CARBOHYDRATE-METABOLISM IN HEPATIC TISSUE OF FRESH-WATER CATFISH CLARIAS-BATRACHUS L DURING DIMETHOATE EXPOSURE

Clarias batrachus L., a freshwater catfish of commercial importance, w as exposed to a sublethal concentration of dimethoate (Rogor). The acu te effect of dimethoate on some aspects of carbohydrate metabolism of hepatic tissue was studied after 1, 2, 4 and 8 days. The glycogen cont ent was depleted, whereas the lactate level was elevated throughout th e experimental period and an increase in lactate dehydrogenase was obs erved. The activity levels of glycogen phosphorylase a and ab in the h epatic tissue were increased during dimethoate stress. The results sug gest that carbohydrate metabolism was adversely affected in the hepati c tissue by the organophosphate insecticide dimethoate.