Pm. Krisetherton et D. Krummel, ROLE OF NUTRITION IN THE PREVENTION AND TREATMENT OF CORONARY HEART-DISEASE IN WOMEN, Journal of the American Dietetic Association, 93(9), 1993, pp. 987-993
Coronary heart disease (CHD) is the major cause of death in women. Bec
ause the manifestation of CHD differs in women and men (men are more l
ikely to have acute CHD and women are more likely to have chronic CHD)
, it is imperative to explore the unique aspects of CHD in women. In a
ddition, there is a critical need to increase our understanding of the
effect of CHD risk factor modification on coronary morbidity and mort
ality in women. Several major CHD risk factors in women, such as eleva
ted blood lipids and lipoproteins, body weight, and, frequently, hyper
tension, are beneficially responsive to nutrition intervention. Approx
imately 27% of all women and 50% of women aged 55 to 74 years are cand
idates for dietary intervention. The fact that women respond positivel
y to dietary intervention has been well established by researchers. St
udies are needed to determine the efficacy of risk factor modification
achieved by dietary and other hygienic approaches as well as by other
more rigorous therapies (eg, drugs and surgery) on the primary and se
condary prevention of CHD in women. Finally, it will be important to u
nderstand the effects of gender, menopausal status, and age on dietary
responsiveness. We must gain a better understanding of these issues s
o that we may significantly reduce the incidence of CHD in women.