INTESTINAL PASSAGE OF LACTOBACILLUS-RHAMNOSUS DSM-6594 AFTER ORAL-ADMINISTRATION IN FERMENTED MILK

Seventeen volunteers consumed 200 ml of the fermented milk, Prima Liv( TM), daily for 21 d. The fermented milk was produced with a mixed star ter culture Streptococcus thermophilus MSKB3/1, Lactobacillus lactis L actobacillus acidophilus MSKB3/3 and Bifidobacterium sp. MSKB3/4, and Lactobacillus rhamnosus DSM 6594. The administered product contained 8 x 10(7) cfu of Lb. rhamnosus DSM 6594 ml(-1). Lactobacillus rhamnosus DSM 6594 was recovered as a substantial part of the lactobacilli flor a from faeces of sixteen of the volunteers after 7 d of administration , and in three volunteers, 7 d after the end of the administration per iod. The faecal counts of lactobacilli were significantly increased af ter 7 d of administration, and the effect remained 7 d after the end o f administration. None of the volunteers experienced any negative side effects by the consumption.