Although homeostatic mechanisms remain of utmost importance, rhythmic
changes are present also. The main ones have a period of 24 h (circadi
an) or about 2-3 h (ultradian). Circadian rhythms are derived from a b
ody clock, found in the base of the brain, and from the pattern of our
sleep wake cycle, including activity and meal times. These rhythms pr
omote the regular changes between an active wake period and a recupera
tive sleep period. Ultradian rhythms are also widespread and reflect e
xternal (lifestyle) and internal factors. The internal factors include
biochemical need and some sort of oscillator; but details of how many
oscillators, and exactly where they are, remain to be established. Fo
od intake, appetite, digestion and metabolism have been shown to illus
trate these principles. Moreover, these principles become important wh
en special circumstances exist as far as meal times are concerned; the
particular difficulties of night workers is a good example.