This study examined the relative effects of two highly contrasting ear
ly intervention programs, Mediated Learning (ML) and Direct Instructio
n (DI), in a randomized design. Subjects were children (ages 3-7 years
) with mild to moderate disabilities in cognitive, language, socioemot
ional, and motor development. No main effect differences between the t
wo groups were found on a battery of cognitive, language, and motor me
asures. Aptitude-x-Treatment Interaction (ATI) analyses of pretest and
posttest results indicated that, contrary to conventional wisdom, rel
atively higher performing students gained more from DI, whereas relati
vely lower performing students gained more from ML. Although ATIs were
significant, the effect sizes were modest (3%-8% of variance) and do
not yet warrant major changes in educational practices.