PHARMACOLOGICAL ACTIVITY OF THE FRACTION ISOLATED FROM VIRGIN OLIVE OIL CONTAINING THE STEROLS AND TRITERPENIC ALCOHOLS

Authors
DELAPUERTA R MAESTRODURAN R RUIZGUTIERREZ V
Citation
R. Delapuerta et al., PHARMACOLOGICAL ACTIVITY OF THE FRACTION ISOLATED FROM VIRGIN OLIVE OIL CONTAINING THE STEROLS AND TRITERPENIC ALCOHOLS, Grasas y aceites, 48(2), 1997, pp. 93-95
Citations number
7
Categorie Soggetti
Food Science & Tenology","Chemistry Applied
Journal title
Grasas y aceites → ACNP
ISSN journal
00173495
Volume
48
Issue
2
Year of publication
1997
Pages
93 - 95
Database
ISI
SICI code
0017-3495(1997)48:2<93:PAOTFI>2.0.ZU;2-2
Abstract
The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for its possible antiinflamatory activity. The topical administration of these products produced a pote nt antioedematous effect, in the auricular oedema induced by TPA (12-O -tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholip ase A, inhibitors. The measure of myeloperoxidase, marker enzyme of th e accumulation of neutrophils in the inflamed tissue, demonstrated a s ignificant reduction of the cellular infiltration produced by assayed fraction.