Foodborne outbreaks of listeriosis caused by Listeria monocytogenes ha
ve contributed to public consciousness about bacterial pathogens invol
ved with foodborne disease. Major concerns with L. monocytogenes are i
ts high mortality rate, wide distribution on products. growth at low t
emperatures, and its ability to establish itself in various food-proce
ssing environments. These concerns have prompted the examination of no
vel approaches, including the use of antimicrobial peptides. or bacter
iocins, to combat its survival in foods. Bacteriocins from lactic acid
bacteria have received much attention because these microorganisms ha
ve a long history of safe use in foods either as starter cultures or a
s indigenous contaminants. Some bacteriocins are inhibitory to foodbor
ne pathogens, including Listeria spp., a substantial reason for invest
igating their potential use in novel food preservation applications. N
isin is currently accepted worldwide and in the U.S.; however, numerou
s other bacteriocins also have potential use in similar applications.
Recent examples suggest that bacteriocins may contribute an additional
barrier in the ''hurdle'' concept of food safety.