AAAAAA

   
Results: 1-25 | 26-50 | 51-52
Results: 1-25/52
LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: Conformational tuning and high-affinity recognition of DNA/RNA targets
Authors: Wengel, J Petersen, M Nielsen, KE Jensen, GA Hakansson, AE Kumar, R Sorensen, MD Rajwanshi, VK Bryld, T Jacobsen, JP
Citation: J. Wengel et al., LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: Conformational tuning and high-affinity recognition of DNA/RNA targets, NUCLEOS NUC, 20(4-7), 2001, pp. 389-396
Oligonucleotide analogue interference with the HIV-1 Tat protein-TAR RNA interaction
Authors: Arzumanov, A Walsh, AP Liu, XH Rajwanshi, VK Wengel, J Gait, MJ
Citation: A. Arzumanov et al., Oligonucleotide analogue interference with the HIV-1 Tat protein-TAR RNA interaction, NUCLEOS NUC, 20(4-7), 2001, pp. 471-480
A comparison of the solution structures of an LNA : DNA duplex and the unmodified DNA : DNA duplex
Authors: Jensen, GA Singh, SK Kumar, R Wengel, J Jacobsen, JP
Citation: Ga. Jensen et al., A comparison of the solution structures of an LNA : DNA duplex and the unmodified DNA : DNA duplex, J CHEM S P2, (7), 2001, pp. 1224-1232
Synthesis and evaluation of anti-HIV activity of 3-azido-4-(hydroxymethyl)tetrahydrofuran derivatives containing 2-(thymin-1-yl)methyl, 2-(cytosin-1-yl)methyl or 2-(adenin-9-yl)methyl substituents - a new series of AZT analogues
Authors: Olsen, AG Nielsen, C Wengel, J
Citation: Ag. Olsen et al., Synthesis and evaluation of anti-HIV activity of 3-azido-4-(hydroxymethyl)tetrahydrofuran derivatives containing 2-(thymin-1-yl)methyl, 2-(cytosin-1-yl)methyl or 2-(adenin-9-yl)methyl substituents - a new series of AZT analogues, J CHEM S P1, (8), 2001, pp. 900-904
X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer
Authors: Egli, M Minasov, G Teplova, M Kumar, R Wengel, J
Citation: M. Egli et al., X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer, CHEM COMMUN, (7), 2001, pp. 651-652
Universal hybridization using LNA (locked nucleic acid) containing a novelpyrene LNA nucleotide monomer
Authors: Babu, BR Wengel, J
Citation: Br. Babu et J. Wengel, Universal hybridization using LNA (locked nucleic acid) containing a novelpyrene LNA nucleotide monomer, CHEM COMMUN, (20), 2001, pp. 2114-2115
Antisense molecules and furanose conformations - is it really that simple?
Authors: Kvaerno, L Wengel, J
Citation: L. Kvaerno et J. Wengel, Antisense molecules and furanose conformations - is it really that simple?, CHEM COMMUN, (16), 2001, pp. 1419-1424
Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: Protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom
Authors: Raj, HG Kohli, E Goswami, R Goel, S Rastogi, RC Jain, SC Wengel, J Olsen, CE Parmar, VS
Citation: Hg. Raj et al., Mechanism of biochemical action of substituted benzopyran-2-ones. Part 8: Acetoxycoumarin: Protein transacetylase specificity for aromatic nuclear acetoxy groups in proximity to the oxygen heteroatom, BIO MED CH, 9(5), 2001, pp. 1085-1089
Stereocontrolled synthesis of LNA dinucleoside phosphorothioate by the oxathiaphospholane approach
Authors: Karwowski, B Okruszek, A Wengel, J Stec, WJ
Citation: B. Karwowski et al., Stereocontrolled synthesis of LNA dinucleoside phosphorothioate by the oxathiaphospholane approach, BIOORG MED, 11(8), 2001, pp. 1001-1003
The adenine derivative of alpha-L-LNA (alpha-L-ribo configured locked nucleic acid): Synthesis and high-affinity hybridization towards DNA, RNA, LNA and alpha-L-LNA complementary sequences
Authors: Hakansson, AE Wengel, J
Citation: Ae. Hakansson et J. Wengel, The adenine derivative of alpha-L-LNA (alpha-L-ribo configured locked nucleic acid): Synthesis and high-affinity hybridization towards DNA, RNA, LNA and alpha-L-LNA complementary sequences, BIOORG MED, 11(7), 2001, pp. 935-938
Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as tripler forming branch (vol 10, pg 1853, 2000)
Authors: Sorensen, MD Meldgaard, M Raunkjaer, M Rajwanshi, VK Wengel, J
Citation: Md. Sorensen et al., Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as tripler forming branch (vol 10, pg 1853, 2000), BIOORG MED, 11(5), 2001, pp. 751-751
Stopped-flow kinetics of lacked nucleic acid (LNA)-oligonucleotide duplex formation: studies of LNA-DNA and DNA-DNA interactions
Authors: Christensen, U Jacobsen, N Rajwanshi, VK Wengel, J Koch, T
Citation: U. Christensen et al., Stopped-flow kinetics of lacked nucleic acid (LNA)-oligonucleotide duplex formation: studies of LNA-DNA and DNA-DNA interactions, BIOCHEM J, 354, 2001, pp. 481-484
Parallel synthesis of a small library of novel aminoglycoside analogs based on 2-amino-2-deoxy-D-glucose and D-ribose scaffolds
Authors: Rosenbohm, C Vanden Berghe, D Vlietinck, A Wengel, J
Citation: C. Rosenbohm et al., Parallel synthesis of a small library of novel aminoglycoside analogs based on 2-amino-2-deoxy-D-glucose and D-ribose scaffolds, TETRAHEDRON, 57(29), 2001, pp. 6277-6287
Novel bicyclic nucleoside analogue (1S,5S,6S)-6-hydroxy-5-hydroxymethyl-1-(uracil-1-yl)-3,8-dioxabicyclo[3.2.1]octane: Synthesis and incorporation into oligodeoxynucleotides
Authors: Kvaerno, L Wengel, J
Citation: L. Kvaerno et J. Wengel, Novel bicyclic nucleoside analogue (1S,5S,6S)-6-hydroxy-5-hydroxymethyl-1-(uracil-1-yl)-3,8-dioxabicyclo[3.2.1]octane: Synthesis and incorporation into oligodeoxynucleotides, J ORG CHEM, 66(16), 2001, pp. 5498-5503
Synthesis of a novel bicyclic nucleoside restricted to an S-type conformation and initial evaluation of its hybridization properties when incorporated into oligodeoxynucleotides
Authors: Kvaerno, L Wightman, RH Wengel, J
Citation: L. Kvaerno et al., Synthesis of a novel bicyclic nucleoside restricted to an S-type conformation and initial evaluation of its hybridization properties when incorporated into oligodeoxynucleotides, J ORG CHEM, 66(15), 2001, pp. 5106-5112
Inhibition of HIV-1 Tat-dependent trans activation by steric block chimeric 2 '-O-methyl/LNA oligoribonucleotides
Authors: Arzumanov, A Walsh, AP Rajwanshi, VK Kumar, R Wengel, J Gait, MJ
Citation: A. Arzumanov et al., Inhibition of HIV-1 Tat-dependent trans activation by steric block chimeric 2 '-O-methyl/LNA oligoribonucleotides, BIOCHEM, 40(48), 2001, pp. 14645-14654
alpha-L-LNA (alpha-i-ribo configured locked nucleic acid) recognition of RNA. A study by NMR spectroscopy and molecular dynamics simulations
Authors: Petersen, M Hakansson, AE Wengel, J Jacobsen, JP
Citation: M. Petersen et al., alpha-L-LNA (alpha-i-ribo configured locked nucleic acid) recognition of RNA. A study by NMR spectroscopy and molecular dynamics simulations, J AM CHEM S, 123(30), 2001, pp. 7431-7432
LNA (locked nucleic acid)
Authors: Wengel, J
Citation: J. Wengel, LNA (locked nucleic acid), ANTISENSE DRUG TECHNOLOGY: PRINCIPLES, STRATEGIES, AND APPLICATIONS, 2001, pp. 339-357
Bicyclic nucleosides and conformational restriction of oligonucleotides
Authors: Meldgaard, M Wengel, J
Citation: M. Meldgaard et J. Wengel, Bicyclic nucleosides and conformational restriction of oligonucleotides, J CHEM S P1, (21), 2000, pp. 3539-3554
Synthesis and evaluation of anti-HIV-1 activity of 3 '-azido-3 '-deoxy-2 '-O,4 '-C-methylene-linked bicyclic thymine nucleosides
Authors: Olsen, AG Rajwanshi, VK Nielsen, C Wengel, J
Citation: Ag. Olsen et al., Synthesis and evaluation of anti-HIV-1 activity of 3 '-azido-3 '-deoxy-2 '-O,4 '-C-methylene-linked bicyclic thymine nucleosides, J CHEM S P1, (21), 2000, pp. 3610-3614
The eight stereoisomers of LNA (Locked nucleic acid): A remarkable family of strong RNA binding molecules
Authors: Rajwanshi, VK Hakansson, AE Sorensen, MD Pitsch, S Singh, SK Kumar, R Nielsen, P Wengel, J
Citation: Vk. Rajwanshi et al., The eight stereoisomers of LNA (Locked nucleic acid): A remarkable family of strong RNA binding molecules, ANGEW CHEM, 39(9), 2000, pp. 1656
Solution structure of an LNA hybridized to DNA: NMR study of the d(CT(L)GCT(L)T(L)CT(L)GC): d(GCAGAAGCAG) duplex containing four locked nucleotides
Authors: Nielsen, KE Singh, SK Wengel, J Jacobsen, JP
Citation: Ke. Nielsen et al., Solution structure of an LNA hybridized to DNA: NMR study of the d(CT(L)GCT(L)T(L)CT(L)GC): d(GCAGAAGCAG) duplex containing four locked nucleotides, BIOCONJ CHE, 11(2), 2000, pp. 228-238
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 7: Assay and characterization of 7,8-diacetoxy-4-methylcoumarin: Protein transacetylase from rat liver microsomes based on the irreversible inhibition of cytosolic glutathione S-transferase
Authors: Raj, HG Parmar, VS Jain, SC Kohli, E Ahmad, N Goel, S Tyagi, YK Sharma, SK Wengel, J Olsen, CE
Citation: Hg. Raj et al., Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 7: Assay and characterization of 7,8-diacetoxy-4-methylcoumarin: Protein transacetylase from rat liver microsomes based on the irreversible inhibition of cytosolic glutathione S-transferase, BIO MED CH, 8(7), 2000, pp. 1707-1712
Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 6: Hydrolysis of 7,8-diacetoxy-4-methylcoumarin by a novel deacetylasein rat liver microsomes - a simple method for assay and characterisation
Authors: Raj, HRG Parmar, VS Jain, SC Goel, S Tyagi, YK Sharma, SK Olsen, CE Wengel, J
Citation: Hrg. Raj et al., Mechanism of biochemical action of substituted 4-methylbenzopyran-2-ones. Part 6: Hydrolysis of 7,8-diacetoxy-4-methylcoumarin by a novel deacetylasein rat liver microsomes - a simple method for assay and characterisation, BIO MED CH, 8(1), 2000, pp. 233-237
Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as triples forming branch
Authors: Sorensen, MD Meldgaard, M Rajwanshi, VK Wengel, J
Citation: Md. Sorensen et al., Branched oligonucleotides containing bicyclic nucleotides as branching points and DNA or LNA as triples forming branch, BIOORG MED, 10(16), 2000, pp. 1853-1856
Risultati: 1-25 | 26-50 | 51-52