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Results: 1-25 | 26-31
Results: 1-25/31
L-162,389 - A POTENT ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONISTWITH BALANCED AFFINITY TO BOTH AT(1) AND AT(2) RECEPTOR SUBTYPES
Authors: RIVERO RA KEVIN NJ KIVLIGHN SD ZINGARO GJ CHANG RS GREENLEE WJ
Citation: Ra. Rivero et al., L-162,389 - A POTENT ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONISTWITH BALANCED AFFINITY TO BOTH AT(1) AND AT(2) RECEPTOR SUBTYPES, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 307-310
IN-VIVO PHARMACOLOGY OF L-159,913, A NEW HIGHLY POTENT AND SELECTIVE NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONIST
Authors: GABEL RA KIVLIGHN SD ZINGARO GJ SCHORN TW SCHAFFER LW ASHTON WT CHANG LL FLANAGAN K GREENLEE WJ SIEGL PKS
Citation: Ra. Gabel et al., IN-VIVO PHARMACOLOGY OF L-159,913, A NEW HIGHLY POTENT AND SELECTIVE NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONIST, Clinical and experimental hypertension, 17(6), 1995, pp. 931-953
AT(1) SELECTIVE ANGIOTENSIN-II ANTAGONISTS WITH PHENOXYPHENYLACETIC ACID AS A BIPHENYL REPLACEMENT .1.
Authors: FITCH KJ WALSH TF PATCHETT AA CHANG RSL SIEGL PKS FAUST KA CHEN TB LOTTI VJ KIVLIGHN SD ZINGARO GJ GREENLEE WJ
Citation: Kj. Fitch et al., AT(1) SELECTIVE ANGIOTENSIN-II ANTAGONISTS WITH PHENOXYPHENYLACETIC ACID AS A BIPHENYL REPLACEMENT .1., Bioorganic & medicinal chemistry letters, 5(2), 1995, pp. 155-158
THE SAR OF -2-PROPYL-3-[(2'-TETRAZOL-5-YL)BIPHEN-4-YL)METHYL] QUINAZOLINONES AS BALANCED AFFINITY ANTAGONISTS OF THE HUMAN AT(1) AND AT(2) RECEPTORS
Authors: DELASZLO SE CHANG RS CHEN TB FAUST KA GREENLEE WJ KIVLIGHN SD LOTTI VJ OMALLEY SS SCHORN TW SIEGL PK TRAN J ZINGARO GJ
Citation: Se. Delaszlo et al., THE SAR OF -2-PROPYL-3-[(2'-TETRAZOL-5-YL)BIPHEN-4-YL)METHYL] QUINAZOLINONES AS BALANCED AFFINITY ANTAGONISTS OF THE HUMAN AT(1) AND AT(2) RECEPTORS, Bioorganic & medicinal chemistry letters, 5(13), 1995, pp. 1359-1364
ALPHA-PHENOXYPHENYLACETIC ACID-DERIVED ANGIOTENSIN-II ANTAGONISTS WITH LOW NANOMOLAR AT(1) AT(2) RECEPTOR SUBTYPE AFFINITY .2./
Authors: WALSH TF KIVLIGHN SD ZINGARO GJ FITCH KJ CHANG RSL FAUST KA CHEN TB LOTTI VJ SIEGL PKS PATCHETT AA GREENLEE WJ
Citation: Tf. Walsh et al., ALPHA-PHENOXYPHENYLACETIC ACID-DERIVED ANGIOTENSIN-II ANTAGONISTS WITH LOW NANOMOLAR AT(1) AT(2) RECEPTOR SUBTYPE AFFINITY .2./, Bioorganic & medicinal chemistry letters, 5(11), 1995, pp. 1151-1154
IN-VIVO PHARMACOLOGY OF A NOVEL AT(1) SELECTIVE ANGIOTENSIN-II RECEPTOR ANTAGONIST, MK-996
Authors: KIVLIGHN SD ZINGARO GJ GABEL RA BROTEN TP SCHORN TW SCHAFFER LW NAYLOR EM CHAKRAVARTY PK PATCHETT AA GREENLEE WJ SIEGL PKS
Citation: Sd. Kivlighn et al., IN-VIVO PHARMACOLOGY OF A NOVEL AT(1) SELECTIVE ANGIOTENSIN-II RECEPTOR ANTAGONIST, MK-996, American journal of hypertension, 8(1), 1995, pp. 58-66
DISCOVERY OF L-162,313 - A NONPEPTIDE THAT MIMICS THE BIOLOGICAL ACTIONS OF ANGIOTENSIN-II
Authors: KIVLIGHN SD HUCKLE WR ZINGARO GJ RIVERO RA LOTTI VJ CHANG RSL SCHORN TW KEVIN N JOHNSON RG GREENLEE WJ SIEGL PKS
Citation: Sd. Kivlighn et al., DISCOVERY OF L-162,313 - A NONPEPTIDE THAT MIMICS THE BIOLOGICAL ACTIONS OF ANGIOTENSIN-II, American journal of physiology. Regulatory, integrative and comparative physiology, 37(3), 1995, pp. 820-823
PHARMACOLOGY OF L-754,142, A HIGHLY POTENT, ORALLY-ACTIVE, NONPEPTIDYL ENDOTHELIN ANTAGONIST
Authors: WILLIAMS DL MURPHY KL NOLAN NA OBRIEN JA PETTIBONE DJ KIVLIGHN SD KRAUSE SM LIS EV ZINGARO GJ GABEL RA CLAYTON FC SIEGL PKS ZHANG K NAUE J VYAS K WALSH TF FITCH KJ CHAKRAVARTY PK GREENLEE WJ CLINESCHMIDT BV
Citation: Dl. Williams et al., PHARMACOLOGY OF L-754,142, A HIGHLY POTENT, ORALLY-ACTIVE, NONPEPTIDYL ENDOTHELIN ANTAGONIST, The Journal of pharmacology and experimental therapeutics, 275(3), 1995, pp. 1518-1526
POTENT AND ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUAL AFFINITY FOR HUMAN AT(1) AND AT(2) SUBTYPES
Authors: CHANG LL ASHTON WT FLANAGAN KL CHEN TB OMALLEY SS ZINGARO GJ KIVLIGHN SD SIEGL PKS LOTTI VJ CHANG RSL GREENLEE WJ
Citation: Ll. Chang et al., POTENT AND ORALLY-ACTIVE ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUAL AFFINITY FOR HUMAN AT(1) AND AT(2) SUBTYPES, Journal of medicinal chemistry, 38(19), 1995, pp. 3741-3758
IN-VIVO PHARMACOLOGY OF AN ANGIOTENSIN AT(1) RECEPTOR ANTAGONIST WITHBALANCED AFFINITY FOR ANGIOTENSIN AT(2) RECEPTORS
Authors: KIVLIGHN SD ZINGARO GJ GABEL RA BROTEN TP CHANG RSL ONDEYKA DL MANTLO NB GIBSON RE GREENLEE WJ SIEGL PKS
Citation: Sd. Kivlighn et al., IN-VIVO PHARMACOLOGY OF AN ANGIOTENSIN AT(1) RECEPTOR ANTAGONIST WITHBALANCED AFFINITY FOR ANGIOTENSIN AT(2) RECEPTORS, European journal of pharmacology, 294(2-3), 1995, pp. 439-450
POTENT TRIAZOLINONE-BASED ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUIVALENT AFFINITY FOR BOTH THE AT(1) AND AT(2) SUBTYPES
Authors: CHANG LL ASHTON WT FLANAGAN KL RIVERO RA CHEN TB OMALLEY SS ZINGARO GJ KIVLIGHN SD SIEGL PKS LOTTI VJ CHANG RSL GREENLEE WJ
Citation: Ll. Chang et al., POTENT TRIAZOLINONE-BASED ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH EQUIVALENT AFFINITY FOR BOTH THE AT(1) AND AT(2) SUBTYPES, Bioorganic & medicinal chemistry letters, 4(23), 1994, pp. 2787-2792
DEVELOPMENT OF ANGIOTENSIN-II ANTAGONISTS WITH EQUIPOTENT AFFINITY FOR HUMAN AT(1) AND AT(2) RECEPTOR SUBTYPES
Authors: GLINKA TW DELASZLO SE SIEGL PKS CHANG RS KIVLIGHN SD SCHORN TS FAUST KA CHEN TB ZINGARO GJ LOTTI VJ GREENLEE WJ
Citation: Tw. Glinka et al., DEVELOPMENT OF ANGIOTENSIN-II ANTAGONISTS WITH EQUIPOTENT AFFINITY FOR HUMAN AT(1) AND AT(2) RECEPTOR SUBTYPES, Bioorganic & medicinal chemistry letters, 4(19), 1994, pp. 2337-2342
POTENT IMIDAZOLE ANGIOTENSIN-II ANTAGONISTS - ACYL SULFONAMIDES AND ACYL SULFAMIDES AS TETRAZOLE REPLACEMENTS
Authors: NAYLOR EM CHAKRAVARTY PK COSTELLO CA CHANG RS CHEN TB FAUST KA LOTTI VJ KIVLIGHN SD ZINGARO GJ SIEGL PKS WONG PC CARINI DJ WEXLER RR PATCHETT AA GREENLEE WJ
Citation: Em. Naylor et al., POTENT IMIDAZOLE ANGIOTENSIN-II ANTAGONISTS - ACYL SULFONAMIDES AND ACYL SULFAMIDES AS TETRAZOLE REPLACEMENTS, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 69-74
QUINAZOLINONE BIPHENYL ACYLSULFONAMIDES - A POTENT NEW CLASS OF ANGIOTENSIN-II RECEPTOR ANTAGONISTS
Authors: CHAKRAVARTY PK STRELITZ RA CHEN TB CHANG RSL LOTTI VJ ZINGARO GJ SCHORN TW KIVLIGHN SD SIEGL PKS PATCHETT AA GREENLEE WJ
Citation: Pk. Chakravarty et al., QUINAZOLINONE BIPHENYL ACYLSULFONAMIDES - A POTENT NEW CLASS OF ANGIOTENSIN-II RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 75-80
A NEW CLASS OF BALANCED AT(1) AT(2) ANGIOTENSIN-II ANTAGONISTS - QUINAZOLINONE AII ANTAGONISTS WITH ACYLSULFONAMIDE AND SULFONYLCARBAMATE ACIDIC FUNCTIONALITIES/
Authors: GLINKA TW DELASZLO SE SIEGL PKS CHANG RS KIVLIGHN SD SCHORN TS FAUST KA CHEN TB ZINGARO GJ LOTTI VJ GREENLEE WJ
Citation: Tw. Glinka et al., A NEW CLASS OF BALANCED AT(1) AT(2) ANGIOTENSIN-II ANTAGONISTS - QUINAZOLINONE AII ANTAGONISTS WITH ACYLSULFONAMIDE AND SULFONYLCARBAMATE ACIDIC FUNCTIONALITIES/, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 81-86
TRIAZOLINONES AS NONPEPTIDE ANGIOTENSIN-II ANTAGONISTS .2. DISCOVERY OF A POTENT AND ORALLY-ACTIVE TRIAZOLINONE ACYLSULFONAMIDE
Authors: CHANG LL ASHTON WT FLANAGAN KL NAYLOR EM CHAKRAVARTY PK PATCHETT AA GREENLEE WJ BENDESKY RJ CHEN TB FAUST KA KLING PJ SCHAFFER LW SCHORN TW ZINGARO GJ CHANG RSL LOTTI VJ KIVLIGHN SD SIEGL PKS
Citation: Ll. Chang et al., TRIAZOLINONES AS NONPEPTIDE ANGIOTENSIN-II ANTAGONISTS .2. DISCOVERY OF A POTENT AND ORALLY-ACTIVE TRIAZOLINONE ACYLSULFONAMIDE, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 115-120
ACIDIC PHENOLS - A NEW CLASS OF POTENT NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS
Authors: KIM D MANTLO NB TATA JR DHANOA D FITCH K OWENS K LEVORSE D SIEGL PKS CHANG RSL SCHECK S ZINGARO GJ KIVLIGHN SD GREENLEE WJ CHEN T
Citation: D. Kim et al., ACIDIC PHENOLS - A NEW CLASS OF POTENT NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 4(1), 1994, pp. 207-212
L-162,313, A NONPEPTIDE THAT MIMICS THE ACTION OF ANGIOTENSIN-II IN-VIVO
Authors: KIVLIGHN SD ZINGARO GJ RIVERO RA SCHORN TW CHANG RL LOTTI VJ KEVIN N GREENLEE WJ SIEGL PKS
Citation: Sd. Kivlighn et al., L-162,313, A NONPEPTIDE THAT MIMICS THE ACTION OF ANGIOTENSIN-II IN-VIVO, The FASEB journal, 8(5), 1994, pp. 10000879-10000879
IN-VIVO PHARMACOLOGY AND ANTIHYPERTENSIVE ACTIVITY OF L-159,282 (MK-996) A NONPEPTIDE ANGIOTENSIN-II (A-II) RECEPTOR ANTAGONIST
Authors: SIEGL PKS GABEL RA ZINGARO GJ SCHORN T HARVEY C ARBEGAST P BROTEN TP SCHAFFER LW CHAKRAVARTY PK GREENLEE W NAVLOR E PATCHETT AA KIVLIGHN SD
Citation: Pks. Siegl et al., IN-VIVO PHARMACOLOGY AND ANTIHYPERTENSIVE ACTIVITY OF L-159,282 (MK-996) A NONPEPTIDE ANGIOTENSIN-II (A-II) RECEPTOR ANTAGONIST, The FASEB journal, 8(5), 1994, pp. 10000881-10000881
NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS .2. DESIGN, SYNTHESIS,AND BIOLOGICAL-ACTIVITY OF N-SUBSTITUTED (PHENYLAMINO)PHENYLACETIC ACIDS AND ACYL SULFONAMIDES (VOL 36, PG 4241, 1993)
Authors: DHANOA DS BAGLEY SW CHANG RSL LOTTI VJ CHEN TB KIVLIGHN SD ZINGARO GJ SIEGL PKS PATCHETT AA GREENLEE WJ
Citation: Ds. Dhanoa et al., NONPEPTIDE ANGIOTENSIN-II RECEPTOR ANTAGONISTS .2. DESIGN, SYNTHESIS,AND BIOLOGICAL-ACTIVITY OF N-SUBSTITUTED (PHENYLAMINO)PHENYLACETIC ACIDS AND ACYL SULFONAMIDES (VOL 36, PG 4241, 1993), Journal of medicinal chemistry, 37(7), 1994, pp. 1034-1034
TRIAZOLINONE BIPHENYLSULFONAMIDES AS ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH HIGH-AFFINITY FOR BOTH THE AT(1) AND AT(2) SUBTYPES
Authors: CHANG LL ASHTON WT FLANAGAN KL CHEN TB OMALLEY SS ZINGARO GJ SIEGL PKS KIVLIGHN SD LOTTI VJ CHANG RSL GREENLEE WJ
Citation: Ll. Chang et al., TRIAZOLINONE BIPHENYLSULFONAMIDES AS ANGIOTENSIN-II RECEPTOR ANTAGONISTS WITH HIGH-AFFINITY FOR BOTH THE AT(1) AND AT(2) SUBTYPES, Journal of medicinal chemistry, 37(26), 1994, pp. 4464-4478
A HIGHLY POTENT, ORALLY-ACTIVE IMIDAZO[4,5-B]PYRIDINE BIPHENYLACYLSULFONAMIDE (MK-996-L-159,282) - A NEW ANGIOTENSIN-II RECEPTOR ANTAGONIST
Authors: CHAKRAVARTY PK NAYLOR EM CHEN A CHANG RSL CHEN TB FAUST KA LOTTI VJ KIVLIGHN SD GABLE RA ZINGARO GJ SCHORN TW SCHAFFER LW BROTEN TP SIEGL PKS PATCHETT AA GREENLEE WJ
Citation: Pk. Chakravarty et al., A HIGHLY POTENT, ORALLY-ACTIVE IMIDAZO[4,5-B]PYRIDINE BIPHENYLACYLSULFONAMIDE (MK-996-L-159,282) - A NEW ANGIOTENSIN-II RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 37(24), 1994, pp. 4068-4072
TRIAZOLINONE BIPHENYLSULFONAMIDE DERIVATIVES AS ORALLY-ACTIVE ANGIOTENSIN-II ANTAGONISTS WITH POTENT AT(1) RECEPTOR AFFINITY AND ENHANCED AT(2) AFFINITY
Authors: ASHTON WT CHANG LL FLANAGAN KL HUTCHINS SM NAYLOR EM CHAKRAVARTY PK PATCHETT AA GREENLEE WJ CHEN TB FAUST KA CHANG RSL LOTTI VJ ZINGARO GJ SCHORN TW SIEGL PKS KIVLIGHN SD
Citation: Wt. Ashton et al., TRIAZOLINONE BIPHENYLSULFONAMIDE DERIVATIVES AS ORALLY-ACTIVE ANGIOTENSIN-II ANTAGONISTS WITH POTENT AT(1) RECEPTOR AFFINITY AND ENHANCED AT(2) AFFINITY, Journal of medicinal chemistry, 37(17), 1994, pp. 2808-2824
QUINAZOLINONES-2 - QSAR AND INVIVO CHARACTERIZATION OF AT1 SELECTIVE AII ANTAGONISTS
Authors: DELASZLO SE ALLEN EE QUAGLIATO CS GREENLEE WJ PATCHETT AA NACHBAR RB SIEGL PKS CHANG RS KIVLIGHN SD SCHORN TS FAUST KA CHEN TB ZINGARO GJ LOTTI VJ
Citation: Se. Delaszlo et al., QUINAZOLINONES-2 - QSAR AND INVIVO CHARACTERIZATION OF AT1 SELECTIVE AII ANTAGONISTS, Bioorganic & medicinal chemistry letters, 3(6), 1993, pp. 1299-1304
CARDIAC ELECTROPHYSIOLOGIC AND ANTIARRHYTHMIC ACTIONS OF 3,4-DIHYDRO-1'-[2-(BENZOFURAZAN-5-YL) AMIDOSPIRO[(2H)-1-BENZOPYRAN-2,4'-PIPERIDIN]-4-ONE HCL (L-691, 121), A NOVEL CLASS-III AGENT
Authors: LYNCH JJ WALLACE AA VANDERGAAG LH BASKIN EP BEAR CM GEHRET JR KOTHSTEIN T STUPIENSKI RF APPLEBY SD SANGUINETTI MC JURKIEWICZ NK ZINGARO GJ STEIN RB CLAREMON DA ELLIOTT JM YOUNG MB BALDWIN JJ
Citation: Jj. Lynch et al., CARDIAC ELECTROPHYSIOLOGIC AND ANTIARRHYTHMIC ACTIONS OF 3,4-DIHYDRO-1'-[2-(BENZOFURAZAN-5-YL) AMIDOSPIRO[(2H)-1-BENZOPYRAN-2,4'-PIPERIDIN]-4-ONE HCL (L-691, 121), A NOVEL CLASS-III AGENT, The Journal of pharmacology and experimental therapeutics, 265(2), 1993, pp. 720-730
Risultati: 1-25 | 26-31