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Results: 1-16 |
Results: 16
Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function
Authors: Higgins, GA Grottick, AJ Ballard, TM Richards, JG Messer, J Takeshima, H Pauly-Evers, M Jenck, F Adam, G Wichmann, J
Citation: Ga. Higgins et al., Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function, NEUROPHARM, 41(1), 2001, pp. 97-107
Effects of Ro 64-6198 it nociceptin/orphanin FQ-sensitive isolated tissues
Authors: Rizzi, D Bigoni, R Rizzi, A Jenck, F Wichmann, J Guerrini, R Regoli, D Calo, G
Citation: D. Rizzi et al., Effects of Ro 64-6198 it nociceptin/orphanin FQ-sensitive isolated tissues, N-S ARCH PH, 363(5), 2001, pp. 551-555
Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site
Authors: Knoflach, F Mutel, V Kew, JNC Malherbe, P Vieira, E Wichmann, J Kemp, JA
Citation: F. Knoflach et al., Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site, P NAS US, 98(23), 2001, pp. 13402-13407
Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: Rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo
Authors: Dautzenberg, FM Wichmann, J Higelin, J Py-Lang, G Kratzeisen, C Malherbe, P Kilpatrick, GJ Jenck, F
Citation: Fm. Dautzenberg et al., Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: Rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo, J PHARM EXP, 298(2), 2001, pp. 812-819
ORL1 receptor ligands: Structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones
Authors: Rover, S Wichmann, J Jenck, F Adam, G Cesura, AM
Citation: S. Rover et al., ORL1 receptor ligands: Structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones, BIOORG MED, 10(8), 2000, pp. 831-834
Synthesis of (2S,2 ' R,3 ' R)-2-(1 '-[H-3],2 ',3 '-dicarboxylcyclopropyl)-glycine ([H-3]-DCG-IV)
Authors: Wichmann, J Huguenin, P Adam, G
Citation: J. Wichmann et al., Synthesis of (2S,2 ' R,3 ' R)-2-(1 '-[H-3],2 ',3 '-dicarboxylcyclopropyl)-glycine ([H-3]-DCG-IV), J LABEL C R, 43(1), 2000, pp. 1-10
Synthesis of (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties
Authors: Wichmann, J Adam, G Rover, S Hennig, M Scalone, M Cesura, AM Dautzenberg, FM Jenck, F
Citation: J. Wichmann et al., Synthesis of (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties, EUR J MED C, 35(9), 2000, pp. 839-851
Characterization of [H-3]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using Semliki Forest virus vectors
Authors: Schweitzer, C Kratzeisen, C Adam, G Lundstrom, K Malherbe, P Ohresser, S Stadler, H Wichmann, J Woltering, T Mutel, V
Citation: C. Schweitzer et al., Characterization of [H-3]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using Semliki Forest virus vectors, NEUROPHARM, 39(10), 2000, pp. 1700-1706
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat
Authors: Jenck, F Wichmann, J Dautzenberg, FM Moreau, JL Ouagazzal, AM Martin, JR Lundstrom, K Cesura, AM Poli, SM Roever, S Kolczewski, S Adam, G Kilpatrick, G
Citation: F. Jenck et al., A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: Anxiolytic profile in the rat, P NAS US, 97(9), 2000, pp. 4938-4943
High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor
Authors: Rover, S Adam, G Cesura, AM Galley, G Jenck, F Monsma, FJ Wichmann, J Dautzenberg, FM
Citation: S. Rover et al., High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor, J MED CHEM, 43(7), 2000, pp. 1329-1338
Structure-activity relationships of substituted 2,3,4,4a,5,10b-hexahydro-benz[h]isoquinoline-6(1H)-ones as 5-HT2C receptor antagonists
Authors: Stadler, H Wichmann, J Sleight, AJ Bos, M
Citation: H. Stadler et al., Structure-activity relationships of substituted 2,3,4,4a,5,10b-hexahydro-benz[h]isoquinoline-6(1H)-ones as 5-HT2C receptor antagonists, CHIMIA, 54(11), 2000, pp. 669-671
Brain 5-HT2C receptors: Potential role in anxiety disorders
Authors: Jenck, F Moreau, JL Wichmann, J Stadler, H Martin, JR Bos, M
Citation: F. Jenck et al., Brain 5-HT2C receptors: Potential role in anxiety disorders, MIL DRUG TH, 2000, pp. 119-137
A short and efficient synthesis of (2S,2 ' R,3 ' R)-2-(2 ',3 '-dicarboxylcyclopropyl)glycine (DCG-IV)
Authors: Wichmann, J Adam, G
Citation: J. Wichmann et G. Adam, A short and efficient synthesis of (2S,2 ' R,3 ' R)-2-(2 ',3 '-dicarboxylcyclopropyl)glycine (DCG-IV), EUR J ORG C, (11), 1999, pp. 3131-3133
8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivativesas orphanin FQ receptor agonists
Authors: Wichmann, J Adam, G Rover, S Cesura, AM Dautzenberg, FM Jenck, F
Citation: J. Wichmann et al., 8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivativesas orphanin FQ receptor agonists, BIOORG MED, 9(16), 1999, pp. 2343-2348
Synthesis of heterocyclic enol ethers and their use as group 2 metabotropic glutamate receptor antagonists
Authors: Kolczewski, S Adam, G Stadler, H Mutel, V Wichmann, J Woltering, T
Citation: S. Kolczewski et al., Synthesis of heterocyclic enol ethers and their use as group 2 metabotropic glutamate receptor antagonists, BIOORG MED, 9(15), 1999, pp. 2173-2176
Structure-activity relationships of substituted 5H-thiazolo [3,2-a]pyrimidines as group 2 metabotropic glutamate receptor antagonists
Authors: Wichmann, J Adam, G Kolczewski, S Mutel, V Woltering, T
Citation: J. Wichmann et al., Structure-activity relationships of substituted 5H-thiazolo [3,2-a]pyrimidines as group 2 metabotropic glutamate receptor antagonists, BIOORG MED, 9(11), 1999, pp. 1573-1576
Risultati: 1-16 |