FIA-FLUOROMETRIC ASSEMBLY FOR THE DETERMINATION OF NORADRENALINE HYDROCHLORIDE BY A SOLID-PHASE REACTOR WITH IMMOBILIZED HEXACYANOFERRATE(III)

An FIA assembly provided with immobilized hexacyanoferrate(III) is pro posed for the fluorimetric determination of noradrenaline hydrochlorid e. The oxidative reagent is immobilized by means of a strong anion-exc hange resin. The FIA manifold is very simple and the calibration graph is linear over the range 0.5-75 mg l(-1) noradrenaline hydrochloride with an r.s.d of 0.88% (17 replicates) and a sample throughput of 84 h (-1). Foreign compounds such as NaCl, sucrose, lactose and sodium sulf ate caused no significant errors. The procedure is applied to the dete rmination of noradrenaline in a medicinal formulation.