Oxidation of food lipid components, known as oxidative rancidity is on
e of the major deteriorative and quality-affecting reactions. Oxidativ
e rancidity is initiated by oxygen free-radicals or by the reaction of
molecular oxygen with pre-formed organic free-radicals from polyunsat
urated fatty acids composing fats and oils. Oxidatian may be prevented
or delayed by antioxidants, these substances being organic molecules
of either synthetic or natural origin which can scavenge the oxygen fr
ee-radicals involved in fatty acid oxidation. Synthetic antioxidants a
re the most popular and widely used antioxidants, however concerns abo
ut it safe to both human and animal health is encouraging research on
substances from natural origin showing antioxidant properties. Few nat
ural antioxidants have been proved to be effective when compared to sy
nthetic products in the same experimental conditions. This work summar
izes the main characteristics of the most important synthetic antioxid
ants, also discuss the principal characteristics of four natural antio
xidants, comparing the advantages and disadvantages of using natural p
roducts compared to synthetic ones, and sight the future far natural p
roducts with antioxidant activity.