Four lines of turkeys, a randombred control (RBC2) started in 1966 and
three sire lines (F, A, and B), were challenged with a field isolate
of Pasteurella multocida (capsular serogroup A, somatic serotype 3, 4)
at 6 wk of age. Line F, a subline of the RBC2 line, was selected for
28 generations for increased 16-wk BW and Lines A and B were primary b
reeding sire lines from two commercial breeders. Each bird was inocula
ted subcutaneously in the back of the neck with 1.2 x 10(7) washed bac
teria. Mortality following challenge with P. multocida was higher in t
he sire lines (54 to 65%) than in the RBC2 line (26%). There was no si
gnificant difference in mortality among sire lines following challenge
. These results suggest that the increased susceptibility to P. multoc
ida in the F line in comparison to its control may be due to genetic c
hanges resulting from selection for increased BW in this line.