FIA-FLUOROMETRIC DETERMINATION OF ADRENALINE IN PHARMACEUTICAL FORMULATIONS BY OXIDATION WITH MOLECULAR-OXYGEN

Authors
TORRES AC ROMERO AM CALATAYUD JM
Citation
Ac. Torres et al., FIA-FLUOROMETRIC DETERMINATION OF ADRENALINE IN PHARMACEUTICAL FORMULATIONS BY OXIDATION WITH MOLECULAR-OXYGEN, Mikrochimica acta, 128(3-4), 1998, pp. 187-190
Citations number
14
Categorie Soggetti
Chemistry Analytical
Journal title
Mikrochimica acta → ACNP
ISSN journal
00263672
Volume
128
Issue
3-4
Year of publication
1998
Pages
187 - 190
Database
ISI
SICI code
0026-3672(1998)128:3-4<187:FDOAIP>2.0.ZU;2-I
Abstract
The fluorimetric determination of adrenaline is carried out in a conti nuous-flow assembly and by means of the molecular dissolved oxygen. Th e sample solution merges with an NaOH stream, then the resulting mixtu re is heated at 73 degrees C and led to the flow-cell of the fluorimet er. The flow-assembly is very simple and the procedure is quick (107 s amples h(-1)) reproducible (R.S.D. 0.6%), selective and suitable to be applied to determination of adrenaline in formulations. Calibrations graph are linear over the ranges 0.05-15 and 20-40 mg l(-1).