DOSE-DEPENDENT GENOTOXIC EFFECT OF PAN MASALA AND ARECA NUT IN THE SALMONELLA-TYPHIMURIUM ASSAY

Authors
POLASA K BABU S SHENOLIKAR IS
Citation
K. Polasa et al., DOSE-DEPENDENT GENOTOXIC EFFECT OF PAN MASALA AND ARECA NUT IN THE SALMONELLA-TYPHIMURIUM ASSAY, Food and chemical toxicology, 31(6), 1993, pp. 439-442
Citations number
20
Categorie Soggetti
Toxicology,"Food Science & Tenology
Journal title
Food and chemical toxicology → ACNP
ISSN journal
02786915
Volume
31
Issue
6
Year of publication
1993
Pages
439 - 442
Database
ISI
SICI code
0278-6915(1993)31:6<439:DGEOPM>2.0.ZU;2-4
Abstract
Aqueous extracts of different brands of pan masala and scented supari were tested for mutagenicity by the Salmonella typhimurium assay using tester strains TA98 and TA100. These extracts were found to be mutage nic to both tester strains. The mutagenic effects of pan masala and sc ented supari extracts were similar to that produced by areca nut extra ct. The addition of 500 ppm saccharin to the supari extracts did not a lter the mutagenic response.