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Results: 1-25 | 26-29
Results: 1-25/29
THE ONE-RING OPEN HYDROLYSIS INTERMEDIATES OF THE CARDIOPROTECTIVE AGENT DEXRAZOXANE (ICRF-187) DO NOT INHIBIT THE GROWTH OF CHINESE-HAMSTER OVARY CELLS OR THE CATALYTIC ACTIVITY OF DNA TOPOISOMERASE-II
Authors: HASINOFF BB KUSCHAK TI FATTMAN CL YALOWICH JC
Citation: Bb. Hasinoff et al., THE ONE-RING OPEN HYDROLYSIS INTERMEDIATES OF THE CARDIOPROTECTIVE AGENT DEXRAZOXANE (ICRF-187) DO NOT INHIBIT THE GROWTH OF CHINESE-HAMSTER OVARY CELLS OR THE CATALYTIC ACTIVITY OF DNA TOPOISOMERASE-II, Anti-cancer drugs, 9(5), 1998, pp. 465-471
MITINDOMIDE IS A CATALYTIC INHIBITOR OF DNA TOPOISOMERASE-II THAT ACTS AT THE BISDIOXOPIPERAZINE BINDING-SITE
Authors: HASINOFF BB CREIGHTON AM KOZLOWSKA H THAMPATTY P ALLAN WP YALOWICH JC
Citation: Bb. Hasinoff et al., MITINDOMIDE IS A CATALYTIC INHIBITOR OF DNA TOPOISOMERASE-II THAT ACTS AT THE BISDIOXOPIPERAZINE BINDING-SITE, Molecular pharmacology, 52(5), 1997, pp. 839-845
NITRIC-OXIDE PREVENTS OXIDATIVE DAMAGE PRODUCED BY TERT-BUTYL HYDROPEROXIDE IN ERYTHROLEUKEMIA-CELLS VIA NITROSYLATION OF HEME AND NONHEME IRON - ELECTRON-PARAMAGNETIC-RESONANCE EVIDENCE
Authors: GORBUNOV NV YALOWICH JC GADDAM A THAMPATTY P RITOV VB KISIN ER ELSAYED NM KAGAN VE
Citation: Nv. Gorbunov et al., NITRIC-OXIDE PREVENTS OXIDATIVE DAMAGE PRODUCED BY TERT-BUTYL HYDROPEROXIDE IN ERYTHROLEUKEMIA-CELLS VIA NITROSYLATION OF HEME AND NONHEME IRON - ELECTRON-PARAMAGNETIC-RESONANCE EVIDENCE, The Journal of biological chemistry, 272(19), 1997, pp. 12328-12341
CHEMICAL SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A NOVEL FLUORESCENT ETOPOSIDE DERIVATIVE
Authors: LAZO JS LI TH WOO ES SETTINERI CE ALLAN WP YALOWICH JC
Citation: Js. Lazo et al., CHEMICAL SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A NOVEL FLUORESCENT ETOPOSIDE DERIVATIVE, Biochemical pharmacology, 53(5), 1997, pp. 715-722
CHARACTERIZATION OF A CHINESE-HAMSTER OVARY CELL-LINE WITH ACQUIRED-RESISTANCE TO THE BISDIOXOPIPERAZINE DEXRAZOXANE (ICRF-187) CATALYTIC INHIBITOR OF TOPOISOMERASE-II
Authors: HASINOFF BB KUSCHAK TI CREIGHTON AM FATTMAN CL ALLAN WP THAMPATTY P YALOWICH JC
Citation: Bb. Hasinoff et al., CHARACTERIZATION OF A CHINESE-HAMSTER OVARY CELL-LINE WITH ACQUIRED-RESISTANCE TO THE BISDIOXOPIPERAZINE DEXRAZOXANE (ICRF-187) CATALYTIC INHIBITOR OF TOPOISOMERASE-II, Biochemical pharmacology, 53(12), 1997, pp. 1843-1853
THE EFFECT OF DEXRAZOXANE (ICRF-187) ON DOXORUBICIN-MEDIATED AND DAUNORUBICIN-MEDIATED GROWTH-INHIBITION OF CHINESE-HAMSTER OVARY CELLS
Authors: HASINOFF BB YALOWICH JC LING YZ BUSS JL
Citation: Bb. Hasinoff et al., THE EFFECT OF DEXRAZOXANE (ICRF-187) ON DOXORUBICIN-MEDIATED AND DAUNORUBICIN-MEDIATED GROWTH-INHIBITION OF CHINESE-HAMSTER OVARY CELLS, Anti-cancer drugs, 7(5), 1996, pp. 558-567
NITROSYLATION OF HEMOGLOBIN PREVENTS ALKYLHYDROPEROXIDE-INDUCED OXIDATIVE STRESS IN ERYTHROLEUKEMIA-CELLS
Authors: GORBUNOV NV ELSAYED NM KISIN ER RITOV VB GADDAM A ALLAN WP YALOWICH JC KAGAN VE
Citation: Nv. Gorbunov et al., NITROSYLATION OF HEMOGLOBIN PREVENTS ALKYLHYDROPEROXIDE-INDUCED OXIDATIVE STRESS IN ERYTHROLEUKEMIA-CELLS, The FASEB journal, 10(3), 1996, pp. 1160-1160
EXOGENOUS AND ENDOGENOUS NITRIC-OXIDE (NO-CENTER-DOT) PROTECTS AGAINST TERT-BUTYL HYDROPEROXIDE (TBH)-INDUCED CYTOTOXICITY IN HUMAN LEUKEMIA K562 CELLS - ROLE OF INTRACELLULAR HEMOGLOBIN (HB)
Authors: YALOWICH JC ALLAN WP MAWHINNEY BJ AKANO R THAMPATTY P KOZLOV A KAGAN VE
Citation: Jc. Yalowich et al., EXOGENOUS AND ENDOGENOUS NITRIC-OXIDE (NO-CENTER-DOT) PROTECTS AGAINST TERT-BUTYL HYDROPEROXIDE (TBH)-INDUCED CYTOTOXICITY IN HUMAN LEUKEMIA K562 CELLS - ROLE OF INTRACELLULAR HEMOGLOBIN (HB), The FASEB journal, 10(3), 1996, pp. 4071-4071
REDUCTION OF PHENOXYL RADICALS OF THE ANTITUMOR AGENT ETOPOSIDE (VP-16) BY GLUTATHIONE AND PROTEIN SULFHYDRYLS IN HUMAN LEUKEMIA-CELLS - IMPLICATIONS FOR CYTOTOXICITY
Authors: YALOWICH JC TYURINA YY TYURIN VA ALLAN WP KAGAN VE
Citation: Jc. Yalowich et al., REDUCTION OF PHENOXYL RADICALS OF THE ANTITUMOR AGENT ETOPOSIDE (VP-16) BY GLUTATHIONE AND PROTEIN SULFHYDRYLS IN HUMAN LEUKEMIA-CELLS - IMPLICATIONS FOR CYTOTOXICITY, Toxicology in vitro, 10(1), 1996, pp. 59-68
GENESIS OF DISCRETE HIGHER-ORDER DNA FRAGMENTS IN APOPTOTIC HUMAN PROSTATIC-CARCINOMA CELLS
Authors: RUSNAK JM CALMELS TPG HOYT DG KONDO Y YALOWICH JC LAZO JS
Citation: Jm. Rusnak et al., GENESIS OF DISCRETE HIGHER-ORDER DNA FRAGMENTS IN APOPTOTIC HUMAN PROSTATIC-CARCINOMA CELLS, Molecular pharmacology, 49(2), 1996, pp. 244-252
COLLATERAL SENSITIVITY TO THE BISDIOXOPIPERAZINE DEXRAZOXANE (ICRF-187) IN ETOPOSIDE (VP-16) RESISTANT HUMAN LEUKEMIA K562 CELLS
Authors: FATTMAN CL ALLAN WP HASINOFF BB YALOWICH JC
Citation: Cl. Fattman et al., COLLATERAL SENSITIVITY TO THE BISDIOXOPIPERAZINE DEXRAZOXANE (ICRF-187) IN ETOPOSIDE (VP-16) RESISTANT HUMAN LEUKEMIA K562 CELLS, Biochemical pharmacology, 52(4), 1996, pp. 635-642
NONRANDOM PEROXIDATION OF DIFFERENT CLASSES OF MEMBRANE PHOSPHOLIPIDSIN LIVE CELLS DETECTED BY METABOLICALLY INTEGRATED CIS-PARINARIC ACID
Authors: RITOV VB BANNI S YALOWICH JC DAY BW CLAYCAMP HG CORONGIU FP KAGAN VE
Citation: Vb. Ritov et al., NONRANDOM PEROXIDATION OF DIFFERENT CLASSES OF MEMBRANE PHOSPHOLIPIDSIN LIVE CELLS DETECTED BY METABOLICALLY INTEGRATED CIS-PARINARIC ACID, Biochimica et biophysica acta. Biomembranes, 1283(2), 1996, pp. 127-140
PHENOXYL RADICALS OF ETOPOSIDE (VP-16) CAN DIRECTLY OXIDIZE INTRACELLULAR THIOLS - PROTECTIVE VERSUS DAMAGING EFFECTS OF PHENOLIC ANTIOXIDANTS
Authors: TYURINA YY TYURIN VA YALOWICH JC QUINN PJ CLAYCAMP HG SCHOR NF PITT BR KAGAN VE
Citation: Yy. Tyurina et al., PHENOXYL RADICALS OF ETOPOSIDE (VP-16) CAN DIRECTLY OXIDIZE INTRACELLULAR THIOLS - PROTECTIVE VERSUS DAMAGING EFFECTS OF PHENOLIC ANTIOXIDANTS, Toxicology and applied pharmacology, 131(2), 1995, pp. 277-288
METALLOTHIONEIN PROTECTS AGAINST THE CYTOTOXIC AND DNA-DAMAGING EFFECTS OF NITRIC-OXIDE
Authors: SCHWARZ MA LAZO JS YALOWICH JC ALLEN WP WHITMORE M BERGONIA HA TZENG E BILLIAR TR ROBBINS PD LANCASTER JR PITT BR
Citation: Ma. Schwarz et al., METALLOTHIONEIN PROTECTS AGAINST THE CYTOTOXIC AND DNA-DAMAGING EFFECTS OF NITRIC-OXIDE, Proceedings of the National Academy of Sciences of the United Statesof America, 92(10), 1995, pp. 4452-4456
HYPOPHOSPHORYLATION OF TOPOISOMERASE-II IN ETOPOSIDE (VP-16)-RESISTANT HUMAN LEUKEMIA K562 CELLS ASSOCIATED WITH REDUCED LEVELS OF BETA(II)PROTEIN-KINASE-C
Authors: RITKE MK MURRAY NR ALLAN WP FIELDS AP YALOWICH JC
Citation: Mk. Ritke et al., HYPOPHOSPHORYLATION OF TOPOISOMERASE-II IN ETOPOSIDE (VP-16)-RESISTANT HUMAN LEUKEMIA K562 CELLS ASSOCIATED WITH REDUCED LEVELS OF BETA(II)PROTEIN-KINASE-C, Molecular pharmacology, 48(5), 1995, pp. 798-805
INDUCTION OF APOPTOSIS IN MURINE AND HUMAN NEUROBLASTOMA CELL-LINES BY THE ENEDIYNE NATURAL PRODUCT NEOCARZINOSTATIN
Authors: HARTSELL TL YALOWICH JC RITKE MK MARTINEZ AJ SCHOR NF
Citation: Tl. Hartsell et al., INDUCTION OF APOPTOSIS IN MURINE AND HUMAN NEUROBLASTOMA CELL-LINES BY THE ENEDIYNE NATURAL PRODUCT NEOCARZINOSTATIN, The Journal of pharmacology and experimental therapeutics, 275(1), 1995, pp. 479-485
A QSAR STUDY COMPARING THE CYTOTOXICITY AND DNA TOPOISOMERASE-II INHIBITORY EFFECTS OF BISDIOXOPIPERAZINE ANALOGS OF ICRF-187 (DEXRAZOXANE)
Authors: HASINOFF BB KUSCHAK TI YALOWICH JC CREIGHTON AM
Citation: Bb. Hasinoff et al., A QSAR STUDY COMPARING THE CYTOTOXICITY AND DNA TOPOISOMERASE-II INHIBITORY EFFECTS OF BISDIOXOPIPERAZINE ANALOGS OF ICRF-187 (DEXRAZOXANE), Biochemical pharmacology, 50(7), 1995, pp. 953-958
P-GLYCOPROTEIN MEDIATES PROFOUND RESISTANCE TO BISANTRENE
Authors: ZANG XP RITKE MK YALOWICH JC SLOVAK ML HO JP COLLINS KI ANNABLE T ARCECI RJ DURR FE GREENBERGER LM
Citation: Xp. Zang et al., P-GLYCOPROTEIN MEDIATES PROFOUND RESISTANCE TO BISANTRENE, Oncology research, 6(7), 1994, pp. 291-301
DIFFERENTIAL INDUCTION OF ETOPOSIDE-MEDIATED APOPTOSIS IN HUMAN LEUKEMIA HL-60 AND K562 CELLS
Authors: RITKE MK RUSNAK JM LAZO JS ALLAN WP DIVE C HEER S YALOWICH JC
Citation: Mk. Ritke et al., DIFFERENTIAL INDUCTION OF ETOPOSIDE-MEDIATED APOPTOSIS IN HUMAN LEUKEMIA HL-60 AND K562 CELLS, Molecular pharmacology, 46(4), 1994, pp. 605-611
REDUCED PHOSPHORYLATION OF TOPOISOMERASE-II IN ETOPOSIDE-RESISTANT HUMAN LEUKEMIA K562 CELLS
Authors: RITKE MK ALLAN WP FATTMAN C GUNDUZ NN YALOWICH JC
Citation: Mk. Ritke et al., REDUCED PHOSPHORYLATION OF TOPOISOMERASE-II IN ETOPOSIDE-RESISTANT HUMAN LEUKEMIA K562 CELLS, Molecular pharmacology, 46(1), 1994, pp. 58-66
INTERFERENCE BY DOXORUBICIN WITH DNA UNWINDING IN MCF-7 BREAST-TUMOR CELLS
Authors: FORNARI FA RANDOLPH JK YALOWICH JC RITKE MK GEWIRTZ DA
Citation: Fa. Fornari et al., INTERFERENCE BY DOXORUBICIN WITH DNA UNWINDING IN MCF-7 BREAST-TUMOR CELLS, Molecular pharmacology, 45(4), 1994, pp. 649-656
CYTOPLASMIC METALLOTHIONEIN OVEREXPRESSION PROTECTS NIH 3T3 CELLS FROM TERT-BUTYL HYDROPEROXIDE TOXICITY
Authors: SCHWARZ MA LAZO JS YALOWICH JC REYNOLDS I KAGAN VE TYURIN V KIM YM WATKINS SC PITT BR
Citation: Ma. Schwarz et al., CYTOPLASMIC METALLOTHIONEIN OVEREXPRESSION PROTECTS NIH 3T3 CELLS FROM TERT-BUTYL HYDROPEROXIDE TOXICITY, The Journal of biological chemistry, 269(21), 1994, pp. 15238-15243
ALTERED STABILITY OF ETOPOSIDE-INDUCED TOPOISOMERASE-II-DNA COMPLEXESIN RESISTANT HUMAN LEUKEMIA K562 CELLS
Authors: RITKE MK ROBERTS D ALLAN WP RAYMOND J BERGOLTZ VV YALOWICH JC
Citation: Mk. Ritke et al., ALTERED STABILITY OF ETOPOSIDE-INDUCED TOPOISOMERASE-II-DNA COMPLEXESIN RESISTANT HUMAN LEUKEMIA K562 CELLS, British Journal of Cancer, 69(4), 1994, pp. 687-697
ASCORBATE IS THE PRIMARY REDUCTANT OF THE PHENOXYL RADICAL OF ETOPOSIDE IN THE PRESENCE OF THIOLS BOTH IN CELL HOMOGENATES AND IN MODEL SYSTEMS
Authors: KAGAN VE YALOWICH JC DAY BW GOLDMAN R GANTCHEV TG STOYANOVSKY DA
Citation: Ve. Kagan et al., ASCORBATE IS THE PRIMARY REDUCTANT OF THE PHENOXYL RADICAL OF ETOPOSIDE IN THE PRESENCE OF THIOLS BOTH IN CELL HOMOGENATES AND IN MODEL SYSTEMS, Biochemistry, 33(32), 1994, pp. 9651-9660
INCREASED C-JUN AP-1 LEVELS IN ETOPOSIDE-RESISTANT HUMAN LEUKEMIA K562 CELLS/
Authors: RITKE MK BERGOLTZ VV ALLAN WP YALOWICH JC
Citation: Mk. Ritke et al., INCREASED C-JUN AP-1 LEVELS IN ETOPOSIDE-RESISTANT HUMAN LEUKEMIA K562 CELLS/, Biochemical pharmacology, 48(3), 1994, pp. 525-533
Risultati: 1-25 | 26-29