FURTHER DEVELOPMENT OF METHODS ACCORDING TO DFG AND DIN-32645 WITH RESPECT TO ANALYTIC PRACTICE

In this concept detection limit (DL) and identification limit (IL) are derived as in DIN 32645. For the quantification limit (QL) a new appr oach is presented that takes account of elements of a concept of Deuts che Forschungsgemeinschaft in the field of residue analysis. Primary i mportance is given to the variability of analytical signals around the calibration line in a very low concentration range. This variability is represented by the prediction interval (for a probability of 95%) o f the line. - Several practical hints and a detailed calculation examp le illustrate this concept further.