MICROBIAL TRANSFORMATION OF 12-HYDROXYOCTADECANOIC ACID TO 5-N-HEXYL-TETRAHYDROFURAN-2-ACETIC ACID

Authors
HUANG JK KEUDELL KC ZHAO J KLOPFENSTEIN WE WEN L BAGBY MO LANSER AC PLATTNER RD PETERSON RE ABBOTT TP WEISLEDER D
Citation
Jk. Huang et al., MICROBIAL TRANSFORMATION OF 12-HYDROXYOCTADECANOIC ACID TO 5-N-HEXYL-TETRAHYDROFURAN-2-ACETIC ACID, Journal of the American Oil Chemists' Society, 72(3), 1995, pp. 323-326
Citations number
25
Categorie Soggetti
Food Science & Tenology","Chemistry Applied
Journal title
Journal of the American Oil Chemists' Society → ACNP
ISSN journal
0003021X
Volume
72
Issue
3
Year of publication
1995
Pages
323 - 326
Database
ISI
SICI code
0003-021X(1995)72:3<323:MTO1AT>2.0.ZU;2-S
Abstract
Stationary-phase cells of a corynebacterium (FUI-2) and a bacillus (NR RL B-14864) isolate, when grown aerobically in 1% YE medium at 25 degr ees C, converted 12-hydroxystearic acid to a major compound, 5-n-hexyl -tetrahydrofuran-2-acetic acid, and other intermediate and minor compo unds (6-hydroxydodecanoic acid, 4-hydroxydecanoic acid, 4-ketodecanoic acid and gamma-decanolactone). The yields of 5-n-hexyl-tetrahydrofura n-2-acetic acid, 4-hydroxydecanoic acid, and gamma-decanolactone, by B acillus lentus NRRL B-14864 were 43%, 18% and 5%, respectively, after 2.5 d of incubation.