FECAL RECOVERY FOLLOWING ORAL-ADMINISTRATION OF LACTOBACILLUS STRAIN GG (ATCC-53103) IN GELATIN CAPSULES TO HEALTHY-VOLUNTEERS

Recovery of the suggested probiotic strain Lactobacillus GG in feces w as studied after oral administration. Lactobacillus cc was given to 20 healthy human volunteers for 7 days in gelatine capsules with daily d oses of 1.6 x 10(8) cfu and 1.2 x 10(10) cfu. All the volunteers in th e higher dose group had detectable numbers of Lactobacillus GG in thei r feces during the test period. The strain was detected in feces of al l the volunteers after 3 days of administration. No effect was observe d on the total number of fecal lactobacilli. Fecal detection of the st rain may facilitate dose-response studies and provide a useful tool in dietary studies utilizing the strain in foods or food-type products.