This article presents data from an ethnographic study of science techn
icians The article proposes a model of the science technician's role a
s broker in a serially interdependent occupational division of labor a
nd then contextualizes the model by examining how technicians conceptu
alize and manage troubles that arise in the course of scientific proce
dures. The data suggest that technicians possess most of a lab's conte
xtual knowledge and skill and that technicians, therefore, play a crit
ical role in the production of scientific knowledge. Because contextua
l knowledge carries less status than formal knowledge, however technic
ians experience status inconsistencies. The implications of such statu
s inconsistencies for the transition to an increasingly technical work
force are discussed.