A high incidence of learning disabilities (LD) has been reported in ch
ildren with neurofibromatosis Type 1 (NF-1), and many children affecte
d with this disease are thought to have a form of LD that is character
ized by selective visuospatial and motor deficits. However, the eviden
ce is subject to sampling biases and is limited by the clinical-infere
ntial methods used to classify children into LD subtypes. In the prese
nt study, objective statistical methods were used to categorize LD in
105 children with NF-1 between the ages of 6 and 18 years. A cluster a
nalysis of achievement test scores yielded 10 groups, 6 of which met o
ur criterion for academic deficiency. An analysis of neuropsychologica
l data for 72 children with academic deficiencies with complete neurop
sychological data yielded three groups: a neuropsychologically normal
group (n = 28), a group with general academic deficiencies (n = 34), a
nd a soup with visuospatial-construction deficiencies (n = 10). The lo
w incidence of visuospatial-constructional deficits and the absence of
cases involving pure linguistic deficits is notable.