney cells, J PHARM SCI, 90(9), 2001, pp. 1395-1406
Authors:
Hartsel, SC
Baas, B
Bauer, E
Foree, LT
Kindt, K
Preis, H
Scott, A
Kwong, EH
Ramaswamy, M
Wasan, KM
Citation: Sc. Hartsel et al., Heat-induced superaggregation of Amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha, J PHARM SCI, 90(2), 2001, pp. 124-133
Authors:
Wasan, KM
Najafi, S
Peteherych, KD
Pritchard, PH
Citation: Km. Wasan et al., Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils, J PHARM SCI, 90(11), 2001, pp. 1795-1799
Authors:
Wasan, KM
Holtorf, L
Subramanian, R
Cassidy, SM
Pritchard, PH
Stewart, DI
Novak, E
Citation: Km. Wasan et al., Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats, J PHARM SCI, 90(1), 2001, pp. 23-28
Authors:
Brocks, DR
Ramaswamy, M
MacInnes, AI
Wasan, KM
Citation: Dr. Brocks et al., The stereoselective distribution of halofantrine enantiomers within human,dog, and rat plasma lipoproteins, PHARM RES, 17(4), 2000, pp. 427-431
Authors:
Rose, JR
Mullarkey, MA
Christ, WJ
Hawkins, LD
Lynn, M
Kishi, Y
Wasan, KM
Peteherych, K
Rossignol, DP
Citation: Jr. Rose et al., Consequences of interaction of a lipophilic endotoxin antagonist with plasma lipoproteins, ANTIM AG CH, 44(3), 2000, pp. 504-510
Authors:
Wasan, KM
Subramanian, R
Chou, JWL
Ramaswamy, M
Pritchard, PH
Citation: Km. Wasan et al., Cyclosporine transfer from low- and high-density lipoproteins is partiallyinfluenced by lipid transfer protein I triglyceride transfer activity, PHARM RES, 16(7), 1999, pp. 1067-1073
Authors:
Wasan, KM
Cassidy, SM
Ramaswamy, M
Kennedy, A
Strobel, FW
Ng, SP
Lee, TY
Citation: Km. Wasan et al., A comparison of step-gradient and sequential density ultracentrifugation and the use of lipoprotein deficient plasma controls in determining the plasma lipoprotein distribution of lipid-associated nystatin and cyclosporine, PHARM RES, 16(1), 1999, pp. 165-169
Authors:
Ramaswamy, M
Wallace, TL
Cossum, PA
Wasan, KM
Citation: M. Ramaswamy et al., Species differences in the proportion of plasma lipoprotein lipid carried by high-density lipoproteins influence the distribution of free and liposomal nystatin in human, dog, and rat plasma, ANTIM AG CH, 43(6), 1999, pp. 1424-1428
Authors:
Wasan, KM
Strobel, FW
Parrott, SC
Lynn, M
Christ, WJ
Hawkins, LD
Rossignol, DP
Citation: Km. Wasan et al., Lipoprotein distribution of a novel endotoxin antagonist, E5531, in plasmafrom human subjects with various lipid levels, ANTIM AG CH, 43(10), 1999, pp. 2562-2564
Authors:
McIntosh, MP
Porter, CJH
Wasan, KM
Ramaswamy, M
Charman, WN
Citation: Mp. Mcintosh et al., Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of coreapolar lipoprotein lipid, J PHARM SCI, 88(3), 1999, pp. 378-384
Authors:
Wasan, KM
Ramaswamy, M
McIntosh, MP
Porter, CJH
Charman, WN
Citation: Km. Wasan et al., Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic humanplasmas, J PHARM SCI, 88(2), 1999, pp. 185-190
Citation: Al. Kennedy et Km. Wasan, Preferential distribution of amphotericin B lipid complex into human HDL3 is a consequence of high density lipoprotein coat lipid content, J PHARM SCI, 88(11), 1999, pp. 1149-1155