Authors:
Lopez, H
Vilches, V
Scarano, S
Stepanik, D
Smayevsky, J
Lemme, L
Cardenosa, O
Ambler, J
Sucari, A
Citation: H. Lopez et al., Multicentre study of the in vitro evaluation of moxifloxacin and other quinolones against community acquired respiratory pathogens, INT J ANT A, 18(4), 2001, pp. 379-382
Authors:
Baettig, U
Brown, L
Brundish, D
Dell, C
Furzer, A
Garman, S
Janus, D
Kane, PD
Smith, G
Walker, CV
Cockcroft, XL
Ambler, J
Mitchelson, A
Talbot, MD
Tweed, M
Wills, N
Citation: U. Baettig et al., The design and synthesis of thrombin inhibitors: Analogues of MD805 containing non-polar surrogates for arginine at the P1 position, BIOORG MED, 10(14), 2000, pp. 1563-1566
Authors:
Hayler, J
Kane, PD
LeGrand, D
Lugrin, F
Menear, K
Price, R
Allen, M
Cockcroft, XL
Ambler, J
Butler, K
Dunnet, K
Mitchelson, A
Talbot, M
Tweed, M
Wills, N
Citation: J. Hayler et al., The design and synthesis of thrombin inhibitors: The introduction of in vivo efficacy and oral bioavailability into benzthiazolylalanine inhibitors, BIOORG MED, 10(14), 2000, pp. 1567-1570
Authors:
Ambler, J
Brown, L
Cockcroft, XL
Grutter, M
Hayler, J
Janus, D
Jones, D
Kane, P
Menear, K
Priestle, J
Smith, G
Talbot, M
Walker, CV
Wathey, B
Citation: J. Ambler et al., Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: Ion-dipole interactions with lysine 60G, BIOORG MED, 9(9), 1999, pp. 1317-1322
Authors:
Ambler, J
Bentley, D
Brown, L
Dunnet, K
Farr, D
Janus, D
Le Grand, D
Menear, K
Mercer, M
Talbot, M
Tweed, M
Wathey, B
Citation: J. Ambler et al., The discovery of orally available thrombin inhibitors: Optimisation of theP1 pharmacophore, BIOORG MED, 9(8), 1999, pp. 1103-1108
Authors:
Ambler, J
Baker, E
Bentley, D
Brown, L
Butler, K
Butler, P
Farr, D
Dunnet, K
Le Grand, D
Hayler, J
Janus, D
Jones, D
Menear, K
Mercer, M
Smith, G
Talbot, M
Tweed, M
Citation: J. Ambler et al., Studies towards the identification of potent, selective and bioavailable thrombin inhibitors, BIOORG MED, 9(5), 1999, pp. 737-742
Authors:
Brundish, D
Bull, A
Donovan, V
Fullerton, JD
German, SM
Hayler, JF
Janus, D
Kane, PD
McDonnell, M
Smith, GP
Wakeford, R
Walker, CV
Howarth, G
Hoyle, W
Allen, MC
Ambler, J
Butler, K
Talbot, MD
Citation: D. Brundish et al., Design and synthesis of thrombin inhibitors: Analogues of MD-805 with reduced stereogenicity and improved potency, J MED CHEM, 42(22), 1999, pp. 4584-4603
Authors:
Ambler, J
Baker, E
Brown, L
Butler, P
Farr, D
Dunnet, K
Le Grand, D
Janus, D
Jones, D
Menear, K
Mercer, M
Smith, G
Talbot, M
Tweed, M
Citation: J. Ambler et al., The discovery of orally available thrombin inhibitors: Studies towards theoptimisation of CGH1668, BIOORG MED, 8(24), 1998, pp. 3583-3588