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Results: 1-12 |
Results: 12
NON PEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS - 2 - THE SYNTHESIS OF[H-3]L-738,167
Authors: HAMILL TG ASKEW BC HARTMAN GD CLAREMON DA MCINTYRE CJ BURNS HD
Citation: Tg. Hamill et al., NON PEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS - 2 - THE SYNTHESIS OF[H-3]L-738,167, Journal of labelled compounds & radiopharmaceuticals, 41(4), 1998, pp. 273-277
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .13. DESIGN AND SYNTHESISOF AN ORALLY-ACTIVE PYRAZOLOPIPERAZINONE NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONIST/
Authors: ASKEW BC MCINTYRE CJ HUNT CA CLAREMON DA BALDWIN JJ ANDERSON PS GOULD RJ LYNCH RJ CHANG CCT COOK JJ LYNCH JJ HOLAHAN MA SITKO GR STRANIERI MT
Citation: Bc. Askew et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .13. DESIGN AND SYNTHESISOF AN ORALLY-ACTIVE PYRAZOLOPIPERAZINONE NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONIST/, Bioorganic & medicinal chemistry letters, 7(12), 1997, pp. 1531-1536
KINETIC AND THERMODYNAMIC PARAMETERS OF RGD LIGANDS IN BINDING TO GPIIB IIIA ON PLATELETS/
Authors: CUNNIGHAM ME MCQUENEY PA EGBERTSON MS ASKEW BC BEDNAR RA HARTMAN GH GOULD RJ BEDNAR B
Citation: Me. Cunnigham et al., KINETIC AND THERMODYNAMIC PARAMETERS OF RGD LIGANDS IN BINDING TO GPIIB IIIA ON PLATELETS/, Thrombosis and haemostasis, 1997, pp. 2745-2745
EQUILIBRIUM AND DYNAMICS OF FIBRINOGEN RECEPTORS ON RESTING AND ACTIVATED PLATELETS AND IMPLICATIONS FOR THE SEPARATION OF EFFICACY AND BLEEDING-TIME
Authors: BEDNAR B BEDNAR RA MCQUENEY PA CUNNIGHAM ME EGBERTSON MS ASKEW BC COOK JJ HARTMAN GD GOULD RJ
Citation: B. Bednar et al., EQUILIBRIUM AND DYNAMICS OF FIBRINOGEN RECEPTORS ON RESTING AND ACTIVATED PLATELETS AND IMPLICATIONS FOR THE SEPARATION OF EFFICACY AND BLEEDING-TIME, Thrombosis and haemostasis, 1997, pp. 2757-2757
FLOW CYTOMETRIC MEASUREMENT OF KINETIC AND EQUILIBRIUM BINDING PARAMETERS OF ARGININE-GLYCINE-ASPARTIC ACID LIGANDS IN BINDING TO GLYCOPROTEIN IIB IIIA ON PLATELETS/
Authors: BEDNAR B CUNNINGHAM ME MCQUENEY PA EGBERTSON MS ASKEW BC BEDNAR RA HARTMAN GD GOULD RJ
Citation: B. Bednar et al., FLOW CYTOMETRIC MEASUREMENT OF KINETIC AND EQUILIBRIUM BINDING PARAMETERS OF ARGININE-GLYCINE-ASPARTIC ACID LIGANDS IN BINDING TO GLYCOPROTEIN IIB IIIA ON PLATELETS/, Cytometry, 28(1), 1997, pp. 58-65
DISPOSITION OF L-738,167, A POTENT AND LONG-ACTING FIBRINOGEN RECEPTOR ANTAGONIST, IN DOGS - DOSE-DEPENDENT PHARMACOKINETICS
Authors: PRUEKSARITANONT T GORHAM LM NAUE JA HAMILL TG ASKEW BC VYAS KP
Citation: T. Prueksaritanont et al., DISPOSITION OF L-738,167, A POTENT AND LONG-ACTING FIBRINOGEN RECEPTOR ANTAGONIST, IN DOGS - DOSE-DEPENDENT PHARMACOKINETICS, Drug metabolism and disposition, 25(3), 1997, pp. 355-361
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .15. ANTITHROMBOTIC EFFICACY OF L-738,167, A LONG-ACTING GPIIB/IIIA ANTAGONIST, CORRELATES WITHINHIBITION OF ADENOSINE DIPHOSPHATE-INDUCED PLATELET-AGGREGATION BUT NOT WITH BLEEDING-TIME PROLONGATION/
Authors: COOK JJ SITKO GR HOLAHAN MA STRANIERI MT GLASS JD ASKEW BC MCINTYRE CJ CLAREMON DA BALDWIN JJ HARTMAN GD GOULD RJ LYNCH JJ
Citation: Jj. Cook et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .15. ANTITHROMBOTIC EFFICACY OF L-738,167, A LONG-ACTING GPIIB/IIIA ANTAGONIST, CORRELATES WITHINHIBITION OF ADENOSINE DIPHOSPHATE-INDUCED PLATELET-AGGREGATION BUT NOT WITH BLEEDING-TIME PROLONGATION/, The Journal of pharmacology and experimental therapeutics, 281(2), 1997, pp. 677-689
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/
Authors: ASKEW BC BEDNAR RA BEDNAR B CLAREMON DA COOK JJ MCINTYRE CJ HUNT CA GOULD RJ LYNCH RJ LYNCH JJ GAUL SL STRANIERI MT SITKO GR HOLAHAN MA GLASS JD HAMILL T GORHAM LM PRUEKSARITANONT T BALDWIN JJ HARTMAN GD
Citation: Bc. Askew et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .17. DESIGN AND SYNTHESISOF ORALLY-ACTIVE, LONG-ACTING NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/, Journal of medicinal chemistry, 40(12), 1997, pp. 1779-1788
NONPEPTIDE GLYCOPROTEIN IIB LIIA INHIBITORS .14. ORAL ANTITHROMBOTIC EFFICACY OF L-738,167 IN A CONSCIOUS CANINE MODEL OF CORONARY-ARTERY ELECTROLYTIC INJURY/
Authors: COOK JJ GLASS JD SITKO GR HOLAHAN MA STUPIENSKI RF WALLACE AA STUMP GL HAND EL ASKEW BC HARTMAN GD GOULD RJ LYNCH JJ
Citation: Jj. Cook et al., NONPEPTIDE GLYCOPROTEIN IIB LIIA INHIBITORS .14. ORAL ANTITHROMBOTIC EFFICACY OF L-738,167 IN A CONSCIOUS CANINE MODEL OF CORONARY-ARTERY ELECTROLYTIC INJURY/, Circulation, 96(3), 1997, pp. 949-958
SPECIES AND ORGAN DIFFERENCES IN FIRST-PASS METABOLISM OF THE ESTER PRODRUG L-751,164 IN DOGS AND MONKEYS - IN-VIVO AND IN-VITRO STUDIES
Authors: PRUEKSARITANONT T GORHAM LM ELLIS JD FERNANDEZMETZLER C DELUNA P GEHRET JR STRONG KL HOCHMAN JH ASKEW BC DUGGAN ME GILBERT JD LIN JH VYAS KP
Citation: T. Prueksaritanont et al., SPECIES AND ORGAN DIFFERENCES IN FIRST-PASS METABOLISM OF THE ESTER PRODRUG L-751,164 IN DOGS AND MONKEYS - IN-VIVO AND IN-VITRO STUDIES, Drug metabolism and disposition, 24(11), 1996, pp. 1263-1271
NOVEL MECHANISM FOR LONG-ACTING GPIIB IIIA ANTAGONISTS/
Authors: BEDNAR RA GAUL SL COOK JJ ASKEW BC HARTMAN GD GOULD RJ BEDNAR B
Citation: Ra. Bednar et al., NOVEL MECHANISM FOR LONG-ACTING GPIIB IIIA ANTAGONISTS/, Circulation, 94(8), 1996, pp. 568-568
NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .6. DESIGN AND SYNTHESIS OF RIGID, CENTRALLY CONSTRAINED NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/
Authors: ASKEW BC MCINTYRE CJ HUNT CA CLAREMON DA GOULD RJ LYNCH RJ ARMSTRONG DJ
Citation: Bc. Askew et al., NONPEPTIDE GLYCOPROTEIN IIB IIIA INHIBITORS .6. DESIGN AND SYNTHESIS OF RIGID, CENTRALLY CONSTRAINED NONPEPTIDE FIBRINOGEN RECEPTOR ANTAGONISTS/, Bioorganic & medicinal chemistry letters, 5(5), 1995, pp. 475-480
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