Enterobacter sakazakii, previously referred to as a 'yellow-pigmented
Enterobacter cloacae', was designated as a unique species in 1980. Thi
s reclassification was based on differences from E. cloacae in DNA rel
atedness, pigment production and biochemical reactions. E. sakazakii h
as been implicated in a severe form of neonatal meningitis. Although s
tudies have failed to identify an environmental source for the organis
m, dried-infant formula has been implicated in both outbreaks and spor
adic cases of E. sakazakii meningitis. The high mortality rate (40-80%
), the severity of the infection in infants, plus the scarcity of info
rmation on the ecology and pathogenicity of this organism warranted a
review of the clinical and microbiological features of this putative f
oodborne pathogen.