During 1995, 159 samples of mill;, 97 samples of dry mill: for infant
formula, and 114 samples of yogurt were randomly collected in supermar
kets and drug stores in four large Italian cities and checked for afla
toxin M-1 (AFM(1)) by immunoaffinity column extraction and HPLC. AFM(1
) was detected in 136 (86%) of the milk samples tin amounts ranging fr
om (1 ng/liter to 108.5 ng/liter; mean level: 10.19 ng/liter), in 81 (
84%) of Me dry milk samples tin amounts ranging from <1 ng/kg to 101.3
ng/kg; mean level: 21.77 ng/kg), and in 91 (80%) of the yogurt sample
s tin amounts ranging from <1 ng/liter to 496.5 ng/liter; mean level:
18.08 ng/liter). Altogether, only two samples of milk, two samples of
yogurt, and one sample of dry milk had levels of AFM(1) exceeding the
Swiss legal limits, which are the most restrictive in the world. AFM(1
) contamination levels in milk and yogurt samples collected in the per
iod of November to April were ca. four times as high as those in sampl
es collected in the period of May to October. Iris concluded that duri
ng 1995, despite the widespread occurrence of AFM(1), the mean contami
nation levels in dairy products sold in Italy were not a serious human
health hazard.