Objective: To assess the adequacy of the iodine supply in the Netherla
nds and to study possible ways of increasing the iodine intake. Design
, settings and subjects: Goitre and nutrition surveillance studies (in
take and urinary excretion of iodine) among population groups (age: 12
-85 y, n = 57-1704) in the Netherlands in the period 1981-1993. Simula
tion studies, based on the Dutch Nutrition Food Consumption Surveys (n
= 6000), calculating iodine intake among population groups after fict
ively iodizing different food groups. Results: Mean intake of iodine,
measured with different food consumption methods in the period 1984-19
93, met the recommended amount of 150-300 mu g per day in males, but n
ot in females. Median urinary iodine excretion levels were in the rang
e for mild Iodine Deficiency Disorders in both sexes. According to die
tary methods reflecting habitual intake and urinary iodine excretion p
er kg body weight or per mmol creatinin the prevalence of low iodine s
upply among adults is between 4 and 20% for women and between 5 and 15
% for men. Iodization of different products would increase mean iodine
intakes by up to 45% and would give a reduction of roughly 65% in the
prevalence of low iodine intakes. Conclusion: The present goitre prop
hylaxis in the Netherlands is not optimally effective. The iodine supp
ly is below cut-off points in 4-20% of the adult population. It is pos
sible to decrease the prevalence of low iodine intakes without a clear
risk of exceeding the maximum acceptable daily iodine intake by incre
asing the iodine content of baker's salt and/or by adding iodine to ot
her foods.