Rpj. Vanderwielen et al., NUTRITIONAL-STATUS OF ELDERLY FEMALE NURSING-HOME RESIDENTS - THE EFFECT OF SUPPLEMENTATION WITH A PHYSIOLOGICAL DOSE OF WATER-SOLUBLE VITAMINS, European journal of clinical nutrition, 49(9), 1995, pp. 665-674
Objective: To assess the nutritional status of female elderly nursing
home residents and to study the effect of dietary supplementation with
a physiological dose of water-soluble vitamins. Design: Single-blind,
randomised, placebo-controlled intervention trial. Daily consumed sup
plement consisted of fortified fruit juice containing 50 g carbohydrat
e and 50% of the daily dietary recommendations of water-soluble vitami
ns. Regular fruit juice was used as placebo. Dietary intake assessment
at baseline. Fasting blood sample, anthropometric measurements and me
dical record at baseline and after 4 and 12 weeks of supplementation.
Setting: Three nursing homes within 40km of the coordination centre (D
epartment of Human Nutrition, Wageningen Agricultural University, the
Netherlands). Subjects: Forty-two female nursing home residents aged 6
0 years and older, in relatively stable health condition, at least 3 m
onths resident at baseline. In each nursing home, 14 subjects were ran
domly assigned to the supplement or control group. Interventions: Twel
ve weeks of supplementation. Results: Participants had a poor nutritio
nal status. Dietary supplementation significantly improved the concent
rations of thiamin pyrophosphate and pyridoxal 5'-phosphate, increased
body weight and decreased serum homocysteine concentration in the sup
plement group. Plasma vitamin C levels were significantly increased in
both supplement and control group. Conclusions: Even in this heteroge
neous population of female nursing home elderly it is possible to impr
ove the nutritional status through dietary intervention with a physiol
ogical dose of water-soluble vitamins.